Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shawn R. Makinen"'
Autor:
Felicity C. Stark, Bassel Akache, Lise Deschatelets, Anh Tran, Matthew Stuible, Yves Durocher, Michael J. McCluskie, Gerard Agbayani, Renu Dudani, Blair A. Harrison, Tyler M. Renner, Shawn R. Makinen, Jegarubee Bavananthasivam, Diana Duque, Martin Gagne, Joseph Zimmermann, C. David Zarley, Terrence R. Cochrane, Martin Handfield
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract With the persistence of the SARS-CoV-2 pandemic and the emergence of novel variants, the development of novel vaccine formulations with enhanced immunogenicity profiles could help reduce disease burden in the future. Intranasally delivered v
Externí odkaz:
https://doaj.org/article/75d13e574ac142e0965e0c8633e1ee5d
Autor:
Bassel Akache, Andrew J. Read, Renu Dudani, Blair A. Harrison, Dean Williams, Lise Deschatelets, Yimei Jia, Vandana Chandan, Felicity C. Stark, Gerard Agbayani, Shawn R. Makinen, Usha D. Hemraz, Edmond Lam, Sophie Régnier, Wei Zou, Peter D. Kirkland, Michael J. McCluskie
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1043 (2023)
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen. Rabbit hemorrhagic disease virus (RHDV)
Externí odkaz:
https://doaj.org/article/8033a136f9c84c7da76024c305c13447
Autor:
Felicity C. Stark, Bassel Akache, Lise Deschatelets, Anh Tran, Matthew Stuible, Yves Durocher, Michael J. McCluskie, Gerard Agbayani, Renu Dudani, Blair A. Harrison, Tyler M. Renner, Shawn R. Makinen, Jegarubee Bavananthasivam, Diana Duque, Martin Gagne, Joseph Zimmermann, C. David Zarley, Terrence R. Cochrane, Martin Handfield
With the persistence of the SARS-CoV-2 pandemic and the emergence of novel variants, the development of novel vaccine formulations with enhanced immunogenicity profiles could help reduce disease burden in the future. Intranasally delivered vaccines o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41097619cc9155cdf1fc6e640462c430
https://doi.org/10.1101/2022.03.02.482651
https://doi.org/10.1101/2022.03.02.482651
Publikováno v:
International Immunology. 28:453-461
Adjuvants are a key component in enhancing immunogenicity of vaccines and play a vital role in facilitating the induction of the correct type of immunity required for each vaccine to be optimally efficacious. Several different adjuvants are found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee7e05890daa6e13d349659ca198a4e
https://doi.org/10.1093/intimm/dxw017
https://doi.org/10.1093/intimm/dxw017
Autor:
Julia Li, J. Erik Johnson, Derek John Falconer, Kate West, Kathrin U. Jansen, Oscar Maldonado, Susanne Lang, Jim E. Eyles, Cheryl S. Kotash, Shawn R. Makinen, Phil White, Risini D. Weeratna, James R. Merson, Thomas P. Brown, Paul Wright, George J. Smith, Clare Lees, Susan E. Witko, Paul Cockle, Vidia Roopchand, Peter T. Loudon, Shakuntala Megati, Maninder K. Sidhu
Publikováno v:
Journal of Infectious Diseases. 208:319-329
Background. We evaluated the immunological responses of African green monkeys immunized with multiple F and G protein–based vaccines and assessed protection against the Memphis 37 strain of respiratory syncytial virus (RSV). Methods. Monkeys were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d322dd2583760ad8a2e105c4aaeac2a
https://doi.org/10.1093/infdis/jit169
https://doi.org/10.1093/infdis/jit169
Autor:
Bruce A. Green, Richard J. Anderson, Derek John Falconer, Neil C. Sheppard, Shawn R. Makinen, Anne-Laure Goenaga, Stephen J. Gracheck, Jim E. Eyles, James R. Merson, Risini D. Weeratna, Susanne Lang, Siradanahalli Guru, Bingsheng Chang
Publikováno v:
Vaccine. 34(50)
We evaluated 52 different E. coli expressed pneumococcal proteins as immunogens in a BALB/c mouse model of S. pneumoniae lung infection. Proteins were selected based on genetic conservation across disease-causing serotypes and bioinformatic predictio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0e1d47c7a0000dc87f3533c4098fdd
https://pubmed.ncbi.nlm.nih.gov/27816374
https://pubmed.ncbi.nlm.nih.gov/27816374
Publikováno v:
Vaccine. 23:5263-5270
TLR ligands that mimic pathogen associated molecular patterns and activate immune cells via Toll-like receptors (TLRs) are being developed for use in humans as therapy against a variety of diseases as well as vaccine adjuvants. These include imidazoq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc91eb12f256b4b8162c11f29ef01935
https://doi.org/10.1016/j.vaccine.2005.06.024
https://doi.org/10.1016/j.vaccine.2005.06.024
Autor:
Heather L. Davis, Risini D. Weeratna, Michael J. McCluskie, Debbie Drane, Dana M. Evans, Shawn R. Makinen
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2013 (2013)
BioMed Research International, Vol 2013 (2013)
For the induction of robust humoral and cellular immune responses, a strong rationale exists to use vaccine-adjuvant combinations possessing both immune modulatory and enhanced delivery capabilities. Herein, we evaluated the combination of 2 differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc57fcb3a96e0f26824e4ce5ea9bdbe
Autor:
Rachel Luu, Alain Vicari, Ningli Zhang, Shawn R. Makinen, Risini D. Weeratna, Douglas C. Hanson, Shobhna Patel, Arthur M. Krieg
Publikováno v:
Cancer immunology, immunotherapy : CII. 58(4)
The anti-tumor properties of Toll-like receptor (TLR) 9 agonist CpG oligodeoxynucleotides (ODN) are enhanced by combinations with several cytotoxic chemotherapy regimens. The mechanisms of this added benefit, however, remain unclear. We now report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2013a7c653fffa93bd8ba6aea8106dbd
https://pubmed.ncbi.nlm.nih.gov/18802696
https://pubmed.ncbi.nlm.nih.gov/18802696