Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sheila H. Jacobo"'
Autor:
Sheila H. Jacobo, Scott R. Tweedie, Alexander S. Filatov, Sergiy G. Krasutsky, Ravi Krishnamoorthy
Publikováno v:
Organic Process Research & Development. 19:284-289
Early process development toward the scalable production of taxadienone on a decagram scale is described. A continuous flow reactor was employed to safely run a potentially hazardous cyclopropane ring opening. The route featured two copper-mediated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a47987c40c2db521b206d3989c950ef1
https://doi.org/10.1021/op500314c
https://doi.org/10.1021/op500314c
Autor:
Chih-Tsung Chang, John A. Lawson, Domenico Pratico, Joshua Rokach, Sheila H. Jacobo, Gue-Jae Lee, Garret A. FitzGerald, William S. Powell
Publikováno v:
The Journal of Organic Chemistry. 71:1370-1379
[reaction: see text] A new and stereoselective approach for the synthesis of all-syn isoprostanes is reported. This method, which is based on acid-catalyzed Diels-Alder reaction, allows the introduction of the side chain with a predetermined stereoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809ce5259d2c23ab049195485073245a
https://doi.org/10.1021/jo051916x
https://doi.org/10.1021/jo051916x
Autor:
William S. Powell, Joshua Rokach, Sheila H. Jacobo, Garret A. FitzGerald, Domenico Praticò, John A. Lawson, Chih-Tsung Chang
Publikováno v:
Tetrahedron Letters. 46:6325-6328
A new and efficient approach to 4(S)-hydroxycyclopent-2-enone is presented. This methodology allows the preparation of 4(S)-hydroxycyclopent-2-enone in large scale and with high optical purity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc78dbda25432d8a0f07242a003a81c
https://doi.org/10.1016/j.tetlet.2005.07.035
https://doi.org/10.1016/j.tetlet.2005.07.035
Autor:
Sergiy G. Krasutsky, Sheila H. Jacobo
Publikováno v:
International Journal of Chemistry. 8:64
The chiral copper-catalyzed conjugate addition is a well-developed methodology to create asymmetric C-C bonds. Many efforts have been dedicated to design efficient systems and identifying highly efficient ligands. Among the most proficient ligands, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfafb735d05c3980e8cd79b711632574
https://doi.org/10.5539/ijc.v8n2p64
https://doi.org/10.5539/ijc.v8n2p64
Autor:
Ravi Krishnamoorthy, S R Tweedie, Sheila H. Jacobo, Alexander S. Filatov, Sergiy G. Krasutsky
Publikováno v:
Synfacts. 11:0355-0355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::990c51333708dfc3b06ffe00681f6279
https://doi.org/10.1055/s-0034-1380334
https://doi.org/10.1055/s-0034-1380334
Autor:
William S. Powell, Joshua Rokach, Mustafa Adiyaman, Sheila H. Jacobo, Chih-Tsung Chang, Namin Kang
Publikováno v:
ChemInform. 36
The cyanide-ring opening of thionocarbonates with NaCN in DMF and TBACN in THF is described. This reaction occurred regioselectively to afford β-hydroxy nitrile with preserved stereochemistry of the hydroxy group in high yield.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a6b4f4e4b5273f39bfe22370480f9a9
https://doi.org/10.1002/chin.200514054
https://doi.org/10.1002/chin.200514054
Autor:
Joshua Rokach, Seongjin Kim, Domenico Praticò, Sheila H. Jacobo, John A. Lawson, William S. Powell, Garret A. FitzGerald, Kirk M. Maxey
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(6)
The first total synthesis of 17,18,19,20-d4-iPF2alpha-III 32, a deuterated analog of iPF2alpha-III, is described. We have used this analog in some beta-oxidation studies with rat liver homogenates and have shown that 32 was metabolized to 17,18,19,20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c555c74008bdaed0e1e0a30ee39d17
https://pubmed.ncbi.nlm.nih.gov/15745808
https://pubmed.ncbi.nlm.nih.gov/15745808