Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Sheau-chiann Chen"'
Autor:
Rafael Paez, Robert J. Lentz, Cristina Salmon, Justin K. Siemann, See-Wei Low, Jonathan D. Casey, Heidi Chen, Sheau-Chiann Chen, Sameer Avasarala, Samira Shojaee, Otis B. Rickman, Christopher J. Lindsell, Cheryl L. Gatto, Todd W. Rice, Fabien Maldonado, for the Vanderbilt Learning Healthcare System Platform Investigators
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Robotic-assisted bronchoscopy has recently emerged as an alternative to electromagnetic navigational bronchoscopy for the evaluation of peripheral pulmonary lesions. While robotic-assisted bronchoscopy is proposed to have several
Externí odkaz:
https://doaj.org/article/0da1e295278d4a62abaf5511ef3477ed
Autor:
Rafael Paez, Michael N. Kammer, Aneri Balar, Dhairya A. Lakhani, Michael Knight, Dianna Rowe, David Xiao, Brent E. Heideman, Sanja L. Antic, Heidi Chen, Sheau-Chiann Chen, Tobias Peikert, Kim L. Sandler, Bennett A. Landman, Stephen A. Deppen, Eric L. Grogan, Fabien Maldonado
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract A deep learning model (LCP CNN) for the stratification of indeterminate pulmonary nodules (IPNs) demonstrated better discrimination than commonly used clinical prediction models. However, the LCP CNN score is based on a single timepoint that
Externí odkaz:
https://doaj.org/article/7b78666c04264aa586a2c11b09157b75
Autor:
George J. Xu, Matthew A. Loberg, Jean-Nicolas Gallant, Quanhu Sheng, Sheau-Chiann Chen, Brian D. Lehmann, Sophia M. Shaddy, Megan L. Tigue, Courtney J. Phifer, Li Wang, Mario W. Saab-Chalhoub, Lauren M. Dehan, Qiang Wei, Rui Chen, Bingshan Li, Christine Y. Kim, Donna C. Ferguson, James L. Netterville, Sarah L. Rohde, Carmen C. Solórzano, Lindsay A. Bischoff, Naira Baregamian, Aaron C. Shaver, Mitra Mehrad, Kim A. Ely, Daniel W. Byrne, Thomas P. Stricker, Barbara A. Murphy, Jennifer H. Choe, Luciane T. Kagohara, Elizabeth M. Jaffee, Eric C. Huang, Fei Ye, Ethan Lee, Vivian L. Weiss
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100409- (2023)
Summary: Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet, thyroid cancer management is largely guided by staging and histology, with few molecular prognostic and treatment biomarkers. Here, we utilize a large c
Externí odkaz:
https://doaj.org/article/fc1b6ef5686b46cf86fe3857f3b602c5
Autor:
Michael N. Kammer, PhD, Hidetoshi Mori, PhD, Dianna J. Rowe, BS, Sheau-Chiann Chen, PhD, Georgii Vasiukov, PhD, Thomas Atwater, MD, Maria Fernanda Senosain, PhD, Sanja Antic, MD, Yong Zou, MS, Heidi Chen, PhD, Tobias Peikert, MD, Steve Deppen, PhD, Eric L. Grogan, MD, Pierre P. Massion, MD, Steve Dubinett, MD, Marc Lenburg, PhD, Alexander Borowsky, MD, Fabien Maldonado, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 9, Pp 100504- (2023)
Introduction: Lung cancer is the deadliest cancer in the United States and worldwide, and lung adenocarcinoma (LUAD) is the most prevalent histologic subtype in the United States. LUAD exhibits a wide range of aggressiveness and risk of recurrence, b
Externí odkaz:
https://doaj.org/article/965e0718212541d0a561efc2131ac3f6
Autor:
Jean-Nicolas Gallant, Vivian L. Weiss, Sheau-Chiann Chen, Jiancong Liang, Ryan H. Belcher, Fei Ye, Hernan Correa, Huiying Wang
Publikováno v:
Cancers, Vol 15, Iss 19, p 4902 (2023)
The association between Hashimoto’s thyroiditis (HT) and pediatric thyroid cancer is controversial. Most studies examining this connection have been based on adults, and larger studies in children are lacking. We performed a retrospective study of
Externí odkaz:
https://doaj.org/article/23b4482cba624e03a5f49394180267fd
Autor:
Hannah E. Lomzenski, Geoffrey M. Thiele, Michael J. Duryee, Sheau-Chiann Chen, Fei Ye, Daniel R. Anderson, Ted R. Mikuls, Michelle J. Ormseth
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Patients with rheumatoid arthritis (RA) have increased atherosclerosis; oxidative stress may be a contributor. Oxidative stress produces immunogenic malondialdehyde-acetaldehyde (MAA) protein adducts and anti-MAA antibodies are detectable in
Externí odkaz:
https://doaj.org/article/d574f9ba36ab47a2a9f75bf1ebfd611c
Autor:
Chi Yan, Sheau-Chiann Chen, Gregory D. Ayers, Caroline A. Nebhan, Joseph T. Roland, Vivian L. Weiss, Douglas B. Johnson, Ann Richmond
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract Acquired resistance to BRAF/MEK-targeted therapy occurs in the majority of melanoma patients that harbor BRAF mutated tumors, leading to relapse or progression and the underlying mechanism is unclear in many cases. Using multiplex immunohist
Externí odkaz:
https://doaj.org/article/e4ad515d7bef45609e1d3c63d929983a
Autor:
S.M. Jamshedur Rahman, Sheau-Chiann Chen, Yi-Ting Wang, Yuqian Gao, Athena A. Schepmoes, Thomas L. Fillmore, Tujin Shi, Heidi Chen, Karin D. Rodland, Pierre P. Massion, Eric L. Grogan, Tao Liu
Publikováno v:
Cancers, Vol 15, Iss 18, p 4504 (2023)
A major challenge in lung cancer prevention and cure hinges on identifying the at-risk population that ultimately develops lung cancer. Previously, we reported proteomic alterations in the cytologically normal bronchial epithelial cells collected fro
Externí odkaz:
https://doaj.org/article/aaf49d3ff7a1432592ca1b7648e17d66
Autor:
Chi Yan, Caroline A. Nebhan, Nabil Saleh, Rebecca Shattuck-Brandt, Sheau-Chiann Chen, Gregory D. Ayers, Vivian Weiss, Ann Richmond, Anna E. Vilgelm
Publikováno v:
Cancers, Vol 15, Iss 14, p 3695 (2023)
Current methodologies for developing PDX in humanized mice in preclinical trials with immune-based therapies are limited by GVHD. Here, we compared two approaches for establishing PDX tumors in humanized mice: (1) PDX are first established in immune-
Externí odkaz:
https://doaj.org/article/cd96e2e13b2c42d0a9a863761658c155
Autor:
Chi Yan, Nabil Saleh, Jinming Yang, Caroline A. Nebhan, Anna E. Vilgelm, E. Premkumar Reddy, Joseph T. Roland, Douglas B. Johnson, Sheau-Chiann Chen, Rebecca L. Shattuck-Brandt, Gregory D. Ayers, Ann Richmond
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Abstract Background While immune checkpoint blockade (ICB) is the current first-line treatment for metastatic melanoma, it is effective for ~ 52% of patients and has dangerous side effects. The objective here was to identify the feasibility and mecha
Externí odkaz:
https://doaj.org/article/82bb453360e248c5bc1c0f112efb95c9