Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Shawn Zheng Kai Tan"'
Autor:
Shawn Zheng Kai Tan, Huseyin Kir, Brian D. Aevermann, Tom Gillespie, Nomi Harris, Michael J. Hawrylycz, Nikolas L. Jorstad, Ed S. Lein, Nicolas Matentzoglu, Jeremy A. Miller, Tyler S. Mollenkopf, Christopher J. Mungall, Patrick L. Ray, Raymond E. A. Sanchez, Brian Staats, Jim Vermillion, Ambika Yadav, Yun Zhang, Richard H. Scheuermann, David Osumi-Sutherland
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Large-scale single-cell ‘omics profiling is being used to define a complete catalogue of brain cell types, something that traditional methods struggle with due to the diversity and complexity of the brain. But this poses a problem: How do
Externí odkaz:
https://doaj.org/article/4f10383326124ce5a17e01aae7951008
Autor:
Michael Hawrylycz, Maryann E Martone, Giorgio A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Patrick R Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H Scheuermann, Shawn Zheng Kai Tan, Carol L Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L Athey, Cody Baker, Katherine S Baker, Pamela M Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D'Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O Halchenko, Nomi L Harris, Brian R Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L Mathews, Chris Mezias, Michael I Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J Mungall, Joshua Orvis, Maja A Puchades, Lei Qu, Joseph P Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T J van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W Jim Zheng, Brian Zingg
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002133 (2023)
Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is also essential to manipulate cell typ
Externí odkaz:
https://doaj.org/article/5683e726eb424a3187544a44691a1d0f
Autor:
Wing Shan Yu, Li Guan, Shawn Zheng Kai Tan, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Valerie Chun Ling Lin, Lee Wei Lim
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 6, Pp 698-703 (2022)
Objective(s): The involvement of tetratricopeptide repeat domain 9A (TTC9A) in anxiety-like behaviors through estrogen action has been reported in female mice, this study further investigated its effects on social anxiety and aggressive behaviors.Mat
Externí odkaz:
https://doaj.org/article/2bf0ea4292564fe5adff19b2987b2889
Autor:
Wing Shan Yu, Anna Chung-Kwan Tse, Li Guan, Jennifer Lok Yu Chiu, Shawn Zheng Kai Tan, Sharafuddin Khairuddin, Stephen Kugbere Agadagba, Amy Cheuk Yin Lo, Man-Lung Fung, Ying-Shing Chan, Leanne Lai Hang Chan, Lee Wei Lim
Publikováno v:
Brain Stimulation, Vol 15, Iss 3, Pp 843-856 (2022)
Background: Given that visual impairment is bi-directionally associated with depression, we examined whether transcorneal electrical stimulation (TES), a non-invasive treatment for visual disorders, can ameliorate depressive symptoms. Objective: The
Externí odkaz:
https://doaj.org/article/696f7d04a6344fbc99e7ba7393cf1e20
Autor:
Shawn Zheng Kai Tan, Lee Wei Lim
Publikováno v:
IBRO Neuroscience Reports, Vol 11, Iss , Pp 52-55 (2021)
The pressures of the ethos of “publish or perish” in academia has led to a multitude of issues for science and scientists. In this paper, we argue that the existentialist philosophy concept of authenticity would be useful for scientists to preven
Externí odkaz:
https://doaj.org/article/4b3fb0249bdf4f1498a1dc5c8baa957e
Autor:
Shawn Zheng Kai Tan, Huseyin Kir, Brian D. Aevermann, Tom Gillespie, Nomi Harris, Michael J. Hawrylycz, Nikolas L. Jorstad, Ed S. Lein, Nicolas Matentzoglu, Jeremy A. Miller, Tyler S. Mollenkopf, Christopher J. Mungall, Patrick L. Ray, Raymond E. A. Sanchez, Brian Staats, Jim Vermillion, Ambika Yadav, Yun Zhang, Richard H. Scheuermann, David Osumi-Sutherland
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7751d67ab7c64803afd0caac5f39454a
Autor:
Shawn Zheng Kai Tan, Lee Wei Lim
Publikováno v:
BMC Medical Ethics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Recent advancements in neuroscientific techniques have allowed us to make huge progress in our understanding of memories, and in turn has paved the way for new memory modification technologies (MMTs) that can modulate memories wit
Externí odkaz:
https://doaj.org/article/17cae6bb6183447f995e95f6d30a26e3
Autor:
Shawn Zheng Kai Tan, Richard Du, Jose Angelo Udal Perucho, Shauhrat S. Chopra, Varut Vardhanabhuti, Lee Wei Lim
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Neuromodulation techniques such as deep brain stimulation (DBS) are a promising treatment for memory-related disorders including anxiety, addiction, and dementia. However, the outcomes of such treatments appear to be somewhat paradoxical, in that the
Externí odkaz:
https://doaj.org/article/908181e0eb734023a04c166c6c59c2d7
Autor:
Tatyana Strekalova, Ekaterina Veniaminova, Evgeniy Svirin, Ekaterina Kopeikina, Tatyana Veremeyko, Amanda W. Y. Yung, Andrey Proshin, Shawn Zheng Kai Tan, Sharafuddin Khairuddin, Lee Wei Lim, Klaus-Peter Lesch, Susanne Walitza, Daniel C. Anthony, Eugene D. Ponomarev
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1759 (2021)
A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology, including epilepsy and metabolic abnormalities. Disruption of ganglioside production by this en
Externí odkaz:
https://doaj.org/article/b5aba7368ea34b16b074c8815ed02464
Publikováno v:
Viruses, Vol 8, Iss 2, p 24 (2016)
Saffold Virus (SAFV) is a human cardiovirus that has been suggested to cause severe infection of the central nervous system (CNS). Compared to a similar virus, Theiler’s murine encephalomyelitis virus (TMEV), SAFV has a truncated Leader (L) protein
Externí odkaz:
https://doaj.org/article/c35aefe189a64fcd82a0747ec264c259