Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Sheena Pinto"'
Autor:
Montserrat Arnan, Pau Montesinos, Stéphane de Botton, Christian Recher, Lydia Wunderle, Michael Emig, Andreas Harstrick, Kerstin Pietzko, Sheena Pinto, Paulien Ravenstijn, Naval Daver
Publikováno v:
HemaSphere, Vol 7, p e2404792 (2023)
Externí odkaz:
https://doaj.org/article/b4d7a74d16094c5d9e7ece66f935eeac
Autor:
Jason A. Carter, Léonie Strömich, Matthew Peacey, Sarah R. Chapin, Lars Velten, Lars M. Steinmetz, Benedikt Brors, Sheena Pinto, Hannah V. Meyer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The thymus generates all T cells, including those that underly autoimmune diseases. Here, using deep sequencing, the authors profile human medullary thymic epithelial cells and establish a web portal to query their transcriptome, which may serve as a
Externí odkaz:
https://doaj.org/article/cd8d5709b0484a3e9ece600be3ca2e46
Autor:
Uwe Reusch, Joachim Koch, Sheena Pinto, Susanne Wingert, Jens Pahl, Armin Beez, Sabrina Purr, Arndt Schottelius
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6e5e4f7765b34750811e4f80882b6f79
Autor:
Joachim Koch, Sheena Pinto, Susanne Wingert, Jens Pahl, Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Björn Önfelt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adf
Autor:
Chiara Zambarda, Karolin Guldevall, Damien Toullec, Susanne Wingert, Christian Breunig, Sheena Pinto, Jacopo Fontana, Joachim Koch, Björn Önfelt
Publikováno v:
Cancer Research. 83:2950-2950
Antibody-Dependent Cellular Cytotoxicity (ADCC) is a powerful mechanism of Natural Killer (NK) cells to kill antibody-opsonized target cells. However, ADCC mediated by conventional antibodies has its limitations in killing of tumor cells commonly bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5c967aa78638a79869ea249df06bc03
https://doi.org/10.1158/1538-7445.am2023-2950
https://doi.org/10.1158/1538-7445.am2023-2950
Publikováno v:
Trends in immunology. 43(11)
Bi-, tri- and multispecific antibodies have enabled the development of targeted cancer immunotherapies redirecting immune effector cells to eliminate malignantly transformed cells. These antibodies allow for simultaneous binding of surface antigens o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478a351b1790934169523c2bead1b29c
https://pubmed.ncbi.nlm.nih.gov/36306739
https://pubmed.ncbi.nlm.nih.gov/36306739
Autor:
Chiara Zambarda, Karolin Guldevall, Christian Breunig, Damien Toullec, Jacopo Fontana, Sheena Pinto, Jens Pahl, Susanne Wingert, Joachim Koch, Björn Önfelt
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundThe use of bispecific natural killer (NK) cell engagers has emerged as a successful strategy for immune cell activation and killing of tumor cells through antibody-dependent cellular cytotoxicity (ADCC). Among these, tetravalent, bispecific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b100f0a38751dbd8cb307946ee8d85
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adf
https://doaj.org/article/dde28aa9a42d4f86ae8c60c460702adf
Autor:
Maki Nakayama, Maikel Luis Colli, Yann Verdier, Noemi Brusco, Lut Overbergh, Mark J. Mamula, Aïsha Callebaut, Joëlle Vinh, Guido Sebastiani, Georgia Afonso, Laura Nigi, Matthieu Giraud, Barbara Brandao, Zhicheng Zhou, Sylvaine You, Alexia Carré, Mijke Buitinga, Sheena Pinto, Marie Eliane Azoury, Decio L. Eizirik, Francesco Dotta, Chantal Mathieu, Søren Buus, Roberto Mallone, Fatoumata Samassa, Ana Ines Lalanne, Magali Irla
Publikováno v:
Diabetes
Diabetes, American Diabetes Association, 2021, pp.db210259. ⟨10.2337/db21-0259⟩
Diabetes, American Diabetes Association, 2021, pp.db210259. ⟨10.2337/db21-0259⟩
In type 1 diabetes, autoimmune β-cell destruction may be favored by neo-antigens harboring post-translational modifications such as citrullination. We studied the recognition of native and citrullinated glucose-regulated protein (GRP)78 peptides by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a38375b241b82cebe35b607398e6eea
https://doi.org/10.2337/figshare.16654669
https://doi.org/10.2337/figshare.16654669
Autor:
Marie Eliane, Azoury, Fatoumata, Samassa, Mijke, Buitinga, Laura, Nigi, Noemi, Brusco, Aïsha, Callebaut, Matthieu, Giraud, Magali, Irla, Ana Ines, Lalanne, Alexia, Carré, Georgia, Afonso, Zhicheng, Zhou, Barbara, Brandao, Maikel L, Colli, Guido, Sebastiani, Francesco, Dotta, Maki, Nakayama, Decio L, Eizirik, Sylvaine, You, Sheena, Pinto, Mark J, Mamula, Yann, Verdier, Joelle, Vinh, Soren, Buus, Chantal, Mathieu, Lut, Overbergh, Roberto, Mallone
Publikováno v:
Diabetes
In type 1 diabetes, autoimmune β-cell destruction may be favored by neoantigens harboring posttranslational modifications (PTMs) such as citrullination. We studied the recognition of native and citrullinated glucose-regulated protein (GRP)78 peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26bfd4c20eb62801dd9d13593f3b396
https://pubmed.ncbi.nlm.nih.gov/34561224
https://pubmed.ncbi.nlm.nih.gov/34561224
Autor:
Gabriele Hintzen, Erich Rajkovic, Uwe Reusch, Jens Pahl, Arndt Schottelius, Torsten Haneke, Christian Breunig, Wolfgang Fischer, Andreas Harstrick, Sheena Pinto, Joachim Koch, Cassandra Choe-Juliak
Publikováno v:
Cancer Research. 81:1881-1881
AFM24 engages CD16A (FcγRIIIa) on NK cells and macrophages with much higher affinity than monoclonal antibodies (mAbs), triggering NK cell-mediated ADCC and macrophage-mediated ADCP. AFM24's mode of action is highly differentiated from current EGFR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::648b22f37267ea46b5922c3d8fa34cdb
https://doi.org/10.1158/1538-7445.am2021-1881
https://doi.org/10.1158/1538-7445.am2021-1881