Zobrazeno 1 - 10 of 35 pro vyhledávání: '"Sheetal A. Mitra"'
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Supplementary Tables from TDP1 and PARP1 Deficiency Are Cytotoxic to Rhabdomyosarcoma Cells
Autor: Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Supplementary Tables - PDF file 330K, Supplementary Table 1. Nucleotide sequences for oligonucleotides, TDP1 siRNAs and TDP1 shRNAs used. Supplementary Table 2. Comparison of Tdp1 expression between noncancerous skeletal muscle and RMS subtypes. Supp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129299397b3c99d98886e8e330400506
https://doi.org/10.1158/1541-7786.22509630
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3
Data from TDP1 and PARP1 Deficiency Are Cytotoxic to Rhabdomyosarcoma Cells
Autor: Cornelius F. Boerkoel, Catherine J. Pallen, Mason Bond, Timothy J. Triche, Samuel Aparicio, Gulisa Turashvili, Maureen J. O'Sullivan, Patrick C.W. Wong, Guobin Sun, Kunho Choi, Nichola Osborne, Miraj Chowdhury, Sheetal A. Mitra, Cheryl Walton, Hok Khim Fam
Rhabdomyosarcoma is the most common soft tissue sarcoma in children. Metastatic rhabdomyosarcoma in children has a 5-year event-free survival rate of TDP1 or inhibition of poly(ADP-ribose) polymerase-1 (PARP-1), an enzyme in the same complex as TDP1,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3580accf9db3347642bf13a8aaae7bb1
https://doi.org/10.1158/1541-7786.c.6539355
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5
Abstract 5170: Coding and non-coding gene meta-features predict outcome in pediatric rhabdomyosarcomas
Autor: Anirban P. Mitra, Sheetal A. Mitra, Jonathan D. Buckley, Stephen X. Skapek, Douglas S. Hawkins, Timothy J. Triche
Publikováno v: Cancer Research. 82:5170-5170
INTRODUCTION: Pediatric rhabdomyosarcoma (RMS) has varying outcomes, particularly in intermediate-risk disease (IR-RMS) due to the limited ability of clinical staging to accurately risk-stratify a large proportion of patients. This study aimed to ide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abb25e6332900a0dbe58d2c893386dcc
https://doi.org/10.1158/1538-7445.am2022-5170
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6
Molecular mechanisms of Guadecitabine induced FGFR4 down regulation in alveolar rhabdomyosarcomas
Autor: Sheetal A. Mitra, Yong-Hwee Eddie Loh, Zesheng Wan, Xiaogang Hou, Katherine K. Slemmons, Emad Darvishi, Lee J. Helman, Jean Hugues Parmentier
Publikováno v: Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 7, Pp 274-282 (2020)
Fibroblast growth factor receptor 4 (FGFR4) aberrant expression and activity have been linked to the pathogenesis of a variety of cancers including rhabdomyosarcomas (RMS). We found that treatment of alveolar rhabdomyosarcoma (aRMS) cells with Guadec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbb00a4835ceb41f1ff2fb3518bbe12
https://pubmed.ncbi.nlm.nih.gov/32464274
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7
Akademický článek
A Central Role for Long Non-coding RNA in Cancer
Autor: Sheetal A Mitra, Anirban P Mitra, Timothy J Triche
Publikováno v: Frontiers in Genetics, Vol 3 (2012)
Long non-coding RNAs have been shown to regulate important biological processes that support normal cellular functions. Aberrant regulation of these essential functions can promote tumor development. In this review, we underscore the importance of th
Externí odkaz: https://doaj.org/article/26de7a89f51944f9a4e45c04a49af584
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8
MP63-12 EMPLOYMENT OF A METAGENOMIC APPROACH TO IDENTIFY PUTATIVE PROGNOSTIC BIOMARKERS THAT PERTURB THE CELLULAR CIRCUITRY IN BLADDER CANCER
Autor: Siamak Daneshmand, Anirban P. Mitra, Sheetal A. Mitra
Publikováno v: Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Profiling studies have identified several biomarker panels associated with bladder cancer outcomes. However, there is marginal overlap between such panels, thereby limit...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c6a0487f6993c30128d10a4e2f54d20
https://doi.org/10.1097/01.ju.0000556855.95113.82
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Use of Artificial Intelligence and Machine Learning Algorithms with Gene Expression Profiling to Predict Recurrent Nonmuscle Invasive Urothelial Carcinoma of the Bladder
Autor: Kenneth Steven, Anirban P. Mitra, David W. Fry, Richard J. Cote, Georg Bartsch, William P. Worzel, Arpit A. Almal, Sheetal A. Mitra, Donald G. Skinner, Peter F. Lenehan
Publikováno v: Journal of Urology. 195:493-498
Due to the high recurrence risk of nonmuscle invasive urothelial carcinoma it is crucial to distinguish patients at high risk from those with indolent disease. In this study we used a machine learning algorithm to identify the genes in patients with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e7a36027ad3c785a68af86e6f6edfef
https://doi.org/10.1016/j.juro.2015.09.090
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Abstract 4499: Genomic editing of EWS-FLI1 and its targets, and its therapeutic potential in treatment of Ewing sarcoma
Autor: Veronica Magnon, Sheetal A. Mitra, Namritha Ravinder, Jon Nagy, Timothy J. Triche
Publikováno v: Cancer Research. 79:4499-4499
Ewing sarcoma (ES) is an aggressive bone and soft tissue tumor. These tumors have a low mutational burden and are mainly driven by chimeric transcription factor, EWS-FLI1 or equivalent fusion gene. Tumor dependency on EWS-FLI1 makes it an ideal thera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c03f82c80284d5b9d47a9d272d0e579a
https://doi.org/10.1158/1538-7445.am2019-4499
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