Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sheila C Nardelli"'
Autor:
Danielle Gomes Passos Silva, Selma da Silva Santos, Sheila C Nardelli, Isabela Cecília Mendes, Anna Cláudia Guimarães Freire, Bruno Marçal Repolês, Bruno Carvalho Resende, Héllida Marina Costa-Silva, Verônica Santana da Silva, Karla Andrade de Oliveira, Camila Franco Batista Oliveira, Liza Figueiredo Felicori Vilela, Ronaldo Alves Pinto Nagem, Glória Regina Franco, Andrea Mara Macedo, Sergio Danilo Junho Pena, Erich Birelli Tahara, Policarpo Ademar Sales Junior, Douglas Souza Moreira, Santuza Maria Ribeiro Teixeira, Richard McCulloch, Stela Virgilio, Luiz Ricardo Orsini Tosi, Sergio Schenkman, Luciana Oliveira Andrade, Silvane Maria Fonseca Murta, Carlos Renato Machado
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 11, p e0006875 (2018)
In Trypanosoma cruzi, the etiologic agent of Chagas disease, Rad51 (TcRad51) is a central enzyme for homologous recombination. Here we describe the different roles of TcRad51 in DNA repair. Epimastigotes of T. cruzi overexpressing TcRAD51 presented a
Externí odkaz:
https://doaj.org/article/36c29e39f2654429899460add329f872
Autor:
Sheila C. Nardelli, Natalie C. Silmon de Monerri, Laura Vanagas, Xiaonan Wang, Zoi Tampaki, William J. Sullivan, Sergio O. Angel, Kami Kim
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Toxoplasma gondii is a protozoan parasite that differentiates from acute tachyzoite stages to latent bradyzoite forms in response to environmental cues that modify the epigenome. We studied the distribution of the histone variants
Externí odkaz:
https://doaj.org/article/10c23c4f11354703bec2f0af5de0c31f
The Histone Code of Toxoplasma gondii Comprises Conserved and Unique Posttranslational Modifications
Autor:
Sheila C. Nardelli, Fa-Yun Che, Natalie C. Silmon de Monerri, Hui Xiao, Edward Nieves, Carlos Madrid-Aliste, Sergio O. Angel, William J. Sullivan, Ruth H. Angeletti, Kami Kim, Louis M. Weiss
Publikováno v:
mBio, Vol 4, Iss 6 (2013)
ABSTRACT Epigenetic gene regulation has emerged as a major mechanism for gene regulation in all eukaryotes. Histones are small, basic proteins that constitute the major protein component of chromatin, and posttranslational modifications (PTM) of hist
Externí odkaz:
https://doaj.org/article/1e343f8eba504215b807448f124868f7
Autor:
Fa-Yun Che, Ruth Hogue Angeletti, Kami Kim, Peng Wu, Natalie C. Silmon de Monerri, Myrasol Calloway, Sheila C. Nardelli, Louis M. Weiss, Edward Nieves
Publikováno v:
The FASEB Journal. 27
Publikováno v:
Trends in parasitology. 28(5)
Chromatin structure plays a vital role in epigenetic regulation of protozoan parasite gene expression. Epigenetic gene regulation impacts parasite virulence, differentiation and cell cycle control. Recent work in many laboratories has elucidated the
Publikováno v:
Advances in parasitology. 75
The presence of nucleus in living organisms characterizes the Eukaryote domain. The nucleus compartmentalizes the genetic material surrounded by a double membrane called nuclear envelope. The nucleus has been observed since the advent of the light mi