Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shawn W. Flanagan"'
Publikováno v:
Journal of Neurochemistry. 102:609-618
Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease in adults, is characterized by the selective degeneration and death of motor neurons leading to progressive paralysis and eventually death. Approximately 20% of familial ALS ca
Autor:
Sujatha Venkataraman, Freya Q. Schafer, Hannah J. Zhang, Min Wang, Douglas R. Spitz, Larry W. Oberley, Garry R. Buettner, Christine J. Weydert, Frederick E. Domann, Shawn W. Flanagan, Jeanie S Kirk
Publikováno v:
Oncogene. 24:8154-8166
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that governs cellular responses to reduced O2 availability by mediating crucial homeostatic processes. HIF-1 is composed of an HIF-1alpha subunit and an HIF-1beta subunit. HIF-1alpha is deg
Autor:
Julia E. Sim, Ryuji Higashikubo, Garry R. Buettner, Sujatha Venkataraman, Nukhet Aykin-Burns, Shawn W. Flanagan, Douglas R. Spitz, Michael A. Mackey, Susan A. Walsh, Larry W. Oberley, Iman M. Ahmad
Publikováno v:
Journal of Biological Chemistry. 280:4254-4263
The hypothesis that glucose deprivation-induced cytotoxicity in transformed human cells is mediated by mitochondrial O2*- and H2O2 was first tested by exposing glucose-deprived SV40-transformed human fibroblasts (GM00637G) to electron transport chain
Publikováno v:
Journal of Neurochemistry. 81:170-177
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor function and eventual death as a result of degeneration of motor neurons in the spinal cord and brain. The discovery of mutations in SOD1, t
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 3:103-107
We investigated the use of an interstitial temperature self-regulating implant for fractionated hyperthermia delivery for treatment of prostatic disease. Nonuniform heating, lower temperatures between the implants, and lingering thermotolerance for a
Autor:
Sara A. Romig-Martin, Tapan K Chaterjee, Lynn L. Stoll, Eric W. Dickson, Shawn W Flanagan, Neal L. Weintraub, Laynez W. Ackermann, Gerene M. Denning
Publikováno v:
The FASEB Journal. 22
Publikováno v:
Journal of neurochemistry. 102(3)
Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease in adults, is characterized by the selective degeneration and death of motor neurons leading to progressive paralysis and eventually death. Approximately 20% of familial ALS ca
Autor:
Iman M, Ahmad, Nukhet, Aykin-Burns, Julia E, Sim, Susan A, Walsh, Ryuji, Higashikubo, Garry R, Buettner, Sujatha, Venkataraman, Michael A, Mackey, Shawn W, Flanagan, Larry W, Oberley, Douglas R, Spitz
Publikováno v:
The Journal of biological chemistry. 280(6)
The hypothesis that glucose deprivation-induced cytotoxicity in transformed human cells is mediated by mitochondrial O2*- and H2O2 was first tested by exposing glucose-deprived SV40-transformed human fibroblasts (GM00637G) to electron transport chain
Publikováno v:
Journal of endourology. 11(4)
An interstitial temperature self-regulating implantable thermal seed for ablation of the prostate was investigated for the treatment of cancer. The technique is analogous to brachytherapy implants with three important advantages: highly localized tem
Publikováno v:
The American journal of physiology. 268(1 Pt 2)
Heatstroke is a multisystem disorder that can result in death. Activities that increase the rate of heat storage predispose an organism to thermal injury. Using a 72-kDa heat shock protein (HSP72) as a marker of thermal injury, we determined 1) which