Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shefali Talwar"'
Autor:
Ryan von Kleeck, Paola Castagnino, Emilia Roberts, Shefali Talwar, Giovanni Ferrari, Richard K. Assoian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Children with Hutchinson–Gilford Progeria Syndrome (HGPS) suffer from multiple cardiovascular pathologies due to the expression of progerin, a mutant form of the nuclear envelope protein Lamin A. Progerin expression has a dramatic effect o
Externí odkaz:
https://doaj.org/article/65657194454f4770992d55005dc6e736
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109019- (2021)
Summary: Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation correlate with stiffness of the arterial extracellular matrix (ECM), but causal relatio
Externí odkaz:
https://doaj.org/article/d512757883aa44eaa80868b9390f8228
Autor:
Soumya Gupta, Nimi Marcel, Shefali Talwar, Megha Garg, Indulaxmi R, Lakshmi R Perumalsamy, Apurva Sarin, G V Shivashankar
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43718 (2012)
Cellular differentiation programs are accompanied by large-scale changes in nuclear organization and gene expression. In this context, accompanying transitions in chromatin assembly that facilitates changes in gene expression and cell behavior in a d
Externí odkaz:
https://doaj.org/article/29e79660bab74c49ad89859806a1c9c4
Autor:
Emilia Roberts, Richard K. Assoian, Paola Castagnino, Shefali Talwar, Giovanni Ferrari, Ryan A. von Kleeck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Children with Hutchinson–Gilford Progeria Syndrome (HGPS) suffer from multiple cardiovascular pathologies due to the expression of progerin, a mutant form of the nuclear envelope protein Lamin A. Progerin expression has a dramatic effect on arteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e832c7dd49e27b925575c52d7bce66
https://doaj.org/article/65657194454f4770992d55005dc6e736
https://doaj.org/article/65657194454f4770992d55005dc6e736
Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility
Autor:
Sreeja B. Asokan, Tatyana Svitkina, Richard K. Assoian, James E. Bear, Shefali Talwar, Maria S. Shutova
Publikováno v:
The Journal of Cell Biology
Copolymerization of nonmuscle myosins IIA and IIB followed by their differential turnover in stress fibers leads to self-sorting of IIA and IIB along the front–rear axis of the cell, thus producing a polarized actin cytoskeleton.
Nonmuscle myo
Nonmuscle myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fee55d744cab94d3409c973d14938b
https://doi.org/10.1083/jcb.201705167
https://doi.org/10.1083/jcb.201705167
Publikováno v:
Cell reports
Cell Reports, Vol 35, Iss 3, Pp 109019-(2021)
Cell Reports, Vol 35, Iss 3, Pp 109019-(2021)
SUMMARY Reversible differentiation of vascular smooth muscle cells (VSMCs) plays a critical role in vascular biology and disease. Changes in VSMC differentiation correlate with stiffness of the arterial extracellular matrix (ECM), but causal relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33eaadd515bbc0bac60011cb1a9f2fc2
https://doi.org/10.1016/j.celrep.2021.109019
https://doi.org/10.1016/j.celrep.2021.109019
Autor:
Mallika Nagarajan, Shovamayee Maharana, Yejun Wang, Shefali Talwar, K. Venkatesan Iyer, Nikhil Jain, G. V. Shivashankar
Publikováno v:
Methods (San Diego, Calif.). 123
In this article, we summarize current findings for the emergence of biophysical properties such as nuclear stiffness, chromatin compaction, chromosome positioning, and chromosome intermingling during stem cell differentiation, which eventually correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::520d0518f86c5d98e829b7169b804316
https://pubmed.ncbi.nlm.nih.gov/28554525
https://pubmed.ncbi.nlm.nih.gov/28554525
Publikováno v:
Biophysical Journal. 104(3):553-564
Stem cells integrate signals from the microenvironment to generate lineage-specific gene expression programs upon differentiation. Undifferentiated cell nuclei are easily deformable, with an active transcriptome, whereas differentiated cells have sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f083c86a8e7debf4c62a7108d4b01bb3
Publikováno v:
Biophysical Journal. 96:3832-3839
Cellular differentiation and developmental programs require changing patterns of gene expression. Recent experiments have revealed that chromatin organization is highly dynamic within living cells, suggesting possible mechanisms to alter gene express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62b40c6419ef8d119cbc0bff80a12ed
https://doi.org/10.1016/j.bpj.2008.11.075
https://doi.org/10.1016/j.bpj.2008.11.075
Autor:
Sameena S. Khan, Robert L. Danner, Debra Reda, Jennifer J. Barb, Shefali Talwar, James H. Shelhamer, Margaret Tropea, Anthony F. Suffredini, Carolea Logun, Peter J. Munson, Carmen Fiuza, Anadel Pilar Cintron
Publikováno v:
Physiological Genomics. 25:203-215
To define gene expression profiles that occur during the initial activation of human innate immunity, we administered intravenous endotoxin ( n = 8) or saline ( n = 4) to healthy subjects and hybridized RNA from blood mononuclear cells (0, 0.5, 6, 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ba7325fd16ef22c1a05ba063377dd3
https://doi.org/10.1152/physiolgenomics.00192.2005
https://doi.org/10.1152/physiolgenomics.00192.2005