Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sheila J. Raymond"'
Publikováno v:
Neurosurgery. 36:1172-1177
This study investigated the efficacy and safety of delayed therapy with tissue-plasminogen activator (t-PA) in a rabbit model of thromboembolic stroke. The t-PA therapy was started 3, 4, or 5 hours after autologous clot embolization. New Zealand rabb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4488433599dd8b66fcc73dd075740236
https://doi.org/10.1227/00006123-199506000-00017
https://doi.org/10.1227/00006123-199506000-00017
Autor:
Susan P. Fuller, Sheila J. Raymond, Richard H. Dooley, Cordell E. Gross, Martin M. Bednar, Diantha B. Howard
Publikováno v:
Neurological Research. 16:465-470
Transforming growth factor-beta 1 (TGF-beta 1), suggested in some studies to suppress astrocyte and neutrophil function, has also reduced ischaemic brain injury when administered immediately prior to clot embolization in models of thromboembolic stro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ded705f059e413a0c33341e268a761
https://doi.org/10.1080/01616412.1994.11740275
https://doi.org/10.1080/01616412.1994.11740275
Publikováno v:
Neurological Research. 15:405-408
The thrombolytic activity of tissue plasminogen activator was evaluated in a rabbit model of thromboembolic stroke using both various concentrations (3, 5, and 10 mg/kg; 20% bolus with the remaining 80% given over 30 min.) and routes of administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543b7ae8146c26959a22a1a46738c2db
https://doi.org/10.1080/01616412.1993.11740173
https://doi.org/10.1080/01616412.1993.11740173
Publikováno v:
Stroke. 21:1705-1709
Tissue plasminogen activator is an endogenous fibrin-specific serine protease with potent thrombolytic activity. We investigated the efficacy of tissue plasminogen activator in reducing cerebral infarct size after thromboembolic stroke in a rabbit mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bffbc01dad8b36a89fbfbc9a0d488ee
https://doi.org/10.1161/01.str.21.12.1705
https://doi.org/10.1161/01.str.21.12.1705
Autor:
Cordell E. Gross, Sheila J. Raymond-Russell, Harold K. Kimelberg, Martin M. Bednar, Christina Booth
Publikováno v:
Surgical neurology. 47(1)
BACKGROUND Both the 21-aminosteroid U74006F, a potent inhibitor of lipid peroxidation, and L644-711, an anion channel blocker that inhibits both neutrophil and astrocyte function, have been previously shown to reduce brain injury in pretreatment para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a582107e265c01a120ab63e745380a8
https://pubmed.ncbi.nlm.nih.gov/8986168
https://pubmed.ncbi.nlm.nih.gov/8986168
Autor:
Sheila J. Raymond-Russell, Cordell E. Gross, James J. Kohut, Martin M. Bednar, Samuel D. Wright
Publikováno v:
Neurological research. 18(2)
Neutrophil activation and accumulation as a consequence of cerebral ischemia-reperfusion has been suggested to exacerbate tissue injury. The current study is designed to examine the effect of IB4, a monoclonal antibody directed against the neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6c1228b57eefb609dd9e2b07abe0ae
https://pubmed.ncbi.nlm.nih.gov/9162874
https://pubmed.ncbi.nlm.nih.gov/9162874
Publikováno v:
Neurological research. 18(1)
The successful application of thrombolytic therapy to acute myocardial infarction has prompted a reinvestigation of thrombolytic therapy for acute stroke. However, an examination of safety and efficacy of thrombolytic therapy in acute thromboembolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64453c813c44c9a6bd0ac73c31e8bc2
https://pubmed.ncbi.nlm.nih.gov/8714536
https://pubmed.ncbi.nlm.nih.gov/8714536
Autor:
Martin M. Bednar, Julie C. Fanburg, Michael L. Anderson, Sheila J. Raymond, Cordell E. Gross, Richard H. Dooley
Publikováno v:
Neurological research. 16(2)
The present study was performed to compare brain infarct size assessment by routine histology (haematoxylin and eosin) and by 2,3,5-triphenyltetrazolium chloride staining techniques. New Zealand white rabbits were subjected to autologous clot emboliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61c8c0acff362b10f86720914e318ce
https://pubmed.ncbi.nlm.nih.gov/7519330
https://pubmed.ncbi.nlm.nih.gov/7519330
Publikováno v:
Neurosurgery. 31(5)
U74006F, a novel 21-aminosteroid, is an inhibitor of iron-dependent lipid peroxidation that is devoid of glucocorticoid and mineralocorticoid side effects. The efficacy of U74006F in reducing cerebral infarct size was investigated in a rabbit model o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e2bb8400f78a7a51e201e4092ee084
https://pubmed.ncbi.nlm.nih.gov/1436419
https://pubmed.ncbi.nlm.nih.gov/1436419
Publikováno v:
The Journal of trauma. 32(6)
The direct effect of tumor necrosis factor (TNF), a product of activated macrophages, on myocardial performance was determined using an isolated papillary muscle technique and a modified Langendorff preparation. Papillary muscle was obtained from mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2682697a1f2d9a8d2575fdd88a79b764
https://pubmed.ncbi.nlm.nih.gov/1613827
https://pubmed.ncbi.nlm.nih.gov/1613827