Codon optimization and co-expression of thermostable β-galactosidase and L-arabinose isomerase in lactococcus lactis for single-step production of food-grade D-tagatose

Autor: Farahat, MG, Shehata, HM, Kamel, Z

D-Tagatose is a promising low-calorie sucrose substitute having prebiotic properties. In this study, biosynthesis of D-tagatose was achieved by constructing and expressing a polycistronic plasmid encoding codon-optimized thermostable β-galactosidase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::06845ffb5f4c71f8fd420d52be1be699
https://zenodo.org/record/4458878

Immunomodulatory effects and improved outcomes with cisplatin- versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer.

Autor: Galsky MD; Division of Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: matthew.galsky@mssm.edu., Guan X; Genentech Inc., South San Francisco, CA 94080, USA., Rishipathak D; Genentech Inc., South San Francisco, CA 94080, USA., Rapaport AS; Genentech Inc., South San Francisco, CA 94080, USA., Shehata HM; Genentech Inc., South San Francisco, CA 94080, USA., Banchereau R; Genentech Inc., South San Francisco, CA 94080, USA., Yuen K; Genentech Inc., South San Francisco, CA 94080, USA., Varfolomeev E; Genentech Inc., South San Francisco, CA 94080, USA., Hu R; Genentech Inc., South San Francisco, CA 94080, USA., Han CJ; Genentech Inc., South San Francisco, CA 94080, USA., Li H; Hoffmann-La Roche Ltd, Mississauga, ON, Canada., Liang Y; Genentech Inc., South San Francisco, CA 94080, USA., Vucic D; Genentech Inc., South San Francisco, CA 94080, USA., Wang L; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; GeneDx, Stamford, CT, USA., Zhu J; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; GeneDx, Stamford, CT, USA., Yu H; GeneDx, Stamford, CT, USA., Herbst RH; Immunai, New York, NY, USA., Hajaj E; Immunai, New York, NY, USA., Kiner E; Immunai, New York, NY, USA., Bamias A; National and Kapodistrian University of Athens, Athens, Greece., De Santis M; Department of Urology, Charité - Universitätsmedizin, Berlin, Germany; Department of Urology, Medical University of Vienna, Vienna, Austria., Davis ID; Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia., Arranz JÁ; Gregorio Marañón General University Hospital, Madrid, Spain., Kikuchi E; St. Marianna University School of Medicine, Kawasaki, Japan., Bernhard S; Roche Products Ltd, Welwyn Garden City, UK., Williams P; Genentech Inc., South San Francisco, CA 94080, USA., Lee C; Roche Products Ltd, Welwyn Garden City, UK., Mellman I; Genentech Inc., South San Francisco, CA 94080, USA., Sanjabi S; Genentech Inc., South San Francisco, CA 94080, USA., Johnston R; Genentech Inc., South San Francisco, CA 94080, USA., Black PC; Vancouver Prostate Centre, University of British Columbia, Vancouver, BC, Canada., Grande E; MD Anderson Cancer Center Madrid, Madrid, Spain., Mariathasan S; Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: mariathasan.sanjeev@gene.com.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2024 Feb 20; Vol. 5 (2), pp. 101393. Date of Electronic Publication: 2024 Jan 26.

miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival.

Autor: Gagnon JD; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Kageyama R; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Shehata HM; Virology and Immunology, Gladstone Institutes, San Francisco, CA 94158, USA., Fassett MS; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA., Mar DJ; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Wigton EJ; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Johansson K; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Litterman AJ; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Odorizzi P; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Simeonov D; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA., Laidlaw BJ; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA., Panduro M; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Patel S; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA., Jeker LT; Diabetes Center and Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA., Feeney ME; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., McManus MT; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA., Marson A; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Matloubian M; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Sanjabi S; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Virology and Immunology, Gladstone Institutes, San Francisco, CA 94158, USA., Ansel KM; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: mark.ansel@ucsf.edu.

Publikováno v: Cell reports [Cell Rep] 2019 Aug 20; Vol. 28 (8), pp. 2169-2181.e4.

Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections.

Autor: Shehata HM; Virology and Immunology, Gladstone Institutes, San Francisco, CA, United States., Murphy AJ; Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Lee MKS; Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Gardiner CM; School of Biochemistry and Immunology, Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin, Ireland., Crowe SM; Centre for Biomedical Research, Burnet Institute, Melbourne, VIC, Australia.; Department of Infectious Diseases, Monash University, Melbourne, VIC, Australia., Sanjabi S; Virology and Immunology, Gladstone Institutes, San Francisco, CA, United States., Finlay DK; School of Biochemistry and Immunology, Trinity College Dublin, Trinity Biomedical Sciences Institute, Dublin, Ireland., Palmer CS; Centre for Biomedical Research, Burnet Institute, Melbourne, VIC, Australia.; Department of Infectious Diseases, Monash University, Melbourne, VIC, Australia.; Department of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, Australia.

Publikováno v: Frontiers in immunology [Front Immunol] 2017 Oct 16; Vol. 8, pp. 1311. Date of Electronic Publication: 2017 Oct 16 (Print Publication: 2017).

The aged nonhematopoietic environment impairs natural killer cell maturation and function.

Autor: Shehata HM; Division of Immunobiology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and the University of Cincinnati, Cincinnati, OH, 45229, USA., Hoebe K, Chougnet CA

Publikováno v: Aging cell [Aging Cell] 2015 Apr; Vol. 14 (2), pp. 191-9. Date of Electronic Publication: 2015 Feb 09.