Zobrazeno 1 - 10
of 1 427
pro vyhledávání: '"Sheena M"'
Autor:
Heike Chauvistré, Batool Shannan, Sheena M. Daignault-Mill, Robert J. Ju, Daniel Picard, Stefanie Egetemaier, Renáta Váraljai, Christine S. Gibhardt, Antonio Sechi, Farnusch Kaschani, Oliver Keminer, Samantha J. Stehbens, Qin Liu, Xiangfan Yin, Kirujan Jeyakumar, Felix C. E. Vogel, Clemens Krepler, Vito W. Rebecca, Linda Kubat, Smiths S. Lueong, Jan Forster, Susanne Horn, Marc Remke, Michael Ehrmann, Annette Paschen, Jürgen C. Becker, Iris Helfrich, Daniel Rauh, Markus Kaiser, Sheraz Gul, Meenhard Herlyn, Ivan Bogeski, José Neptuno Rodríguez-López, Nikolas K. Haass, Dirk Schadendorf, Alexander Roesch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Slow-cycling melanoma persister cells are characterised by a high, reversible expression of H3K4 demethylase KDM5B. Here, the authors use genetic and chemical methods to enforce a permanent high expression of KDM5B and show that these cells transit t
Externí odkaz:
https://doaj.org/article/37bb3c7c6ed14e8aa7ac035cb7135585
Autor:
Krishnakumar Rajamani, MBBS, MD, Richard G. Moore, MD, Sheena M. Stanard, MD, Olga Astapova, MD, PhD
Publikováno v:
AACE Clinical Case Reports, Vol 8, Iss 3, Pp 135-138 (2022)
Background/Objective: Epithelial cell ovarian carcinomas rarely secrete steroid hormones, while sex cord and stromal cell ovarian carcinomas often do so. The objective of this report is to describe a patient with endometrioid ovarian carcinoma, an ep
Externí odkaz:
https://doaj.org/article/878f96d13f964a389bda8cb998c9b4dd
Autor:
Patricia M. Kearney, Sheena M. McHugh, Seán R. Millar, Ivan J. Perry, Katarzyna A. Gajewska, Janas M. Harrington, Lisa Delaney, Claire M. Buckley, Danko Stamenic
Publikováno v:
HRB Open Research, Vol 6 (2023)
Background: The Cork and Kerry Diabetes and Heart Disease Study was established to investigate the prevalence of diabetes and cardiovascular disease among middle-aged adults in Ireland. The Mitchelstown cohort was recruited from a single large primar
Externí odkaz:
https://doaj.org/article/b3f126ac619c40d685dd842f0fed4694
Publikováno v:
HRB Open Research, Vol 6 (2023)
Background: Recruitment challenges are a barrier to the conduct of trials in general practice, yet little is known about which recruitment strategies work best to recruit practices for randomised controlled trials (RCTs). We aimed to describe the typ
Externí odkaz:
https://doaj.org/article/45dea7093c2748dc947e8bb961603508
Autor:
Patricia M. Kearney, Lauren O Mahony, Emmy Racine, Gráinne Flynn, Fiona Riordan, Sheena M. McHugh
Publikováno v:
HRB Open Research, Vol 5 (2023)
Background: UK Medical Research Council guidelines recommend end-user involvement in intervention development. There is limited evidence on the contributions of different end-users to this process. The aim of this Study Within A Trial (SWAT) was to i
Externí odkaz:
https://doaj.org/article/4ae878a9fe1f46ce8f2995d85001a753
Autor:
Sean Dinneen, Lauren O'Mahony, Maire O'Donnell, Lorna Hurley, Cormac Sheehan, Fiona Riordan, Sheena M. McHugh, Katie Murphy
Publikováno v:
HRB Open Research, Vol 6 (2023)
Background: While models of integrated care for people with chronic conditions have demonstrated promising results, there are still knowledge gaps about how these models are implemented in different contexts and which strategies may best support impl
Externí odkaz:
https://doaj.org/article/72bd51966aa1471d9c8796ea92da0f19
Autor:
Geoff Curran, Sheena M McHugh, Byron J Powell, Cara C Lewis, Claire Kerins, Justin Presseau, Fiona Riordan, Luke Wolfenden
Publikováno v:
HRB Open Research, Vol 6 (2023)
Although there are effective evidence-based interventions (EBIs) to prevent, treat and coordinate care for chronic conditions they may not be adopted widely and when adopted, implementation challenges can limit their impact. Implementation strategies
Externí odkaz:
https://doaj.org/article/dfbf44765cda46a8bbf5b8910ac06f56
Autor:
Bianca Albers, Sheena M. McHugh, Nickola Pallin, Lauren Clack, Claire Kerins, Eimear Morrissey, Geoffrey M. Curran, Justin Presseau, Byron J. Powell, Cara C. Lewis, Fiona Riordan, Luke Wolfenden
Publikováno v:
HRB Open Research, Vol 5 (2022)
Background: Tailoring strategies to target the salient barriers to and enablers of implementation is considered a critical step in supporting successful delivery of evidence based interventions in healthcare. Theory, evidence, and stakeholder engagem
Externí odkaz:
https://doaj.org/article/6742e25455db4aa38378800a02357556
Autor:
Sheena M. Feist, Richard F. Lance
Publikováno v:
NeoBiota, Vol 66, Iss , Pp 117-159 (2021)
Sensitive methods, capable of rapidly and accurately detecting aquatic invasive species, are in demand. Molecular-based approaches, such as environmental DNA (eDNA) surveys, satisfy these requirements and have grown in popularity. As such, eDNA surve
Externí odkaz:
https://doaj.org/article/8be37e74f19940dab2a68a045eed5190
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Findings from gut microbiome studies are strongly influenced by both experimental and analytical factors that can unintentionally bias their interpretation. Environment is also critical. Both co-housing and maternal effects are expected to a
Externí odkaz:
https://doaj.org/article/dd2e2f3314e44cd681b20f0ea2334bf2