Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Sheila A. Stewart"'
Autor:
Benjamin Assouline, Rachel Kahn, Lutfi Hodali, Reba Condiotti, Yarden Engel, Ela Elyada, Tzlil Mordechai-Heyn, Jason R. Pitarresi, Dikla Atias, Eliana Steinberg, Tirza Bidany-Mizrahi, Esther Forkosh, Lior H. Katz, Ofra Benny, Talia Golan, Matan Hofree, Sheila A. Stewart, Karine A. Atlan, Gideon Zamir, Ben Z. Stanger, Michael Berger, Ittai Ben-Porath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Senescent cells within tumors and their stroma exert complex pro- and anti-tumorigenic functions. However, the identities and traits of these cells, and the potential for improving cancer therapy through their targeting, remain poorly charac
Externí odkaz:
https://doaj.org/article/3aed130938ea4e87851508070eec5837
Autor:
Qihao Ren, Sheila A. Stewart
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100585- (2024)
Externí odkaz:
https://doaj.org/article/6e6f17aa3e8f49b48aa503ef64185365
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100591- (2024)
Externí odkaz:
https://doaj.org/article/a46bc24c16504879b66aa251cd0e5472
Autor:
Ganesh Kumar Raut, Zhangting Yao, Xianmin Luo, Qihao Ren, Taylor Malachowski, Douglas V. Faget, Sheila A. Stewart
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100531- (2024)
Externí odkaz:
https://doaj.org/article/f495f247e1ae4dc3b7d0e2284b87a5cb
Autor:
Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100534- (2024)
Externí odkaz:
https://doaj.org/article/68141490621946f3a9066df6df8be2eb
Autor:
Lauren Broestl, Nicole M. Warrington, Lucia Grandison, Tamara Abou-Antoun, Olivia Tung, Saraswati Shenoy, Miranda M. Tallman, Gina Rhee, Wei Yang, Jasmin Sponagel, Lihua Yang, Najla Kfoury-Beaumont, Cameron M. Hill, Sulaiman A. Qanni, Diane D. Mao, Albert H. Kim, Sheila A. Stewart, Monica Venere, Jingqin Luo, Joshua B. Rubin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
In human and murine GBM cells, and wildtype murine astrocytes, radiation induces senescence. Overall, female cells are more sensitive to radiation and to p21-induced senescence. This may contribute to the female survival advantage in GBM.
Externí odkaz:
https://doaj.org/article/4742c6c411eb4925a75c4718df397b65
Autor:
Qihao Ren, Weng Hua Khoo, Alexander P. Corr, Tri Giang Phan, Peter I. Croucher, Sheila A. Stewart
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-16 (2022)
Abstract Background Breast cancer can recur months to decades after an initial diagnosis and treatment. The mechanisms that control tumor cell dormancy remain poorly understood, making it difficult to predict which patients will recur and thus benefi
Externí odkaz:
https://doaj.org/article/22152aae55594e4188f347c69ed564c0
Autor:
Megan K. Ruhland, Andrew J. Loza, Aude-Helene Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, Kathleen Leahy, Jingqin Luo, Andras Schaffer, John R. Edwards, Gregory Longmore, Roberta Faccio, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
The risk of developing cancer increases with age. Here, the authors address the contribution of age-dependent accumulation of senescent cells within the tumour stroma compartment and show that senescent cells increase the infiltration of myeloid-deri
Externí odkaz:
https://doaj.org/article/fa867a0d00a840c499859677d3888265
Autor:
Xianmin Luo, Yujie Fu, Andrew J. Loza, Bhavna Murali, Kathleen M. Leahy, Megan K. Ruhland, Margery Gang, Xinming Su, Ali Zamani, Yu Shi, Kory J. Lavine, David M. Ornitz, Katherine N. Weilbaecher, Fanxin Long, Deborah V. Novack, Roberta Faccio, Gregory D. Longmore, Sheila A. Stewart
Publikováno v:
Cell Reports, Vol 14, Iss 1, Pp 82-92 (2016)
More than 85% of advanced breast cancer patients suffer from metastatic bone lesions, yet the mechanisms that facilitate these metastases remain poorly understood. Recent studies suggest that tumor-derived factors initiate changes within the tumor mi
Externí odkaz:
https://doaj.org/article/d637abeba09f4ec789b2549d8c87f54d
Autor:
Douglas V. Faget, Xianmin Luo, Matthew J. Inkman, Qihao Ren, Xinming Su, Kai Ding, Michael R. Waters, Ganesh Kumar Raut, Gaurav Pandey, Paarth B. Dodhiawala, Renata Ramalho-Oliveira, Jiayu Ye, Thomas Cole, Bhavna Murali, Alexander Zheleznyak, Monica Shokeen, Kurt R. Weiss, Joseph B. Monahan, Carl J. DeSelm, Adrian V. Lee, Steffi Oesterreich, Katherine N. Weilbaecher, Jin Zhang, David G. DeNardo, Sheila A. Stewart
Publikováno v:
Cancer Discovery. :OF1-OF24
Metastatic breast cancer is an intractable disease that responds poorly to immunotherapy. We show that p38MAPKα inhibition (p38i) limits tumor growth by reprogramming the metastatic tumor microenvironment in a CD4+ T cell-, IFNγ-, and macrophage-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c99f40122f5e1ab8ee6b87545b7dea6
https://doi.org/10.1158/2159-8290.cd-22-0907
https://doi.org/10.1158/2159-8290.cd-22-0907