Septo-dentate gyrus cholinergic circuits modulate function and morphogenesis of adult neural stem cells through granule cell intermediaries.

Autor: Chen ZK; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Quintanilla L; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Su Y; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104., Sheehy RN; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Pharmacology Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Simon JM; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Carolina Institute for Developmental Disabilities, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Luo YJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Li YD; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Chen Z; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Asrican B; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Tart DS; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Farmer WT; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Ming GL; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Song H; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Song J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Oct; Vol. 121 (40), pp. e2405117121. Date of Electronic Publication: 2024 Sep 23.

Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease.

Autor: Li YD; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Luo YJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Xie L; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Tart DS; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Sheehy RN; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Pharmacology Curriculum, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Zhang L; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Coleman LG Jr; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Chen X; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Song J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: juansong@email.unc.edu.

Publikováno v: Cell stem cell [Cell Stem Cell] 2023 Apr 06; Vol. 30 (4), pp. 415-432.e6.

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.

Autor: Dorrier CE; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA., Aran D; Technion - Israel Institute of Technology, Haifa, Israel., Haenelt EA; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA., Sheehy RN; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA., Hoi KK; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Pintarić L; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA., Chen Y; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Lizama CO; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, USA., Cautivo KM; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA., Weiner GA; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA., Popko B; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Fancy SPJ; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Arnold TD; Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. thomas.arnold@ucsf.edu., Daneman R; Departments of Pharmacology and Neurosciences, University of California, San Diego, La Jolla, CA, USA. rdaneman@ucsd.edu.

Publikováno v: Nature neuroscience [Nat Neurosci] 2021 Feb; Vol. 24 (2), pp. 234-244. Date of Electronic Publication: 2021 Feb 01.