Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Sheikh Azimullah"'
Publikováno v:
Heliyon, Vol 8, Iss 11, Pp e11434- (2022)
Citronellol, a monoterpene found in the essential oils of Cymbopogo plants has been reported to possess various biological properties. In the present study, we investigated the neuroprotective mechanisms of citronellol against rotenone induced neurod
Externí odkaz:
https://doaj.org/article/fef5ad19d94248428823debafbfa96bf
Autor:
Sheikh Azimullah, Richard L. Jayaraj, Mohamed Fizur. Nagoor Meeran, Fakhreya Y. Jalal, Abdu Adem, Shreesh Ojha, Rami Beiram
Publikováno v:
Molecules, Vol 28, Iss 2, p 685 (2023)
Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, resulting in motor deficits. The exact etiology of PD is currently unknown; however, the pathological hallmarks of PD include exces
Externí odkaz:
https://doaj.org/article/893071b66b644e2abfd80be0fc1e1354
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-24 (2019)
Abstract Stroke, the third leading cause of death and disability worldwide, is undergoing a change in perspective with the emergence of new ideas on neurodegeneration. The concept that stroke is a disorder solely of blood vessels has been expanded to
Externí odkaz:
https://doaj.org/article/de0ce355be3e4482be334671cd667f36
Autor:
Richard L. Jayaraj, Rami Beiram, Sheikh Azimullah, Nagoor Meeran M. F., Shreesh K. Ojha, Abdu Adem, Fakhreya Yousuf Jalal
Publikováno v:
Molecules, Vol 26, Iss 15, p 4627 (2021)
Parkinson’s disease is characterized by the loss of dopaminergic neurons in substantia nigra pars compacta (SNpc) and the resultant loss of dopamine in the striatum. Various studies have shown that oxidative stress and neuroinflammation plays a maj
Externí odkaz:
https://doaj.org/article/2e6c5941e7ad4cb1a0051bc5a97031bf
Autor:
Seenipandi Arunachalam, M. F. Nagoor Meeran, Sheikh Azimullah, Charu Sharma, Sameer N. Goyal, Shreesh Ojha
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 984 (2021)
The clinical usage of doxorubicin (DOX), a potent anthracycline antineoplastic drug, is often limited by its cardiotoxic effects. Thus, for improving usage of DOX, the aim of this study was to assess the cardioprotective effects of nerolidol (NERO) i
Externí odkaz:
https://doaj.org/article/73618e20a8f74cbca23428fc49830920
Autor:
Hayate Javed, Mohamed Fizur Nagoor Meeran, Sheikh Azimullah, Abdu Adem, Bassem Sadek, Shreesh Kumar Ojha
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters from synaptic vesicles in the brain. α-Syn aggregates, including Lewy bodies, are features of both sporadic and familial forms of Parkinson's disease (PD)
Externí odkaz:
https://doaj.org/article/044706ffa36d4ea3bc0f8a9433395f4e
Autor:
M.F. Nagoor Meeran, Sheikh Azimullah, M Marzouq Al Ahbabi, Niraj Kumar Jha, Vinoth-Kumar Lakshmanan, Sameer N. Goyal, Shreesh Ojha
Publikováno v:
Molecules, Vol 25, Iss 23, p 5656 (2020)
In the present study, we assessed whether nootkatone (NKT), a sesquiterpene in edible plants, can provide protection against dyslipidemia, intramyocardial lipid accumulation, and altered lipid metabolism in a rat model of myocardial infarction (MI) i
Externí odkaz:
https://doaj.org/article/fea0e56ca29e4446a99080007b361de0
Autor:
Hayate Javed, M. F. Nagoor Meeran, Sheikh Azimullah, Lujain Bader Eddin, Vivek Dhar Dwivedi, Niraj Kumar Jha, Shreesh Ojha
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1421 (2020)
Rotenone (ROT), a plant-derived pesticide is a well-known environmental neurotoxin associated with causation of Parkinson’s disease (PD). ROT impairs mitochondrial dysfunction being mitochondrial complex-I (MC-1) inhibitor and perturbs antioxidant-
Externí odkaz:
https://doaj.org/article/85e0857c07d84ec7ae5cfb1f8b750108
Autor:
Alaa Alachkar, Sheikh Azimullah, Mohamed Lotfy, Ernest Adeghate, Shreesh K. Ojha, Rami Beiram, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek
Publikováno v:
Molecules, Vol 25, Iss 7, p 1575 (2020)
Histamine H3 receptors (H3Rs) are involved in several neuropsychiatric diseases including epilepsy. Therefore, the effects of H3R antagonist E177 (5 and 10 mg/kg, intraperitoneal (i.p.)) were evaluated on the course of kindling development, kindling-
Externí odkaz:
https://doaj.org/article/4ce2c7ec25384ba198d8653948437706
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline monoterpene phenol. It is one of the most important dietary constituents in thyme species. For centuries, it has been used in traditional medicine and has been shown to
Externí odkaz:
https://doaj.org/article/cd3331b64fc940bc9be20d86f87a6e18