Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sheene Kim"'
Autor:
David B Savage, Lanmin Zhai, Balasubramanian Ravikumar, Cheol Soo Choi, Johanna E Snaar, Amanda C McGuire, Sung-Eun Wou, Gemma Medina-Gomez, Sheene Kim, Cheryl B Bock, Dyann M Segvich, Bhavana Solanky, Dinesh Deelchand, Antonio Vidal-Puig, Nicholas J Wareham, Gerald I Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A Pederson, Peter J Roach, Stephen O'Rahilly, Anna A DePaoli-Roach
Publikováno v:
PLoS Medicine, Vol 5, Iss 12 (2008)
Externí odkaz:
https://doaj.org/article/d1e6e766999a48f0b791226f47bd8ce9
Autor:
David B Savage, Lanmin Zhai, Balasubramanian Ravikumar, Cheol Soo Choi, Johanna E Snaar, Amanda C McGuire, Sung-Eun Wou, Gemma Medina-Gomez, Sheene Kim, Cheryl B Bock, Dyann M Segvich, Bhavana Solanky, Dinesh Deelchand, Antonio Vidal-Puig, Nicholas J Wareham, Gerald I Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A Pederson, Peter J Roach, Stephen O'Rahilly, Anna A DePaoli-Roach
Publikováno v:
PLoS Medicine, Vol 5, Iss 1, p e27 (2008)
Stored glycogen is an important source of energy for skeletal muscle. Human genetic disorders primarily affecting skeletal muscle glycogen turnover are well-recognised, but rare. We previously reported that a frameshift/premature stop mutation in PPP
Externí odkaz:
https://doaj.org/article/6ce03d253c6846a6a8db7e41f2d27e2d
Autor:
Sheene Kim, Hei Sook Sul, Gary W. Cline, Cheol Soo Choi, Yuhui Wang, Yu-Jin Hwang, Young-Bum Kim, Josep A. Villena, Gerald I. Shulman
Publikováno v:
Diabetes. 57:3258-3266
OBJECTIVE—White adipose tissue is a critical regulator of whole-body glucose metabolism. Preadipocyte factor-1 (Pref-1) is a secreted protein that inhibits adipocyte differentiation, both in vitro and in vivo. In this study, we have investigated th
Autor:
Sandeep Robert Datta, Gerald I. Shulman, Jude T. Deeney, Joel Morash, Jakob D. Wikstrom, Jill K. Fisher, Chen-Yu Zhang, Barbara E. Corkey, Loren D. Walensky, Orian S. Shirihai, Stanley J. Korsmeyer, Kirsten Robertson, Sheene Kim, Susanne Neschen, Michael E. Greenberg, Nika N. Danial, Cheol Soo Choi, Bradford B. Lowell, Kenneth L. Pitter, Ameya Kulkarni, Gregory H. Bird, Anthony J.A. Molina
Publikováno v:
Nature Medicine. 14:144-153
The proapoptotic BCL-2 family member BAD resides in a glucokinase-containing complex that regulates glucose-driven mitochondrial respiration. Here, we present genetic evidence of a physiologic role for BAD in glucose-stimulated insulin secretion by b
Autor:
Gerald I. Shulman, Roberto Codella, Gary W. Cline, Ameya Kulkarni, Yu-Jin Hwang, Richard M. Reznick, Dongyan Zhang, Cheol Soo Choi, Zhen-Xiang Liu, Lutfi Abu-Elheiga, Alberto Distefano, David B. Savage, Sheene Kim, Salih J. Wakil
Publikováno v:
Proceedings of the National Academy of Sciences. 104:16480-16485
Acetyl–CoA carboxylase 2 (ACC)2 is a key regulator of mitochondrial fat oxidation. To examine the impact of ACC2 deletion on whole-body energy metabolism, we measured changes in substrate oxidation and total energy expenditure in Acc2 −/− and W
Autor:
Klaudia Polak, Sheene Kim, Jill K. Fisher, Gary W. Cline, Hu Huang, Benjamin Szlyk, Dae Ho Lee, Gerald I. Shulman, Alfredo Giménez-Cassina, Nika N. Danial, Alberto Distefano, Kirsten Robertson, Marina Godes, Muhammed A. Yildirim, Cheol Soo Choi, Ameya Kulkarni, Varman T. Samuel, Elaura Patton, Young-Bum Kim, Mayowa A. Osundiji, Luisa Garcia-Haro, Jessica Wiwczar, Elizabeth A. Lane
Publikováno v:
Cell metabolism. 19(2)
Summary The homeostatic balance of hepatic glucose utilization, storage, and production is exquisitely controlled by hormonal signals and hepatic carbon metabolism during fed and fasted states. How the liver senses extracellular glucose to cue glucos
Autor:
Gary W. Cline, Cheol Soo Choi, Pushpankur Ghoshal, Malathi Srinivasan, Sheene Kim, Mulchand S. Patel
Publikováno v:
Lipids. 45(11)
The pyruvate dehydrogenase complex (PDC) plays a critical role in lipid synthesis and glucose homeostasis in the fed and fasting states. The central role of the liver in the maintenance of glucose homeostasis has been established by studying changes
Autor:
Christoph Handschin, Cheol Soo Choi, Gary W. Cline, Yu-Jin Hwang, Richard M. Reznick, Dongyan Zhang, Zhen-Xiang Liu, Varman T. Samuel, Bruce M. Spiegelman, Alberto Distefano, Hui-Young Lee, Jiandie D. Lin, Roberto Codella, Kitt Falk Petersen, Douglas E. Befroy, Gerald I. Shulman, Sheene Kim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(50)
Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α has been shown to play critical roles in regulating mitochondria biogenesis, respiration, and muscle oxidative phenotype. Furthermore, reductions in the expression of PGC-1α in musc
Autor:
David B Savage, Lanmin Zhai, Balasubramanian Ravikumar, Cheol Soo Choi, Johanna E Snaar, Amanda C McGuire, Sung-Eun Wou, Gemma Medina-Gomez, Sheene Kim, Cheryl B Bock, Dyann M Segvich, Bhavana Solanky, Dinesh Deelchand, Antonio Vidal-Puig, Nicholas J Wareham, Gerald I Shulman, Fredrik Karpe, Roy Taylor, Bartholomew A Pederson, Peter J Roach, Stephen O'Rahilly, Anna A DePaoli-Roach
Publikováno v:
PLoS Medicine
Autor:
Josep A, Villena, Cheol Soo, Choi, Yuhui, Wang, Sheene, Kim, Yu-Jin, Hwang, Young-Bum, Kim, Gary, Cline, Gerald I, Shulman, Hei Sook, Sul
Publikováno v:
Diabetes
OBJECTIVE—White adipose tissue is a critical regulator of whole-body glucose metabolism. Preadipocyte factor-1 (Pref-1) is a secreted protein that inhibits adipocyte differentiation, both in vitro and in vivo. In this study, we have investigated th