Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shawna L Organ"'
Autor:
Shawna L Organ, Josephine Hai, Nikolina Radulovich, Christopher B Marshall, Lisa Leung, Takehiko Sasazuki, Senji Shirasawa, Chang-Qi Zhu, Roya Navab, Mitsuhiko Ikura, Ming-Sound Tsao
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86103 (2014)
KRAS is mutated in ∼40% of colorectal cancer (CRC), and there are limited effective treatments for advanced KRAS mutant CRC. Therefore, it is crucial that downstream mediators of oncogenic KRAS continue to be studied. We identified p190RhoGAP as be
Externí odkaz:
https://doaj.org/article/6d72e1f7b48344a7af4bccae51d2c420
Autor:
Abdellah Allali-Hassani, Magdalena M. Szewczyk, Danton Ivanochko, Shawna L. Organ, Jabez Bok, Jessica Sook Yuin Ho, Florence P. H. Gay, Fengling Li, Levi Blazer, Mohammad S. Eram, Levon Halabelian, David Dilworth, Genna M. Luciani, Evelyne Lima-Fernandes, Qin Wu, Peter Loppnau, Nathan Palmer, S. Zakiah A. Talib, Peter J. Brown, Matthieu Schapira, Philipp Kaldis, Ronan C. O’Hagan, Ernesto Guccione, Dalia Barsyte-Lovejoy, Cheryl H. Arrowsmith, John M. Sanders, Solomon D. Kattar, D. Jonathan Bennett, Benjamin Nicholson, Masoud Vedadi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
PRDM9 is a PR domain containing histone methyl transferase which expression is normally restricted to the germline that has also been linked to a number of somatic cancers. Here the authors describe the identification of a small molecule that selecti
Externí odkaz:
https://doaj.org/article/38d967925aeb49498c5e1209a2983c26
Autor:
Angela Y. Hui, Jalna Meens, Colleen Schick, Shawna L. Organ, Eric Tremblay, Bruce E. Elliott, Shashi Uniyal, Erik Schaeffer, Bosco M.C. Chan, Hui Qiao
Publikováno v:
Journal of Cellular Biochemistry. 107:1168-1181
Cell-matrix adhesion has been shown to promote activation of the hepatocyte growth factor receptor, Met, in a ligand-independent manner. This process has been linked to transformation and tumorigenesis in a variety of cancer types. In the present rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd589683a1d72563ebb3e8d897ed3e3
https://doi.org/10.1002/jcb.22219
https://doi.org/10.1002/jcb.22219
Autor:
Jalna Meens, Victoria Hoskin, Jenna Pilon, Graham P. Côté, Bruce E. Elliott, Shawna L. Organ, Emilia Furmaniak-Kazmierczak
Publikováno v:
Cancer Research. 70:535A-535A
Over-expression and aberrant activation of the Met proto-oncogene frequently occurs in invasive breast cancer, and is linked with poor patient prognosis. We and others have shown that the tyrosine kinase Src mediates cell-adhesion dependent activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d9358bd2c9ea9e87b8a7b4f22c03203
https://doi.org/10.1158/1538-7445.am10-535a
https://doi.org/10.1158/1538-7445.am10-535a
Autor:
Shawna L. Organ, Jiefei Tong, Paul Taylor, Jonathan R. St-Germain, Roya Navab, Michael F. Moran, Ming-Sound Tsao
Publikováno v:
Journal of Proteome Research; Jul2011, Vol. 10 Issue 7, p3200-3211, 12p