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pro vyhledávání: '"Shawn William Jones"'
Publikováno v:
Journal of Bacteriology. 193:5130-5137
In order to better characterize the initial stages of sporulation past Spo0A activation and the associated solventogenesis in the important industrial and model organism Clostridium acetobutylicum , the spoIIE gene was successfully disrupted and its
Publikováno v:
Journal of Bacteriology. 193:2429-2440
Clostridium acetobutylicum is both a model organism for the understanding of sporulation in solventogenic clostridia and its relationship to solvent formation and an industrial organism for anaerobic acetone-butanol-ethanol (ABE) fermentation. How so
Publikováno v:
Journal of Bacteriology. 193:1414-1426
Clostridium is a diverse genus of obligate anaerobic, endospore-forming, Gram-positive bacteria. Pathogenic species such as C. botulinum, C. difficile, C. perfringens, and C. tetani produce upwards of 18% of all known bacterial toxins, thus making Cl
Autor:
Dinesh C. Indurthi, Eleftherios T. Papoutsakis, Jacob R. Borden, Shawn William Jones, Yili Chen
Publikováno v:
Metabolic Engineering. 12:268-281
We generated a genomic library from sheared Clostridium acetobutylicum ATCC 824 DNA, whereby inserts can be expressed in both directions from the thiolase promoter, P(thl). Serial transfer of library-bearing C. acetobutylicum cultures exposed to incr
Autor:
Kelvin H. Lee, E. Terry Papoutsakis, Matthew T. Ralston, Shuyu Hou, Keerthi P. Venkataramanan, Lie Min, Shawn William Jones
Publikováno v:
Biotechnology for Biofuels
Background Clostridium acetobutylicum is a model organism for both clostridial biology and solvent production. The organism is exposed to its own toxic metabolites butyrate and butanol, which trigger an adaptive stress response. Integrative analysis
Autor:
Jungik Choi, Shawn William Jones, Jennifer Au, Keerthi P. Venkataramanan, Maciek R. Antoniewicz
Publikováno v:
Metabolic engineering. 26
In this work, we provide new insights into the metabolism of Clostridium acetobutylicum ATCC 824 obtained using a systematic approach for quantifying fluxes based on parallel labeling experiments and (13)C-metabolic flux analysis ((13)C-MFA). Here, c
Autor:
Ryan S. Senger, Shawn William Jones, Ryan Sillers, Jacob R. Borden, Eleftherios T. Papoutsakis, Carlos J. Paredes
This chapter focuses on the regulation of solvent formation in solventogenic clostridia and in particular in Clostridium acetobutylicum ATCC 824, the most widely studied solventogenic Clostridium at a genetic level, and until recently the only sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50291dd5b10c0c3f9b2bed188191ff1f
https://doi.org/10.1128/9781555815547.ch25
https://doi.org/10.1128/9781555815547.ch25
Publikováno v:
mBio, Vol 2, Iss 1 (2011)
mBio
mBio
The genus Clostridium includes major human pathogens and species important to cellulose degradation, the carbon cycle, and biotechnology. Small RNAs (sRNAs) are emerging as crucial regulatory molecules in all organisms, but they have not been investi
Autor:
Kevin McCormick, Keerthi P. Venkataramanan, Matthew T. Ralston, Sridhara G. Kunjeti, Eleftherios T. Papoutsakis, Shawn William Jones, Blake C. Meyers
Publikováno v:
BMC Genomics
Background Small non-coding RNAs (sRNA) are emerging as major components of the cell’s regulatory network, several possessing their own regulons. A few sRNAs have been reported as being involved in general or toxic-metabolite stress, mostly in Gram
Autor:
Bryan P. Tracy, Eleftherios T. Papoutsakis, Nathan Cheng, Ryan S. Senger, Carlos J. Paredes, Ryan Sillers, Shawn William Jones
Publikováno v:
Genome Biology
A detailed microarray analysis of transcription during sporulation of the strict anaerobe and endospore former Clostridium acetobutylicum is presented.
Background Clostridia are ancient soil organisms of major importance to human and animal heal
Background Clostridia are ancient soil organisms of major importance to human and animal heal