Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Shawn R. Lockery"'
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
The nematode Caenorhabditis elegans is a model organism widely used in basic, translational, and industrial research. C. elegans development is characterized by five morphologically distinct stages, including four larval stages and the adult stage. S
Externí odkaz:
https://doaj.org/article/8b58d114ca2b46119e429fedbb3ed963
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 3, Pp 607-628 (2018)
Many anthelmintic drugs used to treat parasitic nematode infections target proteins that regulate electrical activity of neurons and muscles: ion channels (ICs) and neurotransmitter receptors (NTRs). Perturbation of IC/NTR function disrupts worm beha
Externí odkaz:
https://doaj.org/article/286a466f2263460fb3293d93f3cfe018
Autor:
Janis C. Weeks, William M. Roberts, Kristin J. Robinson, Melissa Keaney, Jon J. Vermeire, Joseph F. Urban Jr., Shawn R. Lockery, John M. Hawdon
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 314-328 (2016)
The screening of candidate compounds and natural products for anthelmintic activity is important for discovering new drugs against human and animal parasites. We previously validated in Caenorhabditis elegans a microfluidic device (‘chip’) that r
Externí odkaz:
https://doaj.org/article/9f476598198d4afa81ee0b1d6df29faa
Autor:
Abraham Katzen, Hui-Kuan Chung, William T Harbaugh, Christina Della Iacono, Nicholas Jackson, Elizabeth E Glater, Charles J Taylor, Stephanie K Yu, Steven W Flavell, Paul W Glimcher, James Andreoni, Shawn R Lockery
Publikováno v:
eLife. 12
In value-based decision making, options are selected according to subjective values assigned by the individual to available goods and actions. Despite the importance of this faculty of the mind, the neural mechanisms of value assignments, and how cho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789908e633d7be355dd85a819c5d5d0a
https://doi.org/10.7554/elife.69779
https://doi.org/10.7554/elife.69779
Autor:
Abraham Katzen, Hui-Kuan Chung, William T Harbaugh, Christina Della Iacono, Nicholas Jackson, Elizabeth E Glater, Charles J Taylor, Stephanie K Yu, Steven W Flavell, Paul W Glimcher, James Andreoni, Shawn R Lockery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a89649cdd3ae2e6508b88ee2dd57102
https://doi.org/10.7554/elife.69779.sa2
https://doi.org/10.7554/elife.69779.sa2
The nematodeCaenorhabditis elegansis a model organism widely used in basic, translational, and industrial research.C. elegansdevelopment is characterized by five morphologically distinct stages, including four larval stages and the adult stage. Stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccada89dde1677056acaa2d79599970b
https://doi.org/10.1101/2023.01.07.523116
https://doi.org/10.1101/2023.01.07.523116
Autor:
Anastasia Levichev, Serge Faumont, Rachel Z. Berner, Zhifeng Purcell, Amanda M. White, Kathy Chicas-Cruz, Shawn R. Lockery
Publikováno v:
Current Biology. 33:1625-1639.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c8f35a369f831d31381ece8f16a18c9
https://doi.org/10.1016/j.cub.2023.03.013
https://doi.org/10.1016/j.cub.2023.03.013
Autor:
William M Roberts, Steven B Augustine, Kristy J Lawton, Theodore H Lindsay, Tod R Thiele, Eduardo J Izquierdo, Serge Faumont, Rebecca A Lindsay, Matthew Cale Britton, Navin Pokala, Cornelia I Bargmann, Shawn R Lockery
Publikováno v:
eLife, Vol 5 (2016)
Random search is a behavioral strategy used by organisms from bacteria to humans to locate food that is randomly distributed and undetectable at a distance. We investigated this behavior in the nematode Caenorhabditis elegans, an organism with a smal
Externí odkaz:
https://doaj.org/article/d0e956e330cb4893868cfb3fbb174f5e
Publikováno v:
Biomicrofluidics. 17:014103
The nematode worm C. elegans is widely used in basic and translational research. The creation of transgenic strains by injecting DNA constructs into the worm’s gonad is an essential step in many C. elegans research projects. This paper describes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ef6af758360adc5d3ee9d5457de15a
https://doi.org/10.1063/5.0130806
https://doi.org/10.1063/5.0130806
The mammalian endocannabinoid system, comprised of the endocannabinoids AEA (N-arachidonoyl-ethanolamine) and 2-AG (2-Arachidonoylglycerol), their receptors, CB1 and CB2, and their metabolic enzymes, is believed to integrate internal energy state and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2d1d052c7d736c3a7926ed467d968d
https://doi.org/10.1101/2021.05.13.444082
https://doi.org/10.1101/2021.05.13.444082