Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sheeny K. Lan Levengood"'
Publikováno v:
ACS Applied Bio Materials. 2:1088-1097
The propensity of glioblastoma multiforme (GBM) cells to migrate along white matter tracts and blood vessels suggests that topographical cues associated with brain parenchyma greatly influence GBM motility and invasion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a49de4408c472781d1c4a031c82b22f
https://doi.org/10.1021/acsabm.8b00704
https://doi.org/10.1021/acsabm.8b00704
Publikováno v:
Journal of Materials Chemistry B. 5:1822-1833
Dermal wounds, both acute and chronic, represent a significant clinical challenge and therefore the development of novel biomaterial-based skin substitutes to promote skin repair is essential. Nanofibers have garnered attention as materials to promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21757ffc6333795fce0a523d05785077
https://doi.org/10.1039/c6tb03223k
https://doi.org/10.1039/c6tb03223k
Autor:
Ching T Tsao, Jialu Sun, Miqin Zhang, Fei-Chien Chang, Shawn Swanson, Sheeny K. Lan Levengood, Ariane E. Erickson
Publikováno v:
Biomedical Microdevices. 21
Prolonged osteochondral tissue damage can result in osteoarthritis and decreased quality of life. Multiphasic scaffolds, where different layers model different microenvironments, are a promising treatment approach, yet stable joining between layers d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f14f7771985fd87dd071ac8612dd025
https://doi.org/10.1007/s10544-019-0373-1
https://doi.org/10.1007/s10544-019-0373-1
Autor:
Richard G. Ellenbogen, Sheeny K. Lan Levengood, Miqin Zhang, Ariane E. Erickson, Forrest M. Kievit, Kui Wang
Publikováno v:
Biomaterials Science. 4:610-613
Better prediction of in vivo drug efficacy using in vitro models should greatly improve in vivo success. Here we utilize 3D highly porous chitosan-alginate complex scaffolds to probe how various components of the glioblastoma microenvironment includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f33feca42f33debd320358430671035
https://doi.org/10.1039/c5bm00514k
https://doi.org/10.1039/c5bm00514k
Autor:
Nick Cho, Sheeny K. Lan Levengood, Miqin Zhang, John S. Yu, Everet Wang, Likai Chen, Fei-Chien Chang
Two-dimensional monolayer cell cultures are routinely utilized for preclinical cancer drug screening, but the results often do not translate well when drugs are tested in vivo. To address this limitation, a biocompatible chitosan-PEG hydrogel (CSPG g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa3103305dd9dc807a6b1ebd0921b99
https://europepmc.org/articles/PMC6703847/
https://europepmc.org/articles/PMC6703847/
Publikováno v:
Advanced healthcare materials. 7(15)
The invasive and recurrent nature of glioblastoma multiforme (GBM) is linked to a small subpopulation of cancer cells, which are self-renewing, resistant to standard treatment regimens, and induce formation of new tumors. Matrix stiffness is implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dcd15199c294cd3ecbd8cd137bcf8b7
https://pubmed.ncbi.nlm.nih.gov/29893067
https://pubmed.ncbi.nlm.nih.gov/29893067
Autor:
Miqin Zhang, Mengying Zhang, Sheeny K. Lan Levengood, Fei Chien Chang, Ching Ting Tsao, Anqi Lin
Publikováno v:
Polymers, Vol 8, Iss 4, p 112 (2016)
Polymers; Volume 8; Issue 4; Pages: 112
Polymers
Polymers; Volume 8; Issue 4; Pages: 112
Polymers
Mechanical properties of the extracellular matrix have a profound effect on the behavior of anchorage-dependent cells. However, the mechanisms that define the effects of matrix stiffness on cell behavior remains unclear. Therefore, the development an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f700c1b34bc9b7e63ff69ffdf0723acf
http://www.mdpi.com/2073-4360/8/4/112
http://www.mdpi.com/2073-4360/8/4/112
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 28(48)
Repair of damaged skeletal-muscle tissue is limited by the regenerative capacity of the native tissue. Current clinical approaches are not optimal for the treatment of large volumetric skeletal-muscle loss. As an alternative, tissue engineering repre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d8855622ee55b2f3c5866fc9d611a6
https://pubmed.ncbi.nlm.nih.gov/27865007
https://pubmed.ncbi.nlm.nih.gov/27865007
Autor:
Michael W. Toepke, Nicholas A. Impellitteri, Ian M. Bird, Sheeny K. Lan Levengood, William L. Murphy, Derek S. Boeldt
Publikováno v:
Advanced Healthcare Materials. 1:457-460
VEGF-binding peptide ligands are incorporated into hydrogel microspheres and reduce the amount of growth factor in solution. VEGF binding affinity is enhanced by creating ligands with a dimer structure. The spheres are able to knock down VEGF-mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59553213ff6e22e43edc38e9c2fd08fe
https://doi.org/10.1002/adhm.201200077
https://doi.org/10.1002/adhm.201200077
Autor:
James W. Checco, Kimberly J. Peterson-Kaufman, Sheeny K. Lan Levengood, Holly S. Haase, William L. Murphy, Samuel H. Gellman
Publikováno v:
Journal of the American Chemical Society. 134:7652-7655
Diverse strategies have been explored to mimic the surface displayed by an α-helical segment of a protein, with the goal of creating inhibitors of helix-mediated protein-protein interactions. Many recognition surfaces on proteins, however, are topol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca33a03ffc868990f5eeb9ab6e5c50c
https://doi.org/10.1021/ja302469a
https://doi.org/10.1021/ja302469a