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pro vyhledávání: '"Shaye B. Hagler"'
Autor:
Shaye B. Hagler, Juli R. Bagó, Morgan Goetz, Abigail G. Carey-Ewend, Hunter N. Bomba, Shawn Hingtgen
Publikováno v:
Tissue engineering. Part A. 27(13-14)
Engineered neural stem cells (NSCs) have recently emerged as a promising therapy. Acting as a tumor-homing drug-delivery system, NSCs migrate through brain tissue to seek out primary and invasive tumor foci. NSCs can deliver therapeutic agents, such
Autor:
Spencer M. Maingi, Andrew Buckley, Matthew G. Ewend, Simon Khagi, Juli R. Bagó, Shaye B. Hagler, Shawn Hingtgen, Vivien Lettry, C. Ryan Miller
Publikováno v:
Neuro Oncol
Induced neural stem-cells (iNSCs) represent a new opportunity in the emerging field of cellular immunotherapy. Patient-derived iNSCs modified to produce anti-tumoral compounds could lead to less rejection and safer outcomes than an off-the-shelf ther
Publikováno v:
Current Surgery Reports. 5
Emerging evidence has demonstrated that genetically engineered stem cells have unique tumor-homing capacity that allows them to deliver anticancer gene products directly into local and invasive glioblastoma foci. New clinical trials have been launche
Publikováno v:
Neuro-Oncology. 20:vi275-vi275
Tumor-homing neural stem cell (NSC) therapy is a promising new strategy that recently entered human patient testing for glioblastoma (GBM). The success of NSCs in the clinic will depend on their ability to overcome the heterogeneity and invasiveness