Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sheila J. MacLean"'
Publikováno v:
Mechanisms of Development. 116(1-2):193-197
Potassium channels vary in their function and regulation, yet they maintain a number of important features - they are involved in the control of potassium flow, cell volume, cell membrane resting potential, cell excitability and hormone release. The
The tissue polarity gene nemo carries out multiple roles in patterning during Drosophila development
Autor:
Esther M. Verheyen, Sheila J. MacLean, Bryan C. Andrews, Ivana Mirkovic, Christina MacKinnon, Caillin Langmann
Publikováno v:
Mechanisms of Development. 101(1-2):119-132
Drosophila nemo was first identified as a gene required for tissue polarity during ommatidial development. We have extended the analysis of nemo and found that it participates in multiple developmental processes. It is required during wing developmen
Autor:
Sheila J. Maclean, David M. Gibson
Publikováno v:
Immunogenetics. 45:223-225
Autor:
David M. Gibson, Abdellah Souleimani, William A. Home, Dhani Nallainathan, Diane Cloutier, Nicolas Pilon, Pascal Bouffard, Christine Gagnon, Sheila J. MacLean
Publikováno v:
Journal of immunological methods. 187(1)
We describe a new approach to analysis of T cell receptor diversity based on isoelectric focusing of in vitro translation products of amplified V region genes. The method is illustrated by analysis of V beta 2 profiles in peripheral blood lymphocytes
Publikováno v:
Immunogenetics. 18:111-116
Recombination has been detected for the first time between chromosome 6 loci controlling kappa chain expression in normal mouse serum immunoglobulin and the Lyt-3 locus. The recombination event occurred at the 26th or 27th backcross generation during
Publikováno v:
Immunogenetics. 20:493-501
In this study we report the first instance of recombination between kappa chain genetic markers in the mouse. The recombination frequency, 0.45% (95% limits, 0.12–1.61), is similar to that previously found for recombination between the kappa chain
Publikováno v:
Journal of immunological methods. 79(2)
A technique is described for the characterization of immunoglobulin light chains of hybridomas in culture. Immunoglobulins biosynthetically labelled with 14C are obtained from culture supernatants. Following complete reduction and alkylation light ch