Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shayne C Barlow"'
Autor:
Stephanie L Samani, Shayne C Barlow, Lisa A Freeburg, Traci L Jones, Marlee Poole, Mark A Sarzynski, Michael R Zile, Tarek Shazly, Francis G Spinale
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0292243 (2024)
BackgroundStandardized exercise protocols have been shown to improve overall cardiovascular fitness, but direct effects on left ventricular (LV) function, particularly diastolic function and relation to post-transcriptional molecular pathways (microR
Externí odkaz:
https://doaj.org/article/f0f0cf33b3ec4f5286355ca0b5c3e294
Autor:
Heather Doviak, Amber Moore, William M. Torres, Michael R. Zile, Abigail C. Hoenes, Shayne C. Barlow, Lisa A. Freeburg, Tarek Shazly, Francis G. Spinale
Publikováno v:
JACC: Basic to Translational Science. 5:463-480
Summary This study assessed the regional changes in myocardial geometry, microstructure, mechanical behavior, and properties that occur in response to progressive left ventricular pressure overload (LVPO) in a large animal model. Using an index of lo
Autor:
Vimala Kaza, Asieh Naderi, Shayne C. Barlow, Hippokratis Kiaris, Elham Soltanmaohammadi, Ioulia Chatzistamou
Publikováno v:
eLife, Vol 10 (2021)
People’s social interactions could influence their risk of developing various diseases, including cancer, according to population-level studies. In particular, studies have identified a so-called widowhood effect where a person’s risk of disease
Autor:
Michael R. Zile, William M. Torres, Shayne C. Barlow, Francis G. Spinale, Heather Doviak, Julia Jacobs, Tarek Shazly
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 315:H958-H967
The aim of the present study was to serially track how myocardial infarction (MI) impacts regional myocardial strain and mechanical properties of the left ventricle (LV) in a large animal model. Post-MI remodeling has distinct regional effects throug
Autor:
Shayne C. Barlow, TaeWeon Lee, Heather Doviak, Ran Klein, Julia Jacobs, Robert A. deKemp, Kia N. Zellars, Albert J. Sinusas, Jennifer M. Renaud, Stephanie Thorn, Mitchel R. Stacy, Attila Feher, Aarif Y. Khakoo, Francis G. Spinale
Publikováno v:
Circulation: Cardiovascular Imaging. 12
Background: The induction of matrix metalloproteinases (MMPs) and reduction in tissue inhibitors of MMPs (TIMPs) plays a role in ischemia/reperfusion (I/R) injury post-myocardial infarction (MI) and subsequent left ventricular remodeling. We develope
Autor:
Stephanie L, Thorn, Shayne C, Barlow, Attila, Feher, Mitchel R, Stacy, Heather, Doviak, Julia, Jacobs, Kia, Zellars, Jennifer M, Renaud, Ran, Klein, Robert A, deKemp, Aarif Y, Khakoo, TaeWeon, Lee, Francis G, Spinale, Albert J, Sinusas
Publikováno v:
Circ Cardiovasc Imaging
BACKGROUND: The induction of matrix metalloproteinases (MMPs), and reduction in tissue inhibitors of MMPs (TIMPs) plays a role in ischemia/reperfusion (I/R) injury post myocardial infarction (MI) and subsequent left ventricular (LV) remodeling. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::685352f51ea018d646f9eb2c5d3d8023
https://europepmc.org/articles/PMC7250243/
https://europepmc.org/articles/PMC7250243/
Autor:
Heather Doviak, Abigail Hoenes, Aarif Y. Khakoo, Jason A. Burdick, Kia N. Zellars, Julia Jacobs, Lisa A. Freeburg, Francis G. Spinale, Shayne C. Barlow, Brendan P. Purcell, TaeWeon Lee, Paige E. Perreault
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 315(4)
Although improvements in timing and approach for early reperfusion with acute coronary syndromes have occurred, myocardial injury culminating in a myocardial infarction (MI) remains a common event. Although a multifactorial process, an imbalance betw
Autor:
Lisa A. Freeburg, Camila F. Villacreses, Stephen Smith, TaeWeon Lee, Aarif Y. Khakoo, Julia Jacobs, Heather Doviak, Shayne C. Barlow, Kia N. Zellars, Karen Moreau, Paige E Perreault, Francis G. Spinale
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 313(4)
Ischemia-reperfusion (IR) and myocardial infarction (MI) cause adverse left ventricular (LV) remodeling and heart failure and are facilitated by an imbalance in matrix metalloproteinase (MMP) activation and the endogenous tissue inhibitors of metallo
Autor:
Jeffrey R. Patton, Joshua E. Mangum, Anoop K. Sendamarai, Shayne C. Barlow, Melissa J. Puppa, Hart G.W. Lidov, Nathan Fischel-Ghodsian, Paul J. Schmidt, Diego Altomare, Johnathon Elkes, James A. Carson, Justin P. Hardee, Dean R. Campagna, Dennis K. Fix, Yelena Bykhovskaya, Mark D. Fleming
Publikováno v:
Scientific Reports
Mitochondrial myopathy with lactic acidosis and sideroblastic anemia (MLASA) is an oxidative phosphorylation disorder, with primary clinical manifestations of myopathic exercise intolerance and a macrocytic sideroblastic anemia. One cause of MLASA is