Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sheela Onnockx"'
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1448 (2023)
Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the assessment of subject safety, quality and efficacy aspects of medicinal products for human use, genetically
Externí odkaz:
https://doaj.org/article/ff6f92e4554e409da5c9258d6bfe2d44
Autor:
Anna Ardévol, Gerard Pujadas, Lluís Arola, Mayte Blay, M. Josepa Salvadó, Gemma Montagut, Isabelle Pirson, Montserrat Vaqué, Sheela Onnockx, Montserrat Pinent, Cinta Bladé, Juan Fernández-Larrea
Publikováno v:
The Journal of Nutritional Biochemistry. 21:476-481
Procyanidins are bioactive flavonoid compounds from fruits and vegetables that possess insulinomimetic properties, decreasing hyperglycaemia in streptozotocin-diabetic rats and stimulating glucose uptake in insulin-sensitive cell lines. Here we show
Autor:
Christophe Erneux, Marianne Blockmans, Jean-Marie Vanderwinden, Sheela Onnockx, Julie De Schutter, Christine Jacobs, Isabelle Pirson, Jingwei Xie
Publikováno v:
Journal of Cellular Physiology. 214:260-272
SHIP2 (SH2-containing inositol polyphosphate 5-phosphatase 2) is a phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P(3)) 5-phosphatase containing various motifs susceptible to mediate protein-protein interaction. In cell models, SHIP2 negati
Publikováno v:
FEBS Letters. 565:70-74
SH2 domain containing inositol polyphosphate 5-phosphatase (SHIP2) dephosphorylates phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) into phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). SHIP2 knock-out mice demonstrated that SHIP2 ac
Publikováno v:
Experimental cell research. 315(15)
Upon insulin stimulation, the adaptor protein APS is recruited to the insulin receptor and tyrosine phosphorylated. APS initiates the insulin-induced TC10 cascade which participates to GLUT4 translocation to the plasma membrane. Nevertheless, the mol
Autor:
Isabelle Pirson, Christophe Erneux, Jingwei Xie, Sheela Onnockx, Isabelle Vandenbroere, Chantal Degraef
Publikováno v:
Cellular signalling. 20(8)
SHIP2 (SH2-containing inositol polyphosphate 5-phosphatase 2) is an ubiquitously expressed phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P(3)) 5-phosphatase which contains various motifs susceptible to mediate protein-protein interaction.