Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sheila A. Brown"'
Autor:
Alice H. Costain, Alexander T. Phythian-Adams, Stefano A. P. Colombo, Angela K. Marley, Christian Owusu, Peter C. Cook, Sheila L. Brown, Lauren M. Webb, Rachel J. Lundie, Jessica G. Borger, Hermelijn H. Smits, Matthew Berriman, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/f40c387517a24427bc98e66dd0734278
Autor:
Alice H. Costain, Alexander T. Phythian-Adams, Stefano A. P. Colombo, Angela K. Marley, Christian Owusu, Peter C. Cook, Sheila L. Brown, Lauren M. Webb, Rachel J. Lundie, Jessica G. Borger, Hermelijn H. Smits, Matthew Berriman, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Schistosomiasis is a disease of global significance, with severity and pathology directly related to how the host responds to infection. The immunological narrative of schistosomiasis has been constructed through decades of study, with researchers of
Externí odkaz:
https://doaj.org/article/a17dd1fb55d94caead4e94f6c0c5976b
Autor:
Allison J. Bancroft, Colin W. Levy, Thomas A. Jowitt, Kelly S. Hayes, Seona Thompson, Edward A. Mckenzie, Matthew D. Ball, Eamon Dubaissi, Aidan P. France, Bruno Bellina, Catherine Sharpe, Aleksandr Mironov, Sheila L. Brown, Peter C. Cook, Andrew S. MacDonald, David J. Thornton, Richard K. Grencis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In the study, the authors identify a protein excreted by the parasite Trichuris muris, p43, which can modulate IL-13 function, a key cytokine involved in host protection. These data suggest that p43 may be a novel therapeutic target for both whipworm
Externí odkaz:
https://doaj.org/article/e790a9921fd644c2949b6cd1e5687605
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The balance of type 1 and type 2 immune responses plays a crucial role in anti-helminth immunity and can either support chronic infection or drive type 2 mediated expulsion of the parasite. Helminth antigens and secreted molecules directly influence
Externí odkaz:
https://doaj.org/article/e7bbfc56d7a743d2892fbf561c37b368
Autor:
Gareth-Rhys Jones, Sheila L. Brown, Alexander T. Phythian-Adams, Alasdair C. Ivens, Peter C. Cook, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Methyl-CpG-binding domain-2 (Mbd2) acts as an epigenetic regulator of gene expression, by linking DNA methylation to repressive chromatin structure. Although Mbd2 is widely expressed in gastrointestinal immune cells and is implicated in regulating in
Externí odkaz:
https://doaj.org/article/dd2f5d7c60144ddaa8f748e5cffa09c8
Autor:
Gareth-Rhys Jones, Calum C. Bain, Thomas M. Fenton, Aoife Kelly, Sheila L. Brown, Alasdair C. Ivens, Mark A. Travis, Peter C. Cook, Andrew S. MacDonald
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Macrophages are pivotal in coordinating a range of important processes in the intestines, including controlling intracellular infections and limiting damaging inflammation against the microbiota. However, it is not clear how gut macrophag
Externí odkaz:
https://doaj.org/article/02f91075a9fe408db349d06087d0454c
Autor:
Heather Hulme, Lynsey M. Meikle, Nicole Strittmatter, John Swales, Gregory Hamm, Sheila L. Brown, Simon Milling, Andrew S. MacDonald, Richard J.A. Goodwin, Richard Burchmore, Daniel M. Wall
Publikováno v:
Hulme, H, Meikle, L M, Strittmatter, N, Swales, J, Hamm, G, Brown, S L, Milling, S, MacDonald, A S, Goodwin, R J A, Burchmore, R & Wall, D M 2022, ' Mapping the Influence of the Gut Microbiota on Small Molecules across the Microbiome Gut Brain Axis ', Journal of the American Society for Mass Spectrometry, vol. 33, no. 4, pp. 649-659 . https://doi.org/10.1021/jasms.1c00298
Microbes exert influence across the microbiome-gut-brain axis through neurotransmitter production, induction of host immunomodulators, or the release or induction of other microbial or host molecules. Here, we used mass spectrometry imaging (MSI), a
Publikováno v:
Journal of Perinatal & Neonatal Nursing. 34:346-351
Late preterm (LPT) infants are at an increased risk for hyperbilirubinemia. Accurate identification and early treatment are needed for optimal health outcomes. In a newborn nursery at an academic medical center, bilirubin levels were drawn at 24 hour
Background The evidence base relating to women's engagement and experiences of postnatal care following Gestational Diabetes Mellitus in the United Kingdom is limited. Additionally, the uptake of a postnatal fasting blood glucose testing following Ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594013bda71968d3b8c0f50a77eb213f
https://orca.cardiff.ac.uk/id/eprint/152255/1/1-s2.0-S0266613821001224-main.pdf
https://orca.cardiff.ac.uk/id/eprint/152255/1/1-s2.0-S0266613821001224-main.pdf
Autor:
Gareth-Rhys, Jones, Sheila L, Brown, Alexander T, Phythian-Adams, Alasdair C, Ivens, Peter C, Cook, Andrew S, MacDonald
Publikováno v:
Frontiers in Immunology
Methyl-CpG-binding domain-2 (Mbd2) acts as an epigenetic regulator of gene expression, by linking DNA methylation to repressive chromatin structure. Although Mbd2 is widely expressed in gastrointestinal immune cells and is implicated in regulating in