Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sheetal Bodhankar"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55984 (2013)
Mycoplasmas cause chronic respiratory diseases in animals and humans, and to date, development of vaccines have been problematic. Using a murine model of mycoplasma pneumonia, lymphocyte responses, specifically T cells, were shown to confer protectio
Externí odkaz:
https://doaj.org/article/c1dea3c9d19849498cf422e51475133d
Autor:
Halina Offner, Andrew Lapato, Julie A. Saugstad, Yingxin Chen, Abby L. Dotson, Arthur A. Vandenbark, Sheetal Bodhankar, Jianming Wang
Publikováno v:
Stroke. 46:2926-2934
Background and Purpose— Both pathogenic and regulatory immune processes are involved in the middle cerebral artery occlusion (MCAO) model of experimental stroke, including interactions involving the programmed death 1 (PD-1) receptor and its 2 liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1648c47a2f9b53b75ae15958a9c15686
https://doi.org/10.1161/strokeaha.115.010592
https://doi.org/10.1161/strokeaha.115.010592
IL-10 producing B cells partially restore E2-mediated protection against EAE in PD-L1 deficient mice
Autor:
Halina Offner, Jun Zhang, Sheetal Bodhankar, Andrew Lapato, Arthur A. Vandenbark, Gil Benedek
Publikováno v:
Journal of Neuroimmunology. 285:129-136
Women with multiple sclerosis (MS) often experience clinical improvement during pregnancy, indicating that sex hormones might have therapeutic effects in MS. Our previous studies have demonstrated that B cells and PD-L1 are crucial for E2 (17β-estra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a34545611fa625cb3675bd8ebad54bc
https://doi.org/10.1016/j.jneuroim.2015.06.002
https://doi.org/10.1016/j.jneuroim.2015.06.002
Publikováno v:
Metabolic Brain Disease. 30:1117-1127
Clinical improvement during pregnancy in multiple sclerosis (MS) patients suggests that sex hormones exert potent regulatory effects on autoimmune function. Our previous studies demonstrated that estrogen- (17β-estradiol; E2) mediated protection aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb0ad86c51e962a48afb170b52bed7b
https://doi.org/10.1007/s11011-015-9661-5
https://doi.org/10.1007/s11011-015-9661-5
Autor:
Jun Zhang, Ha Nguyen, Kelley Jordan, Gail Kent, Gil Benedek, Halina Offner, Dustin Manning, Arthur A. Vandenbark, Sheetal Bodhankar
Publikováno v:
Journal of neuroimmunology. 293
Sex hormones promote immunoregulatory effects on multiple sclerosis. The current study evaluated estrogen effects on regulatory B cells and resident CNS microglia during experimental autoimmune encephalomyelitis (EAE). Herein, we demonstrate an estro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8462de2d50037ffd0b3ccf9d7626a4a7
https://pubmed.ncbi.nlm.nih.gov/27049561
https://pubmed.ncbi.nlm.nih.gov/27049561
Autor:
Halina Offner, Nabil J. Alkayed, Arthur A. Vandenbark, Yingxin Chen, Sheetal Bodhankar, Stephanie J. Murphy
Publikováno v:
Metabolic Brain Disease. 27:487-493
Recent evidence emphasizes B-cells as a major regulatory cell type that plays an important role in limiting the pathogenic effects of ischemic stroke. The aim of the current study was to extend this initial observation to specifically examine the inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31da0c7f4b10655e0fb1b7e4d08a35e2
https://doi.org/10.1007/s11011-012-9317-7
https://doi.org/10.1007/s11011-012-9317-7
Autor:
Sheetal Bodhankar, Halina Offner
Publikováno v:
Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry. 11:262-274
A major focus of our laboratory has been an in-depth evaluation as to how estrogens exert a pronounced protective effect on clinical and histological disease in the animal model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4181d73a45f70b781a945802abcd5516
https://doi.org/10.2174/1871522211108040262
https://doi.org/10.2174/1871522211108040262
Publikováno v:
European Journal of Immunology. 41:1165-1175
Increased remissions in multiple sclerosis (MS) during pregnancy suggest that elevated levels of sex steroids exert immunoregulatory activity. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c647206236e07aaf6dc6fa197e133d84
https://doi.org/10.1002/eji.201040992
https://doi.org/10.1002/eji.201040992
Publikováno v:
The Journal of Infectious Diseases. 202:39-51
For vaccine development, it is critical to understand the regulatory mechanisms determining resistance and immunopathology against mycoplasma respiratory diseases. The present study evaluated the contribution of the polarizing cytokines interferon ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45a46e60e993c8611d7dac687c7c9df
https://doi.org/10.1086/653121
https://doi.org/10.1086/653121
Publikováno v:
The Journal of Immunology. 183:2622-2631
The purpose of the present study was to determine the impact of NK cells on the development of protective adaptive immunity in response to nasal-pulmonary immunization against mycoplasma. Depletion of NK cells before nasal-pulmonary immunization enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9500859a700428e7d86e05fd55136ed
https://doi.org/10.4049/jimmunol.0802180
https://doi.org/10.4049/jimmunol.0802180