Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sheila C Boddy"'
Autor:
Rob D Catalano, Martin R Wilson, Sheila C Boddy, Andrew T M McKinlay, Kurt J Sales, Henry N Jabbour
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19209 (2011)
The prostaglandin endoperoxide synthase (PTGS) pathway is a potent driver of tumour development in humans by enhancing the biosynthesis and signalling of prostaglandin (PG) E(2). PTGS2 expression and PGE(2) biosynthesis is elevated in endometrial ade
Externí odkaz:
https://doaj.org/article/b305baf862fa490296e8bb2818870dc0
Publikováno v:
REPRODUCTION. 142:345-352
Lipoxin A4is a lipid mediator that elicits anti-inflammatory and pro-resolution actions via its receptor, formyl peptide receptor 2 (FPR2/ALX). In this study, we aimed to investigate the expression and potential role of lipoxin A4and FPR2/ALX in the
Publikováno v:
Molecular Human Reproduction
Prostanoids are well-described primary mediators of inflammatory processes and are essential for the normal physiological function of the female reproductive system. The aim of this study was to determine the temporal expression of the prostanoid bio
Publikováno v:
Oncogene. 27:2466-2477
Cellular adhesion to extracellular matrix is a central phenomenon for the maintenance of tissue integrity and cellular movement. Collectively, these processes are regulated by a fine-tuned balance between the formation and loosening of adhesive conta
Autor:
Henry N. Jabbour, Sheila C. Boddy
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:4481-4487
In this study, we investigated the effect of prostaglandin E(2) (PGE(2)) on MAPK ERK1/2 protein phosphorylation and on proliferation of epithelial cells of the human endometrium. Treatment of proliferative phase endometrium with PGE(2) induced rapid
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:4453-4459
This study was designed to elucidate the sites of synthesis and action of PGE(2) in the nonpregnant human uterus across the menstrual cycle. The sites of expression of PGE synthase and synthesis of PGE(2) were investigated by immunohistochemistry usi
Publikováno v:
Reproduction (Cambridge, England)
Lipoxin A(4) is a lipid mediator that elicits anti-inflammatory and pro-resolution actions via its receptor, formyl peptide receptor 2 (FPR2/ALX). In this study, we aimed to investigate the expression and potential role of lipoxin A(4) and FPR2/ALX i
Autor:
Alistair R.W. Williams, Kurt J. Sales, Henry N. Jabbour, Sheila C. Boddy, Richard A. Anderson
Publikováno v:
Endocrinology. 148(8)
Prostaglandin (PG) F(2alpha) is a potent bioactive lipid in the female reproductive tract, and exerts its function after coupling with its heptahelical G-protein-coupled receptor [F-series-prostanoid (FP) receptor] to initiate cell signaling and targ
Publikováno v:
Molecular and cellular endocrinology. 252(1-2)
Prostaglandins are bioactive lipids produced from arachidonic acid by cyclooxygenase enzymes and specific terminal prostanoid synthase enzymes. Following biosynthesis, prostaglandins exert an autocrine/paracrine function by coupling to specific prost
Autor:
Kurt J. Sales, Richard A. Anderson, Henry N. Jabbour, Alistair R.W. Williams, Zvi Naor, Tammy List, Sheila C. Boddy
Publikováno v:
Sales, K J, List, T, Boddy, S C, Williams, A R W, Anderson, R A, Naor, Z & Jabbour, H N 2005, ' A novel angiogenic role for prostaglandin F2alpha-FP receptor interaction in human endometrial adenocarcinomas ', Cancer Research, vol. 65, no. 17, pp. 7707-16 . https://doi.org/10.1158/0008-5472.CAN-05-0101
Prostaglandins have been implicated in several neovascular diseases. In the present study, we found elevated FP receptor and vascular endothelial growth factor (VEGF) expression colocalized in glandular epithelial and vascular cells lining the blood