Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sheila A. Hunter"'
Autor:
Sumner Burstein, Sheila A. Hunter, Ronald G. Rossetti, John M. Goldberg, Robert B. Zurier, Joan H. Lane
Publikováno v:
Arthritis & Rheumatism. 41:163-170
Objective To assess the antiinflammatory activity of dimethylheptyl-THC-11 oic acid (DMH-11C), a nonpsychoactive synthetic derivative of tetrahydrocannabinol. Methods Acute inflammation was induced by injection of interleukin-1β and tumor necrosis f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c502e2f59893b4414969e8311a77a9a
https://doi.org/10.1002/1529-0131(199801)41:1<163::aid-art20>3.0.co
https://doi.org/10.1002/1529-0131(199801)41:1<163::aid-art20>3.0.co
Autor:
Sheila A. Hunter, Sumner Burstein
Publikováno v:
Life Sciences. 60:1563-1573
Numerous reports have suggested that increased synthesis of eicosanoids is a significant effect of cannabinoids in several models including the human. To address the question of receptor mediation in this process we have carried out experiments using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0c14f911c3e91c6a659e71e5e71e73
https://doi.org/10.1016/s0024-3205(97)00122-7
https://doi.org/10.1016/s0024-3205(97)00122-7
Autor:
Sumner Burstein, Sheila A. Hunter
Publikováno v:
Biochemical Pharmacology. 49:855-858
A concentration-related stimulation of anandamide (arachidonylethanolamide) synthesis by delta 9-tetrahydrocannabinol (THC) was observed in N-18TG2 neuroblastoma cells. Anandamide was detected and measured using an approach in which [3H]arachidonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2258fa5d1a85050a0e71ed65bba3bc6a
https://doi.org/10.1016/0006-2952(94)00538-w
https://doi.org/10.1016/0006-2952(94)00538-w
Publikováno v:
Pharmacology Biochemistry and Behavior. 40:559-563
The release of arachidonic acid from mouse peritoneal and S49 cells induced by delta 1-tetrahydrocannabinol was found to be altered by prior exposure of the cells to either pertussis toxin or cholera toxin. The stable analogs of GTP and GDP, GTP-gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989ccd95bae841dc4d9a9077608f2deb
https://doi.org/10.1016/0091-3057(91)90363-7
https://doi.org/10.1016/0091-3057(91)90363-7
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 43:185-190
An isotopic dilution procedure using specific prostaglandin E2 (PGE2) brain receptors was utilized to determine the changes in brain PGE2 levels subsequent to drug exposure. Delta-1-tetrahydrocannabinol (delta 1-THC) stimulated PGE2 synthesis resulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3a2acc12430fdbde89da8f8c116239
https://doi.org/10.1016/0952-3278(91)90167-4
https://doi.org/10.1016/0952-3278(91)90167-4
Autor:
Sumner Burstein, Alexandros Makriyannis, Yan Guo, Sharon A. Doyle, Charlene A. Audette, Sheila A. Hunter, Avgui Charalambous
Publikováno v:
Biochemical and Biophysical Research Communications. 176:492-497
A novel [ 125 I]-labelled photoaffinity ligand designed to detect cannabinoid binding sites has been used in mouse brain preparations and in cultured S49 mouse lymphoma cells. The ligand, 2-iodo-5′-azido-Δ 8 -THC, shows a high affinity for sites i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200b98303b4de123ebd9f980ef11999c
https://doi.org/10.1016/0006-291x(91)90951-3
https://doi.org/10.1016/0006-291x(91)90951-3
Publikováno v:
Journal of the American Academy of Nurse Practitioners. 11(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087b57bfb79cafe70ddc60214c124a0c
https://pubmed.ncbi.nlm.nih.gov/10504922
https://pubmed.ncbi.nlm.nih.gov/10504922
Autor:
Joan H. Lane, Robert B. Zurier, Sumner Burstein, Ronald G. Rossetti, Sheila A. Hunter, John M. Goldberg
Publikováno v:
Marihuana and Medicine ISBN: 9781475757170
THC-11-oic acid, a non-psychoactive derivative of Δ9-THC, inhibits cyclooxygenase and platelet-activating factors, which are the mechanisms of prostaglandin inhibition by the nonsteroid antiinflammatory drugs (NSAID’s). A dimethylheptyl THC (DMH-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de1fde922b4b81ca645ebbb913a4c12
https://doi.org/10.1007/978-1-59259-710-9_49
https://doi.org/10.1007/978-1-59259-710-9_49
Publikováno v:
Journal of Pharmacy Technology. 9:144-145
Objective To determine whether synthetic human calcitonin is a safe and effective treatment for hypercalcemia of malignancy. Data Sources Journal articles published between 1978 and 1992; manufacturers’ package inserts. Study Selection Articles con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f44c3953fac7ee1f1f1b9f2679e102
https://doi.org/10.1177/875512259300900403
https://doi.org/10.1177/875512259300900403
Publikováno v:
Life Sciences. 23:979-982
Δ 1 -Tetrahydrocannabinol was found to inhibit the action of esterases derived from rat adrenal and luteinized ovary on exogenous cholesteryl palmitate. The drug was effective at a dose of 3.2μM causing greater than 30% inhibition; at 16μM almost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebf8c2b1777c1934968330ae77209a5
https://doi.org/10.1016/0024-3205(78)90225-4
https://doi.org/10.1016/0024-3205(78)90225-4