Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shefalee K. Bhavsar"'
Autor:
Shefalee K. Bhavsar, Yogesh Singh, Piyush Sharma, Vishal Khairnar, Zohreh Hosseinzadeh, Shaqiu Zhang, Monica Palmada, Ivan Sabolic, Hermann Koepsell, Karl S. Lang, Philipp A. Lang, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 3, Pp 1209-1228 (2016)
Background: Similar to tumor cells, activated T-lymphocytes generate ATP mainly by glycolytic degradation of glucose. Lymphocyte glucose uptake involves non-concentrative glucose carriers of the GLUT family. In contrast to GLUT isoforms, Na+-coupled
Externí odkaz:
https://doaj.org/article/9a40af3fa0af40ef8b61c68467416474
Publikováno v:
Kidney & Blood Pressure Research, Vol 37, Iss 4-5, Pp 514-520 (2013)
Background/Aims: The Janus kinase 3 JAK3 participates in the signaling of immune cells. Lack of JAK3 triggers inflammatory bowel disease, which in turn has been shown to affect intestinal activity of the epithelial Na+ channel ENaC and thus colonic s
Externí odkaz:
https://doaj.org/article/7a859520e8bd471d9279c26b1cde505e
Autor:
Shefalee K. Bhavsar, Sebastian Schmidt, Diwakar Bobbala, Meerim K. Nurbaeva, Zohreh Hosseinzadeh, Katja Merches, Abul Fajol, Jan Wilmes, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 3, Pp 687-698 (2013)
Background/Aims: T-lymphocyte activation and function critically depends on Ca2+ signaling, which is regulated by store operated Ca2+ entry (SOCE). Human and mouse T lymphocytes express AMP activated kinase AMPKα1, which is rapidly activated followi
Externí odkaz:
https://doaj.org/article/a4cebac5b66b47a09c2ecc66cb8b6cb0
Autor:
Zohreh Hosseinzadeh, Luo Dong, Shefalee K. Bhavsar, Jamshed Warsi, Ahmad Almilaji, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 31, Iss 4-5, Pp 673-682 (2013)
Background/Aims: Janus-activated kinase-2 JAK2 participates in the signaling of several hormones including growth hormone, fosters tumor growth and modifies the activity of several Na+ coupled nutrient transporters. Peptide uptake into intestinal and
Externí odkaz:
https://doaj.org/article/f2478c1a1fa2418fbcbb2a63bff88cb5
Autor:
Vishal Khairnar, Philipp A. Lang, Shaqiu Zhang, Hermann Koepsell, Zohreh Hosseinzadeh, Piyush Sharma, Shefalee K. Bhavsar, Yogesh Singh, Florian Lang, Karl S. Lang, Ivan Sabolić, Monica Palmada
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 3, Pp 1209-1228 (2016)
Background: Similar to tumor cells, activated T-lymphocytes generate ATP mainly by glycolytic degradation of glucose. Lymphocyte glucose uptake involves non-concentrative glucose carriers of the GLUT family. In contrast to GLUT isoforms, Na+-coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6577d2247c7faa27ffcd83abcfa544d5
https://doi.org/10.1159/000447827
https://doi.org/10.1159/000447827
Autor:
Reinhard Kandolf, Michael Föller, Bingbing Zhang, Shefalee K. Bhavsar, Abul Fajol, Zohreh Hosseinzadeh, Ana Velic, Florian Lang, Christoph Daniel, C.-Thomas Bock, Kerstin Amann, Anja T. Umbach, Bernd J. Pichler
Publikováno v:
Kidney International. 87:728-737
Calcitriol, a powerful regulator of phosphate metabolism and immune response, is generated by 25-hydroxyvitamin D 1α-hydroxylase in the kidney and macrophages. Renal 1α-hydroxylase expression is suppressed by Klotho and FGF23, the expression of whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35aed06d12d35ab0bcbb9151f21e874
https://doi.org/10.1038/ki.2014.371
https://doi.org/10.1038/ki.2014.371
Autor:
Guoxing Liu, Zohreh Hosseinzadeh, Tatsiana Pakladok, Ahmad Almilaji, Ekaterina Shumilina, Florian Lang, Peter Ruth, Sabina Honisch, Shefalee K. Bhavsar
Publikováno v:
American Journal of Physiology-Cell Physiology. 306:C1041-C1049
The iberiotoxin-sensitive large conductance voltage- and Ca2+-activated potassium (BK) channels (maxi-K+-channels) hyperpolarize the cell membrane thus supporting Ca2+entry through Ca2+-release activated Ca2+channels. Janus kinase-2 (JAK2) has been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4aea0da60f895f5fab1498722e76e1f
https://doi.org/10.1152/ajpcell.00209.2013
https://doi.org/10.1152/ajpcell.00209.2013
Autor:
Luo Dong, Florian Lang, Ekaterina Shumilina, Tatsiana Pakladok, Anja T. Umbach, Zohreh Hosseinzadeh, Jamshed Warsi, Shefalee K. Bhavsar
Publikováno v:
The Journal of Membrane Biology. 246:885-892
The tyrosine kinase Janus kinase 3 (JAK3) contributes to signaling regulating the proliferation and apoptosis of lymphocytes and tumor cells. Replacement of lysine by alanine in the catalytic subunit yields the inactive (K851A)JAK3 mutant that underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14539b5cee335ed20a26911e83edebac
https://doi.org/10.1007/s00232-013-9582-3
https://doi.org/10.1007/s00232-013-9582-3
Autor:
Diwakar Bobbala, Abul Fajol, Florian Lang, Jan Wilmes, Sebastian Schmidt, Meerim K. Nurbaeva, Katja Merches, Zohreh Hosseinzadeh, Shefalee K. Bhavsar
Publikováno v:
Cellular Physiology and Biochemistry. 32:687-698
Background/Aims: T-lymphocyte activation and function critically depends on Ca2+ signaling, which is regulated by store operated Ca2+ entry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b2532a25af9f90243e50c1fd289c143
https://doi.org/10.1159/000354472
https://doi.org/10.1159/000354472
Publikováno v:
Biochemical and Biophysical Research Communications. 420:172-177
Janus-activated kinase-2 JAK2 is activated by hyperosmotic shock and modifies the activity of several Na(+) coupled transporters. Carriers up-regulated by osmotic shock include the Na(+) coupled osmolyte transporter BGT1 (betaine/GABA transporter 1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b14646e5543c5738b24955c277f6375
https://doi.org/10.1016/j.bbrc.2012.02.137
https://doi.org/10.1016/j.bbrc.2012.02.137