Pharmacologically enabling the degradation of NaV1.8 channels to reduce neuropathic pain.

Autor: Martin MK; Program for Neuroscience, University at Buffalo-The State University of New York, Buffalo, NY, United States., Rodriguez R; Pharmacology and Toxicology, University at Buffalo-The State University of New York, Buffalo, NY, United States. Dr. Powell is now with the Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, United States., Guerrero G; Pharmacology and Toxicology, University at Buffalo-The State University of New York, Buffalo, NY, United States. Dr. Powell is now with the Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, United States., Sheehan GD; Program for Neuroscience, University at Buffalo-The State University of New York, Buffalo, NY, United States., Powell R; Pharmacology and Toxicology, University at Buffalo-The State University of New York, Buffalo, NY, United States. Dr. Powell is now with the Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, United States., Klein AH; Program for Neuroscience, University at Buffalo-The State University of New York, Buffalo, NY, United States.; Pharmacology and Toxicology, University at Buffalo-The State University of New York, Buffalo, NY, United States. Dr. Powell is now with the Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, United States.; Department of Pharmacy Practice and Pharmaceutical Sciences, University of Minnesota, Duluth, MN, United States., Bhattacharjee A; Program for Neuroscience, University at Buffalo-The State University of New York, Buffalo, NY, United States.; Pharmacology and Toxicology, University at Buffalo-The State University of New York, Buffalo, NY, United States. Dr. Powell is now with the Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, United States.

Publikováno v: Pain [Pain] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08.

Thermal hyperalgesia and dynamic weight bearing share similar recovery dynamics in a sciatic nerve entrapment injury model.

Autor: Sheehan GD; Program in Neuroscience, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA., Martin MK; Program in Neuroscience, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA., Young VA; Program in Neuroscience, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA., Powell R; Department of Pharmacology and Toxicology, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA., Bhattacharjee A; Program in Neuroscience, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA.; Department of Pharmacology and Toxicology, University at Buffalo, The State University of New York, Buffalo, NY 14203, USA.

Publikováno v: Neurobiology of pain (Cambridge, Mass.) [Neurobiol Pain] 2021 Dec 06; Vol. 10, pp. 100079. Date of Electronic Publication: 2021 Dec 06 (Print Publication: 2021).

Pain's puzzle pieces: MAGI-1, NaV1.8, degradation, analgesia.

Autor: Gomez K; Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL, United States.; Pain and Addiction Therapeutics (PATH) Collaboratory, College of Medicine, University of Florida, Gainesville, FL, United States., Calderon-Rivera A; Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL, United States.; Pain and Addiction Therapeutics (PATH) Collaboratory, College of Medicine, University of Florida, Gainesville, FL, United States., Khanna R; Department of Pharmacology and Therapeutics, College of Medicine, University of Florida, Gainesville, FL, United States.; Pain and Addiction Therapeutics (PATH) Collaboratory, College of Medicine, University of Florida, Gainesville, FL, United States.

Publikováno v: Pain [Pain] 2024 Oct 30. Date of Electronic Publication: 2024 Oct 30.

A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy.

Autor: Gururaj S; Pharmacology and Toxicology, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA., Palmer EE; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia; Genetics of Learning Disability Service, Waratah, NSW 2298, Australia., Sheehan GD; Pharmacology and Toxicology, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA., Kandula T; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia., Macintosh R; Sydney Children's Hospital, Randwick, NSW 2031, Australia., Ying K; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Morris P; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Tao J; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Dias KR; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Zhu Y; Genetics of Learning Disability Service, Waratah, NSW 2298, Australia; SEALS Pathology, Randwick, NSW 2031, Australia., Dinger ME; University of New South Wales, Sydney, NSW 2031, Australia; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Cowley MJ; University of New South Wales, Sydney, NSW 2031, Australia; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, NSW 2298, Australia., Kirk EP; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia; SEALS Pathology, Randwick, NSW 2031, Australia., Roscioli T; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia; SEALS Pathology, Randwick, NSW 2031, Australia., Sachdev R; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia., Duffey ME; Physiology and Biophysics, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA., Bye A; Sydney Children's Hospital, Randwick, NSW 2031, Australia; University of New South Wales, Sydney, NSW 2031, Australia., Bhattacharjee A; Pharmacology and Toxicology, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA; Program for Neuroscience, University at Buffalo - The State University of New York, Buffalo, NY 14214, USA. Electronic address: ab68@buffalo.edu.

Publikováno v: Cell reports [Cell Rep] 2017 Oct 24; Vol. 21 (4), pp. 926-933.

An improved conflict avoidance assay reveals modality-specific differences in pain hypersensitivity across sexes.

Autor: Ferland, Samuel, Feng Wang, De Koninck, Yves, Ferrini, Francesco

Publikováno v: PAIN; Jun2024, Vol. 165 Issue 6, p1304-1316, 13p