Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sheeja, Rajasingh"'
Autor:
Zsuzsa Akos, Dona Greta Isai, Sheeja Rajasingh, Edina Kosa, Saba Ghazvini, Prajnaparamita Dhar, Andras Czirok
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The material properties of tissues and their mechanical state is an important factor in development, disease, regenerative medicine and tissue engineering. Here we describe a microrheological measurement technique utilizing aggregates of microinjecte
Externí odkaz:
https://doaj.org/article/9f61fd76afeb4cc4a70401b0896757f5
Autor:
Jayavardini Vasanthan, Narasimman Gurusamy, Sheeja Rajasingh, Vinoth Sigamani, Shivaani Kirankumar, Edwin L. Thomas, Johnson Rajasingh
Publikováno v:
Cells, Vol 10, Iss 1, p 54 (2020)
Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a regenerative microenvironment that has an excellent potential for tissue regenerati
Externí odkaz:
https://doaj.org/article/bd84b19ef6dc46fc86db29771467ae52
Publikováno v:
Current Genomics. 22:526-540
Aims: Perform in-silico analysis of human SOS1 mutations to elucidate their pathogenic role in Noonan syndrome (NS). Background: NS is an autosomal dominant genetic disorder caused by single nucleotide mutation in PTPN11, SOS1, RAF1, and KRAS genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d156fe50094445e80c70b279e79160a0
https://doi.org/10.2174/1389202922666211130144221
https://doi.org/10.2174/1389202922666211130144221
Autor:
Selene G Perales, Johnson Rajasingh, Jayavardini Vasanthan, Narasimman Gurusamy, Vinoth Sigamani, Sheeja Rajasingh, Shivaani Kirankumar
Publikováno v:
Exp Biol Med (Maywood)
The process of bone repair has always been a natural mystery. Although bones do repair themselves, supplemental treatment is required for the initiation of the self-regeneration process. Predominantly, surgical procedures are employed for bone regene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729d9eb7d454a5e21b46705ea511a260
https://doi.org/10.1177/15353702211052927
https://doi.org/10.1177/15353702211052927
Publikováno v:
Circulation Research. 131
Background: Current stem cells therapy for ischemic cardiomyopathy is effective only about 2-4% in improving cardiac function. In search of novel therapy, we have developed a safe mRNA-based reprogramming of non-invasively derived human urinary epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44911eddcccb66f459c87727b57d555e
https://doi.org/10.1161/res.131.suppl_1.p1038
https://doi.org/10.1161/res.131.suppl_1.p1038
Publikováno v:
Circulation Research. 131
Background: Hutchinson-Gilford progeria (HGP) is a rare genetic disorder in which children age rapidly. They suffer from atherosclerosis, cardiovascular diseases, and strokes. The LMNA variant c.1824C>T accounts for ~90% of HGP cases. This variant ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3086fc430feb0cd665170f959dba7305
https://doi.org/10.1161/res.131.suppl_1.p2111
https://doi.org/10.1161/res.131.suppl_1.p2111
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad1d05cc108b9211ca97cc0b8b0024fc
https://doi.org/10.1096/fasebj.2022.36.s1.r2171
https://doi.org/10.1096/fasebj.2022.36.s1.r2171
Autor:
Vinoth Sigamani, Shivaani Kirankumar, Jayavardini Vasanthan, Johnson Rajasingh, Sheeja Rajasingh, Edwin L. Thomas, Narasimman Gurusamy
Publikováno v:
Cells, Vol 10, Iss 54, p 54 (2021)
Cells
Cells
Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a regenerative microenvironment that has an excellent potential for tissue regenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5d5762beee2ca2a1b8e41e80c6e4a2
https://www.mdpi.com/2073-4409/10/1/54
https://www.mdpi.com/2073-4409/10/1/54
Publikováno v:
Circulation. 144
Introduction: Mesenchymal stem cells (MSC)-derived exosomes containing small non-coding RNAs (sncRNAs) showed protection of the myocardium from injury, infection, and disease. Recently, we have generated a safe and non-viral method of generating indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ae57ccd703f508e3926d969380b5eb
https://doi.org/10.1161/circ.144.suppl_1.12545
https://doi.org/10.1161/circ.144.suppl_1.12545
Publikováno v:
Circulation Research. 129
Background: Noonan syndrome (NS), a dominant autosomal genetic disorder that prevents normal development, and exhibits cardiac defects, which is estimated to appear in 50% to 90% of patients. Son of sevenless homolog 1 (SOS1) gene mutation has been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb8e1aaa213930982d130ad9a814749e
https://doi.org/10.1161/res.129.suppl_1.p470
https://doi.org/10.1161/res.129.suppl_1.p470