Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sheila Abril"'
Autor:
Ángel Cores, Sheila Abril, Patrycja Michalska, Pablo Duarte, Ana I. Olives, M. Antonia Martín, Mercedes Villacampa, Rafael León, J. Carlos Menéndez
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 941 (2021)
Oxidative stress is crucial to the outbreak and advancement of neurodegenerative diseases and is a common factor to many of them. We describe the synthesis of a library of derivatives of the 4-arylmethylen-2-pyrrolin-5-one framework by sequential app
Externí odkaz:
https://doaj.org/article/6be1abc283a2479e926a53edd8e48637
Autor:
Ana I. Olives, Mercedes Villacampa, Rafael León, Pablo Daniel Palacios Duarte, Patrycja Michalska, Ángel Cores, M. Antonia Martín, Sheila Abril, J. Carlos Menéndez
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
instname
Digital.CSIC. Repositorio Institucional del CSIC
Antioxidants
Volume 10
Issue 6
Biblos-e Archivo. Repositorio Institucional de la UAM
Universitat Autònoma de Barcelona
Antioxidants, Vol 10, Iss 941, p 941 (2021)
instname
Digital.CSIC. Repositorio Institucional del CSIC
Antioxidants
Volume 10
Issue 6
Biblos-e Archivo. Repositorio Institucional de la UAM
Universitat Autònoma de Barcelona
Antioxidants, Vol 10, Iss 941, p 941 (2021)
Oxidative stress is crucial to the outbreak and advancement of neurodegenerative diseases and is a common factor to many of them. We describe the synthesis of a library of derivatives of the 4-arylmethylen-2-pyrrolin-5-one framework by sequential app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966cf1b3f2c0bd87f4145f677f7c21a3
https://eprints.ucm.es/id/eprint/71862/1/antioxidants-10-00941-v3.pdf
https://eprints.ucm.es/id/eprint/71862/1/antioxidants-10-00941-v3.pdf
Publikováno v:
Carbohydrate Polymers. 157:94-104
ITH12674 is a multitarget drug, designed to exert a dual "drug-prodrug" mechanism of action, able to induce the phase II antioxidant and anti-inflammatory response for the treatment of brain ischemia. However, its physicochemical properties limit its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d538ee4cb5400683002f7d6f6f44be
https://doi.org/10.1016/j.carbpol.2016.09.072
https://doi.org/10.1016/j.carbpol.2016.09.072
Autor:
Elisa Navarro, Javier Egea, Isabel Gameiro, Laura González-Lafuente, Rafael León, Manuela G. López, Izaskun Buendia, Sheila Abril, Alicia Gómez López, Patrycja Michalska
Publikováno v:
Future medicinal chemistry. 7(15)
Background: Neurodegenerative diseases share many pathological pathways, such as abnormal protein aggregation, mitochondrial dysfunction, extensive oxidative stress and neuroinflammation. Cells have an intrinsic mechanism of protection, the Nrf2 tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed69774c7f0f222f8d861a7fcd8678f6
https://pubmed.ncbi.nlm.nih.gov/26496465
https://pubmed.ncbi.nlm.nih.gov/26496465