Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sheherazade Sebda"'
Autor:
Xavier Leleu, Claude Preudhomme, Bruno Quesnel, Catherine Roche-Lestienne, Sabine Tricot, Stéphanie Guidez, Cécile Tomowiak, Loic Renaud, Charles Herbaux, Morgane Nudel, Olivier Nibourel, Sheherazade Sebda, Sandrine Geffroy, Emmanuelle Doye, Aurélie Caillault-Venet, Aline Renneville, Elisabeth Bertrand, Christophe Roumier, Stéphanie Poulain
Purpose: TP53 is a tumor-suppressor gene that functions as a regulator influencing cellular responses to DNA damage, and TP53 alterations are associated with pejorative outcome in most B-lymphoid disorders. Little is known regarding TP53 alteration i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdf08ff56a963c9be11d0d242b7a4b7
https://doi.org/10.1158/1078-0432.c.6525416
https://doi.org/10.1158/1078-0432.c.6525416
Autor:
Xavier Leleu, Claude Preudhomme, Bruno Quesnel, Catherine Roche-Lestienne, Sabine Tricot, Stéphanie Guidez, Cécile Tomowiak, Loic Renaud, Charles Herbaux, Morgane Nudel, Olivier Nibourel, Sheherazade Sebda, Sandrine Geffroy, Emmanuelle Doye, Aurélie Caillault-Venet, Aline Renneville, Elisabeth Bertrand, Christophe Roumier, Stéphanie Poulain
Table S1. Genomic characteristics of WM with TP53 aberration; Figure S1: Delineation of 17p minimal deleted region detected by SNP array in Waldenstrom's macroglobulinemia; Figure S2. (1) Nutlin-3a effects on WM cells. Impact of nutlin-3a (10 μM, 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7344d60b462b1922479a758060b20c72
https://doi.org/10.1158/1078-0432.22463486
https://doi.org/10.1158/1078-0432.22463486
Autor:
Marie-Océane Laguillaumie, Sofia Titah, Aurélie Guillemette, Bernadette Neve, Frederic Leprêtre, Pascaline Ségard, Faruk Azam Shaik, Dominique Collard, Jean-Claude Gerbedoen, Léa Fléchon, Lama Hasan Bou Issa, Audrey Vincent, Martin Figeac, Shéhérazade Sebda, Céline Villenet, Jérôme Kluza, William Laine, Isabelle Fournier, Jean-Pascal Gimeno, Maxence Wisztorski, Salomon Manier, Mehmet Cagatay Tarhan, Bruno Quesnel, Thierry Idziorek, Yasmine Touil
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-28 (2024)
Abstract Background Tumour dormancy, a resistance mechanism employed by cancer cells, is a significant challenge in cancer treatment, contributing to minimal residual disease (MRD) and potential relapse. Despite its clinical importance, the mechanism
Externí odkaz:
https://doaj.org/article/a30941614df749d1805f6f87c1b51f5b
Autor:
Mathilde Le Maître, Thomas Guerrier, Aurore Collet, Mehdi Derhourhi, Jean-Pascal Meneboo, Bénédicte Toussaint, Amélie Bonnefond, Céline Villenet, Shéhérazade Sebda, Antonino Bongiovanni, Meryem Tardivel, Myriam Simon, Manel Jendoubi, Blanche Daunou, Alexis Largy, Martin Figeac, Sylvain Dubucquoi, David Launay
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIn systemic sclerosis (SSc), B-cells are activated and present in the skin and lung of patients where they can interact with fibroblasts. The precise impact and mechanisms of the interaction of B-cells and fibroblasts at the tissular leve
Externí odkaz:
https://doaj.org/article/d05dfa67bc0c4a69bd80b155dab66a47
Autor:
Marie Fernandes, Brynna Hoggard, Philippe Jamme, Sonia Paget, Marie‐José Truong, Valérie Grégoire, Audrey Vinchent, Clotilde Descarpentries, Angela Morabito, Justas Stanislovas, Enoir Farage, Jean‐Pascal Meneboo, Shéhérazade Sebda, Katia Bouchekioua‐Bouzaghou, Marie Nollet, Sarah Humez, Timothy Perera, Paul Fromme, Luca Grumolato, Martin Figeac, Marie‐Christine Copin, David Tulasne, Alexis B. Cortot, Stéphanie Kermorgant, Zoulika Kherrouche
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2257-2274 (2023)
Exon skipping mutations of the MET receptor tyrosine kinase (METex14), increasingly reported in cancers, occur in 3–4% of non–small‐cell lung cancer (NSCLC). Only 50% of patients have a beneficial response to treatment with MET‐tyrosine kinas
Externí odkaz:
https://doaj.org/article/272f451e35f5414da2913aa27cf75f12
Autor:
Lucie Thorel, Pierre-Marie Morice, Hippolyte Paysant, Romane Florent, Guillaume Babin, Cécilia Thomine, Marion Perréard, Edwige Abeilard, Florence Giffard, Emilie Brotin, Christophe Denoyelle, Céline Villenet, Shéhérazade Sebda, Mélanie Briand, Florence Joly, Enora Dolivet, Didier Goux, Cécile Blanc-Fournier, Corinne Jeanne, Marie Villedieu, Matthieu Meryet-Figuiere, Martin Figeac, Laurent Poulain, Louis-Bastien Weiswald
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background In the era of personalized medicine, the establishment of preclinical models of cancer that faithfully recapitulate original tumors is essential to potentially guide clinical decisions. Methods We established 7 models [4 cell line
Externí odkaz:
https://doaj.org/article/fcc6d93e6e1648e1ac7194108ee99a59
Autor:
Emmanuel Ledoult, Manel Jendoubi, Aurore Collet, Thomas Guerrier, Alexis Largy, Silvia Speca, Solange Vivier, Fabrice Bray, Martin Figeac, Eric Hachulla, Myriam Labalette, Frédéric Leprêtre, Shéhérazade Sebda, Sébastien Sanges, Christian Rolando, Vincent Sobanski, Sylvain Dubucquoi, David Launay
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract We provide an original multi-stage approach identifying a gene signature to assess murine fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß
Externí odkaz:
https://doaj.org/article/3b929e9e55f1469f8ebd0f605909aaa3
Autor:
Alexia Mopin, Frédéric Leprêtre, Shéhérazade Sebda, Céline Villenet, Meriem Ben Khoud, Martin Figeac, Bruno Quesnel, Carine Brinster
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267508 (2022)
Acute myeloid leukemia (AML) is characterized by blocked differentiation and extensive proliferation of hematopoietic progenitors/precursors. Relapse is often observed after chemotherapy due to the presence of residual leukemic cells, which is also c
Externí odkaz:
https://doaj.org/article/31962ed8d7c4476a99e37f9943419067
Autor:
Emilie Faivre, Joana E. Coelho, Katja Zornbach, Enas Malik, Younis Baqi, Marion Schneider, Lucrezia Cellai, Kevin Carvalho, Shéhérazade Sebda, Martin Figeac, Sabiha Eddarkaoui, Raphaëlle Caillierez, Yijuang Chern, Michael Heneka, Nicolas Sergeant, Christa E. Müller, Annett Halle, Luc Buée, Luisa V. Lopes, David Blum
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Consumption of caffeine, a non-selective adenosine A2A receptor (A2AR) antagonist, reduces the risk of developing Alzheimer’s disease (AD) and mitigates both amyloid and Tau lesions in transgenic mouse models of the disease. While short-term treatm
Externí odkaz:
https://doaj.org/article/28a678928c254d56b36a2ddfc3b2ac6c