Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sheetal A Thakur"'
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26463 (2011)
During viral infections, single- and double-stranded RNA (ssRNA and dsRNA) are recognized by the host and induce innate immune responses. The cellular enzyme ADAR-1 (adenosine deaminase acting on RNA-1) activation in virally infected cells leads to p
Externí odkaz:
https://doaj.org/article/9c62b5faa4eb43f89f3ff14f7d7a526a
Publikováno v:
Toxicological Sciences. 108:462-471
Chronic exposure to crystalline silica can lead to the development of silicosis, an irreversible, inflammatory and fibrotic pulmonary disease. Although, previous studies established the macrophage receptor with collagenous structure (MARCO) as an imp
Publikováno v:
Journal of Immunotoxicology. 5:151-157
Both immune and non-immune cells express an extensive array of scavenger receptors that bind a variety of ligands including bacterial cell-wall components and lipoproteins. Over the past several years, significant advances have been made in elucidati
Alveolar macrophages (AM) in the lung have been documented to play pivotal roles in inflammation and fibrosis (silicosis) following inhalation of crystalline silica (CSiO(2)). In contrast, exposure to either titanium dioxide (TiO(2)) or amorphous sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a96aada4b27e07ac5749b6320dc5c86
https://europepmc.org/articles/PMC2735421/
https://europepmc.org/articles/PMC2735421/
Inhalation of the crystalline form of silica is associated with a variety of pathologies from acute lung inflammation to silicosis, in addition to autoimmune disorders and cancer. Basic science researchers looking at the mechanisms involved with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b34475a90a34068ec8cb1d892ab8579
https://europepmc.org/articles/PMC2680955/
https://europepmc.org/articles/PMC2680955/
Publikováno v:
The Journal of biological chemistry. 281(45)
Scavenger receptors (SR), on the surface of the macrophage, appear to be responsible for silica uptake and cell death signaling in the macrophage. The purpose of this study was to isolate which SRs (macrophage receptor with collagenous structure (MAR
Publikováno v:
Toxicological Sciences; Apr2009, Vol. 108 Issue 2, p462-471, 10p
Publikováno v:
Toxicological Sciences; Jan2009, Vol. 107 Issue 1, p238-238, 1p