Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shawn X. Yin"'
Autor:
Lei Wei, Wei Wang, Le Xu, Tianqiong Ma, Junliang Sun, Yue-Biao Zhang, Jing Niu, Xiaoge Wang, Lin Liang, Huadong Xue, Shawn X. Yin
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Crystal size effect is of vital importance in materials science by exerting significant influence on various properties of materials and furthermore their functions. Crystal size effect of covalent organic frameworks (COFs) has never been reported be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7440cc0ed52c67f70c40778eecac966
http://europepmc.org/articles/PMC7705719
http://europepmc.org/articles/PMC7705719
Publikováno v:
Molecular Pharmaceutics. 14:377-385
A generalized screening approach, applying isothermal calorimetry at 37 °C 100% RH, to formulations of spray dried dispersions (SDDs) for two active pharmaceutical ingredients (APIs) (BMS-903452 and BMS-986034) is demonstrated. APIs 452 and 034, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f88575f0b50119e992ee2411f70a780
https://doi.org/10.1021/acs.molpharmaceut.6b00722
https://doi.org/10.1021/acs.molpharmaceut.6b00722
Autor:
Jing Niu, Li-Hua Li, Omar M. Yaghi, Lin Liang, Wang Yingying, Eugene A. Kapustin, Junliang Sun, Wei David Wang, Jian Li, Tianqiong Ma, Xiaoge Wang, Shawn X. Yin, Wei Wang, Zhengyang Zhou, Jie Su
Publikováno v:
Science (New York, N.Y.). 361(6397)
Covalent organic frameworks writ large Covalent organic framework (COF) materials have been difficult to characterize structurally and to exploit because they tend to form powders or amorphous materials. Ma et al. studied a variety of three-dimension
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c109a8df3dfb59f2f882867a0bb08fbf
https://pubmed.ncbi.nlm.nih.gov/29976816
https://pubmed.ncbi.nlm.nih.gov/29976816
Publikováno v:
Crystal Growth & Design. 14:5004-5010
A new crystalline polymorph (Form VIII) of the antidepressant drug aripiprazole has been discovered, resulting from a previously unknown enantiotropic phase transition from Form II at 225 K. This finding makes aripiprazole one of the most polymorphic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85e87ebb26d786f0b75bd7ce510862a6
https://doi.org/10.1021/cg500569x
https://doi.org/10.1021/cg500569x
Molecular Basis of Crystal Morphology-Dependent Adhesion Behavior of Mefenamic Acid During Tableting
Autor:
Vrushali Waknis, Schlam Roxana F, Elza Chu, Alexander Sidorenko, Ajit S. Narang, Shawn X. Yin, Sherif Badawy
Publikováno v:
Pharmaceutical Research. 31:160-172
The molecular basis of crystal surface adhesion leading to sticking was investigated by exploring the correlation of crystal adhesion to oxidized iron coated atomic force microscope (AFM) tips and bulk powder sticking behavior during tableting of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7aef208baaeb624fc21bfb654e10530
https://doi.org/10.1007/s11095-013-1149-6
https://doi.org/10.1007/s11095-013-1149-6
Publikováno v:
Crystal Growth & Design. 13:2943-2952
The relative stabilities of crystalline polymorphs are an important aspect of the manufacturing and effective utilization of pharmaceuticals. These stabilities are driven by both molecular conformational energy within the solid-state components and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39235d6f054bb4c48c7b5c5bfe2f880e
https://doi.org/10.1021/cg400358e
https://doi.org/10.1021/cg400358e
Publikováno v:
Crystal Growth & Design. 12:5017-5024
The characterization of crystalline polymorphs of drug molecules is an area of great interest since these variations in solid-state structure directly influence the physical properties of such substances. Terahertz spectroscopy provides a powerful an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f564ebc7d92569c3fd7061a4ad270c
https://doi.org/10.1021/cg300977e
https://doi.org/10.1021/cg300977e
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 66:221-235
Saccharides, including sucrose, trehalose, mannitol, and sorbitol, are commonly employed as stabilizers, cryoprotectants, and/or tonicity adjusters in protein formulations. During the thawing of a protein-containing formulated bulk drug substance con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e56535e2e4efac3b4977f60d0adcf8
https://doi.org/10.5731/pdajpst.2012.00861
https://doi.org/10.5731/pdajpst.2012.00861
Autor:
Michael G. Fakes, Andrew B. Dennis, Peter Timmins, Gary McGeorge, Chhaya Patel, John F. Gamble, Jonathan Brown, Shawn X. Yin, Yaroslav Z. Khimyak, Mike Tobyn, Gao Qi, Wayne Sinclair
Publikováno v:
Journal of Pharmaceutical Sciences. 98:3456-3468
We report the case of BMS-488043-PVP solid dispersions which when analysed using modulated DSC showed compliance with the Gordon–Taylor model, confirming ideal mixing behaviour of the two components. The nature or presence of stabilising interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfde282f283dd37bb71e6a9f1011cc81
https://doi.org/10.1002/jps.21738
https://doi.org/10.1002/jps.21738
Autor:
Ronald L. Smith, Munir A. Hussain, Alice Hsieh, Miriam K. Franchini, Sandy Jen, Jinling Chen, Shawn X. Yin, Tu Lee
Publikováno v:
Journal of Pharmaceutical Sciences. 94:1598-1607
Spray drying drug with excipients is usually associated with the preparation of microcrystalline or amorphous drug in order to improve bioavailability. It was found that BMS-347070, when spray-dried with Pluronic F127 from acetone or methylene chlori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604d9f96414eb4c0b81810666a4cf098
https://doi.org/10.1002/jps.20366
https://doi.org/10.1002/jps.20366