Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shazia Irshad"'
Autor:
Shamir Montazid, Sheila Bandyopadhyay, Daniel W. Hart, Nan Gao, Brian Johnson, Sri G. Thrumurthy, Dustin J. Penn, Bettina Wernisch, Mukesh Bansal, Philipp M. Altrock, Fabian Rost, Patrycja Gazinska, Piotr Ziolkowski, Bu’Hussain Hayee, Yue Liu, Jiangmeng Han, Annamaria Tessitore, Jana Koth, Walter F. Bodmer, James E. East, Nigel C. Bennett, Ian Tomlinson, Shazia Irshad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The naked mole rat (NMR), Heterocephalus glaber, the longest-living rodent, provides a unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity and tissue function with increasing lifespan. Using cumulative BrdU
Externí odkaz:
https://doaj.org/article/be2026cd202c4604a72718d25fbf1ee3
Autor:
Shazia Irshad, Shamir Montazid, Daniel Hart, Sheila Bandyopadhyay, Brian Johnson, Sri Thrumurthy, Nan Gao, Mukesh Bansal, Philipp Altrock, Fabian Rost, Dustin Penn, Bettina Wernisch, Patrycja Gazinska, Piotr Ziółkowski, Bu'Hussain Hayee, Annamaria Tessitore, Walter Bodmer, James East, Nigel Bennett, Ian Tomlinson
The naked mole rat (NMR), Heterocephalus glaber, the longest-living rodent1, provides a unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity with increasing lifespan. Using cumulative BrdU labelling and a quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44c23da3b493211df4583495f654f06
https://doi.org/10.21203/rs.3.rs-2674841/v1
https://doi.org/10.21203/rs.3.rs-2674841/v1
Autor:
Joseph D. Fondell, Cory Abate-Shen, Michael M. Ittmann, Marina Chekmareva, Madesh Belakavadi, Wei Yu, Shazia Irshad, Feng Jin
PDF file - 529K, Fig. S1. MED1 antibody specificity. Fig. S2. Anti-phospho-MED1 antibody specificity. Fig. S3. Inhibition of ERK or AKT signaling decreases MED1 phosphorylation and expression in prostate cancer cells. Fig. S4. Phospho-MED1 binds to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524a8cfd63089d32200a22c453295e49
https://doi.org/10.1158/1541-7786.22510099.v1
https://doi.org/10.1158/1541-7786.22510099.v1
Autor:
Joseph D. Fondell, Cory Abate-Shen, Michael M. Ittmann, Marina Chekmareva, Madesh Belakavadi, Wei Yu, Shazia Irshad, Feng Jin
MED1 is a key coactivator of the androgen receptor (AR) and other signal-activated transcription factors. Whereas MED1 is overexpressed in prostate cancer cell lines and is thought to coactivate distinct target genes involved in cell-cycle progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fa49ad8ec0af6abc8be54dcbb220e7
https://doi.org/10.1158/1541-7786.c.6539506.v1
https://doi.org/10.1158/1541-7786.c.6539506.v1
Autor:
Ian Tomlinson, Shazia Irshad, Stefania Segditsas, Chiara Bardella, Tia Mirshahi, Sujata Biswas, Thomas Starkey, Connor Woolley, Lennard Y.W. Lee
Purpose:The molecular events that determine intestinal cell differentiation are poorly understood and it is unclear whether it is primarily a passive event or an active process. It is clinically important to gain a greater understanding of the proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5527632899eac34ae2404213d3c9974f
https://doi.org/10.1158/1078-0432.c.6529032
https://doi.org/10.1158/1078-0432.c.6529032
Autor:
Ian Tomlinson, Shazia Irshad, Stefania Segditsas, Chiara Bardella, Tia Mirshahi, Sujata Biswas, Thomas Starkey, Connor Woolley, Lennard Y.W. Lee
Supplementary Table 1. Differentially expressed genes from colonic crypt tops vs. bottoms of normal individuals (adjusted p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea0aeccbf160beddb08a6404a21b2a9
https://doi.org/10.1158/1078-0432.22475289.v1
https://doi.org/10.1158/1078-0432.22475289.v1
Autor:
Syed Far Abid Hossain, Kazi Mohiuddin, Faiza Tanaz Ahsan, Hasan Mahmud, Arslan Amzad, Shazia Irshad
Publikováno v:
Technology Application in Tourism Fairs, Festivals and Events in Asia ISBN: 9789811680694
China is a tourism-focused country with numerous historical attractions like the great wall and terracotta warriors. This chapter aims to explore the role of technology-based tourism development mechanisms in China with the help of tourism events, fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f00b2bbefcdfcb4882378861dca167
https://doi.org/10.1007/978-981-16-8070-0_16
https://doi.org/10.1007/978-981-16-8070-0_16
Autor:
Lennard Y W Lee, Shazia Irshad, Chiara Bardella, Sujata Biswas, Stefania Segditsas, Connor Woolley, Tia S Mirshahi, Thomas Starkey, Ian Tomlinson
Publikováno v:
Clinical Cancer Research. 25:629-640
Purpose: The molecular events that determine intestinal cell differentiation are poorly understood and it is unclear whether it is primarily a passive event or an active process. It is clinically important to gain a greater understanding of the proce
Publikováno v:
The primary care companion for CNS disorders. 22(4)
Autor:
Shazia, Irshad, Mukesh, Bansal, Paolo, Guarnieri, Hayley, Davis, Ayman, Al Haj Zen, Brygida, Baran, Claudia Maria Assunta, Pinna, Haseeb, Rahman, Sujata, Biswas, Chiara, Bardella, Rosemary, Jeffery, Lai Mun, Wang, James Edward, East, Ian, Tomlinson, Annabelle, Lewis, Simon John, Leedham
Publikováno v:
The Journal of pathology. 242(2)
The functional role of bone morphogenetic protein (BMP) signalling in colorectal cancer (CRC) is poorly defined, with contradictory results in cancer cell line models reflecting the inherent difficulties of assessing a signalling pathway that is cont