Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Sheh Yi Sheu"'
Publikováno v:
Advanced Intelligent Systems, Vol 3, Iss 7, Pp n/a-n/a (2021)
Quantum computers (QCs) adopt an n‐state quantum mechanical system to manipulate the superposition state. However, molecular transistors are not used to build up the quantum logic gate. Herein, it is demonstrated that DNA, RNA, and protein are prom
Externí odkaz:
https://doaj.org/article/3c66a7c92dda4f788629d3b505492304
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 51, Iss 4, Pp 478-484 (2018)
Background: Der f 7 and Der p 7 are important house dust mite allergens. An IgE-binding inhibition monoclonal antibody WH9 reacts ten folds stronger against Der p 7 than to Der f 7. The purpose of this study is to identify the antigenic determinant(s
Externí odkaz:
https://doaj.org/article/f632c245f2924ed7bc38d80b4de725d1
Publikováno v:
International Journal of Biological Macromolecules. 191:230-242
G-quadruplexes have become attractive drug targets in cancer therapy. However, due to the polymorphism of G-quadruplex structures, it is difficult to experimentally verify the relevant structures of multiple intermediates and transition states in dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b6994827c6d109f66fcb64a1d116da
https://doi.org/10.1016/j.ijbiomac.2021.09.057
https://doi.org/10.1016/j.ijbiomac.2021.09.057
Autor:
Ning Deng, Yun-Yun Wu, Yanan Feng, Wen-Chieh Hsieh, Jen-Shin Song, Yu-Shiuan Lin, Ya-Hsien Tseng, Wan-Jhu Liao, Yi-Fan Chu, Yu-Cheng Liu, En-Cheng Chang, Chia-Rung Liu, Sheh-Yi Sheu, Ming-Tsan Su, Hung-Chih Kuo, Stanley N. Cohen, Tzu-Hao Cheng
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Earlier work has shown that siRNA-mediated reduction of the SUPT4H or SUPT5H proteins, which interact to form the DSIF complex and facilitate transcript elongation by RNA polymerase II (RNAPII), can decrease expression of mutant gene alleles containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9697f58c0a4f89709daec52505070a
https://doi.org/10.1073/pnas.2204779119
https://doi.org/10.1073/pnas.2204779119
Publikováno v:
Advanced Intelligent Systems, Vol 3, Iss 7, Pp n/a-n/a (2021)
Quantum computers (QCs) adopt an n‐state quantum mechanical system to manipulate the superposition state. However, molecular transistors are not used to build up the quantum logic gate. Herein, it is demonstrated that DNA, RNA, and protein are prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7494f3dfb7a643df5804d05cfa0508
https://doaj.org/article/3c66a7c92dda4f788629d3b505492304
https://doaj.org/article/3c66a7c92dda4f788629d3b505492304
Publikováno v:
The Journal of Physical Chemistry B. 123:6917-6932
Hydration water serves as a microscopic manifestation of structural stability and functions of biomolecules. To develop bio-nanomaterials in applications, it is important to study how the surface topography and heterogeneity of biomolecules result in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3a4dac7840f4989d3bae5166b49e91
https://doi.org/10.1021/acs.jpcb.9b03734
https://doi.org/10.1021/acs.jpcb.9b03734
Autor:
Viktor M. Rozenbaum, Sheng Hsien Lin, Dah Yen Yang, Sheh-Yi Sheu, I. V. Shapochkina, Leonid I. Trakhtenberg
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 514:71-78
We consider the overdamped motion of a Brownian particle in an asymmetric spatially periodic potential which fluctuates periodically in time, under assumption of finite duration of the relaxation response of the system on deterministic dichotomous fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd43942837b91c20252e942e21b634d6
https://doi.org/10.1016/j.physa.2018.09.039
https://doi.org/10.1016/j.physa.2018.09.039
This Supporting Information includes the extended description of the superposition state of the asymmetric double-well system in vacuum system and in solution, truth tables for the residue pairs and their corresponding quantum logic gates, and figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4d9c37df9911d110f868132b8c678f
https://doi.org/10.22541/au.161462308.84219902/v1
https://doi.org/10.22541/au.161462308.84219902/v1
Autor:
Hsiao-Yun Tai, Jia-Kai Zhou, Hong Chou, Ming F Tam, Yu-Sen Chen, Sheh-Yi Sheu, Horng-Der Shen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71269 (2013)
Der p 7 is an important house dust mite allergen. However, antigenic determinants of Der p 7 are largely unknown. The purpose of this study is to analyze the determinants of Der p 7 and determine the structural basis of interactions between Der p 7 a
Externí odkaz:
https://doaj.org/article/eec85af3e87f454fb1d5e36f692f6de3
BackgroundTraditional drug development is time-consuming and expensive, while computer-aided drug repositioning can improve efficiency and productivity. In this study, we proposed a machine learning pipeline to predict the binding interaction between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c58b4cc9bcbe3e4451f82e79d9a48d
https://doi.org/10.1101/2020.07.29.218826
https://doi.org/10.1101/2020.07.29.218826