Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sheela R Damle"'
Autor:
Sheela R. Damle, Agata K. Krzyzanowska, Maximilian K. Korsun, Kyle W. Morse, Susannah Gilbert, Han Jo Kim, Oheneba Boachie-Adjei, Bernard A. Rawlins, Marjolein C. H. van der Meulen, Matthew B. Greenblatt, Chisa Hidaka, Matthew E. Cunningham
Publikováno v:
Cells, Vol 12, Iss 20, p 2488 (2023)
Bone morphogenetic protein (BMP) gene delivery to Lewis rat lumbar intervertebral discs (IVDs) drives bone formation anterior and external to the IVD, suggesting the IVD is inhospitable to osteogenesis. This study was designed to determine if IVD des
Externí odkaz:
https://doaj.org/article/d070ea3a8d62465ea1611f79d34193e0
Autor:
Andrea J. Luker, Laura J. Graham, Timothy M. Smith, Carmen Camarena, Matt P. Zellner, Jamie-Jean S. Gilmer, Sheela R. Damle, Daniel H. Conrad, Harry D. Bear, Rebecca K. Martin
Publikováno v:
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive ef
Externí odkaz:
https://doaj.org/article/8705275c0da24e8995eee5018ccbc1c7
Autor:
Rebecca K. Martin, Sheela R. Damle, Yolander A. Valentine, Matthew P. Zellner, Briana N. James, Joseph C. Lownik, Andrea J. Luker, Elijah H. Davis, Martha M. DeMeules, Laura M. Khandjian, Fred D. Finkelman, Joseph F. Urban, Jr., Daniel H. Conrad
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1824-1834 (2018)
Summary: Helminth infection is known for generating large amounts of poly-specific IgE. Here we demonstrate that innate-like B1 cells are responsible for this IgE production during infection with the nematode parasites Nippostrongylus brasiliensis an
Externí odkaz:
https://doaj.org/article/f4577ef0704b41a9a257d4dd0468027d
Autor:
Tony Chen, Miguel Otero, Matthew E. Cunningham, Sheela R. Damle, Robert J Frawley, Agata Krzyzanowska
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Spontaneous mineralization of the nucleus pulposus (NP) has been observed in cases of intervertebral disc degeneration (IDD). Inflammatory cytokines have been implicated in mineralization of multiple tissues through their modulation of expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61204c00598a6139051a4ebfe6721a4e
http://europepmc.org/articles/PMC8050288
http://europepmc.org/articles/PMC8050288
Autor:
Joseph C. Lownik, Lauren Folgosa Cooley, Riham El Sayed, Andrea J. Luker, Costantino Pitzalis, Rebecca K. Martin, Mohey Eldin M. El Shikh, Andreas Hutloff, Daniel H. Conrad, Sheela R. Damle
Publikováno v:
The Journal of Immunology. 199:2305-2315
The proper regulation of ICOS and ICOS ligand (ICOSL) has been shown to be essential for maintaining proper immune homeostasis. Loss of either protein results in defective humoral immunity, and overexpression of ICOS results in aberrant Ab production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711d1ec0ea8193b4518bc33ea0ff8e75
https://doi.org/10.4049/jimmunol.1700833
https://doi.org/10.4049/jimmunol.1700833
Autor:
Allen Smith, Daniel H. Conrad, Sheela R. Damle, Chelsea L. Cockburn, Joseph C. Lownik, Jason A. Carlyon, Rebecca K. Martin
Publikováno v:
Allergy. 73:125-136
Background Allergy and allergic asthma are significant health burdens in developed countries and are increasing in prevalence. Dendritic cells (DCs) initiate immune responses to common aeroallergens, and ADAM10 has been demonstrated to be important f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7ea3f9608a40c7e941fb39979dae5f
https://doi.org/10.1111/all.13261
https://doi.org/10.1111/all.13261
Autor:
Andrea J Luker, Laura J Graham, Matthew P Zellner, Jamie-Jean S Gilmer, Sheela R Damle, Daniel H Conrad, Rebecca K Martin, Harry D Bear
Background: Myeloid derived suppressor cells (MDSC) represent a significant hurdle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::535655981f3d0a2a6ca48d1ddc2f2a90
https://doi.org/10.21203/rs.2.15818/v1
https://doi.org/10.21203/rs.2.15818/v1
Autor:
Andrea J. Luker, Daniel H. Conrad, Jamie-Jean S. Gilmer, Harry D. Bear, Rebecca K. Martin, Matt P. Zellner, Timothy M. Smith, Laura Graham, Carmen Camarena, Sheela R. Damle
Publikováno v:
BMC Immunology
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Immunology, Vol 21, Iss 1, Pp 1-15 (2020)
Background Myeloid derived suppressor cells (MDSCs) present a significant obstacle to cancer immunotherapy because they dampen anti-tumor cytotoxic T cell responses. Previous groups, including our own, have reported on the myelo-depletive effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c479c83e1b42c2bc4eede0000911fb
https://pubmed.ncbi.nlm.nih.gov/32106810
https://pubmed.ncbi.nlm.nih.gov/32106810
Publikováno v:
Mucosal immunology
Infections with helminth parasites are endemic in the developing world and are a target for intervention with new therapies. Macrophage migration inhibitory factor (MIF) is a cytokine with pleiotropic effects in inflammation and immune responses. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61864e56a5584c7bf7ab8e246312ddf
http://europepmc.org/articles/PMC5053838
http://europepmc.org/articles/PMC5053838
Autor:
Hannah B. Zellner, Rebecca K. Martin, Harry D. Bear, Sheela R. Damle, Lauren Folgosa, John J. Ryan, Sheinei J. Saleem, Giang-Kim T. Nguyen, Daniel H. Conrad, Anne-Marie Irani
Publikováno v:
Journal of Leukocyte Biology. 96:151-159
It has been shown recently that MCs are required for differential regulation of the immune response by granulocytic versus monocytic MDSCs. Granulocytic MDSCs promoted parasite clearance, whereas monocytic MDSCs enhanced tumor progression; both activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe42607d8a4e6330c3e9f1b08d42fa4c
https://doi.org/10.1189/jlb.5a1213-644r
https://doi.org/10.1189/jlb.5a1213-644r