Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shawna M Hengel"'
Autor:
Kathryn E Marshall, Errol W Robinson, Shawna M Hengel, Ljiljana Paša-Tolić, Guritno Roesijadi
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33771 (2012)
Future materials are envisioned to include bio-assembled, hybrid, three-dimensional nanosystems that incorporate functional proteins. Diatoms are amenable to genetic modification for localization of recombinant proteins in the biosilica cell wall. Ho
Externí odkaz:
https://doaj.org/article/b7dbde94e7a1401c8eceebe7053b2d1a
Publikováno v:
Bioanalysis. 14:1443-1452
Tucatinib, a tyrosine kinase inhibitor of HER2, is approved in multiple regions for metastatic breast cancer and is being evaluated in metastatic colorectal and gastric cancers. During clinical development, quantification of tucatinib plasma concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80a7d766339de37244d7ea9e7174366
https://doi.org/10.4155/bio-2022-0199
https://doi.org/10.4155/bio-2022-0199
Autor:
Shawna M. Hengel, Joshua T. Aldrich, Katrina M. Waters, Ljiljana Pasa-Tolic, David L. Stenoien
Publikováno v:
Proteomes, Vol 2, Iss 3, Pp 382-398 (2014)
To assess responses to low-dose ionizing radiation (LD-IR) exposures potentially encountered during medical diagnostic procedures, nuclear accidents or terrorist acts, a quantitative proteomic approach was used to identify changes in protein abundanc
Externí odkaz:
https://doaj.org/article/5609de3ee6424f26a1a0400089e63d56
Autor:
Si Wu, Zhixin Tian, Heather S. Smallwood, Svetlana Rezinciuc, Shawna M. Hengel, Ljiljana Paša-Tolić
Publikováno v:
Viruses, Vol 12, Iss 1409, p 1409 (2020)
Viruses
Volume 12
Issue 12
Viruses
Volume 12
Issue 12
T cell function is determined by transcriptional networks that are regulated by epigenetic programming via posttranslational modifications (PTMs) to histone proteins and DNA. Bottom-up mass spectrometry (MS) can identify histone PTMs, whereas intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bed136520e4110380a68063661b666
https://www.mdpi.com/1999-4915/12/12/1409
https://www.mdpi.com/1999-4915/12/12/1409
T cell function is determined by transcriptional networks that are regulated by epigenetic programming via posttranslational modifications (PTMs) of histone proteins and DNA. Bottom-up mass spectrometry (MS) can identify histone PTMs, whereas intact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42a94e5f78e2f415e5151250f3addc57
Publikováno v:
Molecular Pharmacology. 86:665-674
Ritonavir is a human immunodeficiency virus (HIV) protease inhibitor and an inhibitor of cytochrome P450 3A4, the major human hepatic drug-metabolizing enzyme. Given the potent inhibition of CYP3A4 by ritonavir, subtherapeutic doses of ritonavir are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64a77825f4e7479e65956271e1d75ec
https://doi.org/10.1124/mol.114.094862
https://doi.org/10.1124/mol.114.094862
Publikováno v:
Journal of Proteome Research. 12:5830-5838
Post-translational modifications (PTMs) play an important role in various biological processes through changing protein structure and function. Some ultramodified proteins (like histones) have multiple PTMs forming PTM patterns that define the functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97726e3091eb42a017ce65095479cf50
https://doi.org/10.1021/pr400849y
https://doi.org/10.1021/pr400849y
Autor:
Amber Streifel, David R. Goodlett, Steve L. Moseley, Carleen M. Collins, Lisette H. Coye, Shawna M. Hengel, Laura M. Icenogle
Publikováno v:
Journal of Biological Chemistry. 287:21481-21491
The Gram-positive bacterial pathogen Streptococcus pyogenes produces a C3 family ADP-ribosyltransferase designated SpyA (S. pyogenes ADP-ribosyltransferase). Our laboratory has identified a number of eukaryotic protein targets for SpyA, prominent amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ab40f952d58d0e9bfc01138438583c
https://doi.org/10.1074/jbc.m112.370791
https://doi.org/10.1074/jbc.m112.370791
Autor:
Shawna M. Hengel, David R. Goodlett
Publikováno v:
International Journal of Mass Spectrometry. 312:114-121
The use of tandem mass spectrometry to identify and characterize sites of protein adenosine diphosphate (ADP) ribosylation will be reviewed. Specifically, we will focus on data acquisition schemes and fragmentation techniques that provide peptide seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12967ea38f5c43d91e61814919583b72
https://doi.org/10.1016/j.ijms.2011.06.003
https://doi.org/10.1016/j.ijms.2011.06.003
Autor:
Ted R. Hupp, Shawna M. Hengel, Larry Hayward, Euan Murray, Jean E O’Donoghue, David R. Goodlett, Alexandre Panchaud, Simon P. Langdon
Publikováno v:
Hengel, S M, Murray, E, Langdon, S, Hayward, L, O'Donoghue, J, Panchaud, A, Hupp, T & Goodlett, D R 2011, ' Data-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistance ', Journal Of Proteome Research, vol. 10, no. 10, pp. 4567-78 . https://doi.org/10.1021/pr2004117
A label-free quantitative variation of the recently developed data-independent shotgun proteomic method Precursor Acquisition Independent From Ion Count (PAcIFIC) was used to identify novel proteins implicated in cancer progression and resistance. Sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51439289e1ef9599c3e8d9c57e937c70
https://doi.org/10.1021/pr2004117
https://doi.org/10.1021/pr2004117