Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shayna Sandhaus"'
Autor:
Bokun Cheng, Thirunavukkarasu Annamalai, Shayna Sandhaus, Priyanka Bansod, Yuk-Ching Tse-Dinh
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120022 (2015)
Type IA topoisomerase activities are essential for resolving DNA topological barriers via an enzyme-mediated transient single strand DNA break. Accumulation of topoisomerase DNA cleavage product can lead to cell death or genomic rearrangement. Many a
Externí odkaz:
https://doaj.org/article/6944cadac5554f84ab898a9d26382760
Autor:
Shayna Sandhaus, Andrew G. Swick
Publikováno v:
Biofactors (Oxford, England)
BioFactors
BioFactors
Specialized proresolving mediators (SPMs) are endogenous lipid metabolites of long‐chain polyunsaturated fatty acids that are involved in promoting the resolution of inflammation. Many disease conditions characterized by excessive inflammation have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864e174fe3a8ae0c09bb956d93af5b5d
https://doi.org/10.1002/biof.1691
https://doi.org/10.1002/biof.1691
Autor:
Yuk-Ching Tse-Dinh, Courtney E. Stankavich, Sydney R. Foster, Jimmie L. Bullock, Jasmine S. Clark, Donald M. Cropek, Jessa Faye Arca, Shayna Sandhaus, Stephen J. Beebe, Raj K. Gurung, William L. Jarrett, Criszcele M. Tano, Michael J. Celestine, Alvin A. Holder, Floyd A. Beckford, Elizabeth A. Tonsel-White, Tekettay A. Ludvig
Publikováno v:
Journal of inorganic biochemistry. 203
In this study, 9-anthraldehyde-N(4)-methylthiosemicarbazone (MeATSC) 1 and [Co(phen)(2)(O(2)CO)]Cl·6H(2)O 2 (where phen = 1,10-phenanthroline) were synthesized. [Co(phen)(2)(O(2)CO)]Cl·6H(2)O 2 was used to produce anhydrous [Co(phen)(2)(H(2)O)(2)](
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0a8e48d9981fca08ac894929fb067d
https://pubmed.ncbi.nlm.nih.gov/31715377
https://pubmed.ncbi.nlm.nih.gov/31715377
Autor:
Patrice Cagle, Antonio González-Sarrías, Yuk-Ching Tse-Dinh, Ramaiyer Venkatraman, Ykeysha Wooten, Alexis Huddleston, Rosella Taylor, Tiffany Edwards, Alvin A. Holder, Shayna Sandhaus, Navindra P. Seeram, Stephen J. Beebe, Patrick M. Martin, Ralph T. Weber
Publikováno v:
Inorganic Chemistry Communications. 64:45-49
A novel complex, [Cu(acetylethTSC)Cl]Cl•0.25C2H5OH 1 (where acetylethTSC = (E)-N-ethyl-2-[1-(thiazol-2-yl)ethylidene]hydrazinecarbothioamide), was shown to have anti-proliferative activity against various colon and aggressive breast cancer cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e85c1e6f7d6d8567ac434cffa9a30d
https://doi.org/10.1016/j.inoche.2015.12.013
https://doi.org/10.1016/j.inoche.2015.12.013
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Topoisomerases are important targets for antibacterial and anticancer therapies. Bacterial topoisomerase I remains to be exploited for antibiotics that can be used in the clinic. Inhibitors of bacterial topoisomerase I may provide leads for novel ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e3cba22e1f9c8d637eec184730b17d
https://doi.org/10.1038/s41598-018-19944-4
https://doi.org/10.1038/s41598-018-19944-4
Autor:
Yuk-Ching Tse-Dinh, Charles J. Simmons, Li Feng, Shayna Sandhaus, Gagandeep Narula, Dianqing Sun, Lissa S. Tsutsumi, Xiaoqian Wu, Julian G. Hurdle, Marcus M. Maddox, David F. Bruhn, Richard E. Lee, Zahidul Alam, Robin B. Lee
Publikováno v:
Journal of Medicinal Chemistry
On the basis of recently reported abyssinone II and olympicin A, a series of chemically modified flavonoid phytochemicals were synthesized and evaluated against Mycobacterium tuberculosis and a panel of Gram-positive and -negative bacterial pathogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4db5e07550e7043455e95f863939b0f
https://doi.org/10.1021/jm500853v
https://doi.org/10.1021/jm500853v
Autor:
Thirunavukkarasu Annamalai, Sandra Geden, Richard A. Houghten, Carolina Rodrigues Felix, Yuk-Ching Tse-Dinh, Mandy Netherton, Shayna Sandhaus, Marc A. Giulianotti, Angelo Andres, Pamela K. Garcia, Kyle H. Rohde, Carlos Paz, Rashmi Gupta, Greg Welmaker, Gagandeep Narula
Publikováno v:
Antimicrobial agents and chemotherapy. 60(7)
Bacterial topoisomerase functions are required for regulation of DNA supercoiling and overcoming the DNA topological barriers that are encountered during many vital cellular processes. DNA gyrase and topoisomerase IV of the type IIA bacterial topoiso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18286262b83e51b2923a5cc40be22f7
https://pubmed.ncbi.nlm.nih.gov/27114277
https://pubmed.ncbi.nlm.nih.gov/27114277