Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Sheila A, Baker"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The voltage-gated calcium channel, Cav1.4 is localized to photoreceptor ribbon synapses and functions both in molecular organization of the synapse and in regulating release of synaptic vesicles. Mutations in Cav1.4 subunits typically present as eith
Externí odkaz:
https://doaj.org/article/9732e646ac224baab601a6e84ffe7af6
Autor:
Brittni A Scruggs, Sajag Bhattarai, Megan Helms, Ioana Cherascu, Adisa Salesevic, Elliot Stalter, Joseph Laird, Sheila A Baker, Arlene V Drack
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0276298 (2022)
ObjectiveTo evaluate efficacy of a novel adeno-associated virus (AAV) vector, AAV2/4-RS1, for retinal rescue in the retinoschisin knockout (Rs1-KO) mouse model of X-linked retinoschisis (XLRS). Brinzolamide (Azopt®), a carbonic anhydrase inhibitor,
Externí odkaz:
https://doaj.org/article/047284ca7ac9401b960ee6f7dea8919d
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0268335 (2022)
Hyperpolarization activated cyclic nucleotide-gated channel 1 (HCN1) is expressed throughout the nervous system and is critical for regulating neuronal excitability, with mutations being associated with multiple forms of epilepsy. Adaptive modulation
Externí odkaz:
https://doaj.org/article/b51eaac1369c4b3c86254f7d10bb069d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Vision, hearing, smell, taste, and touch are the tools used to perceive and navigate the world. They enable us to obtain essential resources such as food and highly desired resources such as mates. Thanks to the investments in biomedical research the
Externí odkaz:
https://doaj.org/article/b2f5313304f548ba8b7f0835df6f765b
Autor:
J Wesley Maddox, Kate L Randall, Ravi P Yadav, Brittany Williams, Jussara Hagen, Paul J Derr, Vasily Kerov, Luca Della Santina, Sheila A Baker, Nikolai Artemyev, Mrinalini Hoon, Amy Lee
Publikováno v:
eLife, Vol 9 (2020)
Synapses are fundamental information processing units that rely on voltage-gated Ca2+ (Cav) channels to trigger Ca2+-dependent neurotransmitter release. Cav channels also play Ca2+-independent roles in other biological contexts, but whether they do s
Externí odkaz:
https://doaj.org/article/d845a9afcfb4465486acb38aa3e57c36
Publikováno v:
Acta Crystallographica Section D Structural Biology. 78:792-802
The Kv family of voltage-gated potassium channels regulate neuronal excitability. The biophysical characteristic of Kv channels can be matched to the needs of different neurons by forming homotetrameric or heterotetrameric channels within one of four
Autor:
Yumiko Umino, Sheila A. Baker, Deepak Poria, Colten K Lankford, Eduardo Solessio, Vladimir J. Kefalov
Publikováno v:
J Neurosci
Signal integration of converging neural circuits is poorly understood. One example is in the retina where the integration of rod and cone signaling is responsible for the large dynamic range of vision. The relative contribution of rods versus cones i
Publikováno v:
Journal of Materials Chemistry C. 10:8824-8833
Ubiquitous carbon dot synthesis by-products generate photocurrent, impacting overall device performance, highlighting the urgency of enhanced scrutiny and more rigorous purification protocols and, in many cases, reevaluation of previous results.
Autor:
Shivangi M. Inamdar, Deepak Poria, Colten K Lankford, Joseph G. Laird, Vladimir J. Kefalov, Sheila A. Baker, Eduardo Solessio
Publikováno v:
Hum Mol Genet
The voltage-gated potassium channel responsible for controlling photoreceptor signaling is a heteromeric complex of Kv2.1 subunits with a regulatory Kv8.2 subunit. Kv2.1/Kv8.2 channels are localized to the photoreceptor inner segment and carry IKx, l
Publikováno v:
Journal of Advanced Academics. 32:92-131
This article describes three female professors’ experiences to attain degrees (bachelor’s, master’s, and doctorate) as first-generation college students (FGCS) and become academics. Their individual stories are shared through narratives, which