Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Shawn N. Whitehead"'
Autor:
Mariyan J. Jeyarajah, Violet S. Patterson, Gargi Jaju Bhattad, Lin Zhao, Shawn N. Whitehead, Stephen J. Renaud
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Congenital heart defects are leading causes of neonatal mortality and are often associated with placental abnormalities, but mechanisms linking placenta and heart development are poorly understood. Herein, we investigated a potential signali
Externí odkaz:
https://doaj.org/article/6a1a723dd94140c984e20c6725f39a69
Autor:
Sarah H. Hayes, Salonee V. Patel, Parinita Arora, Lin Zhao, Ashley L. Schormans, Shawn N. Whitehead, Brian L. Allman
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106619- (2024)
It is well established that hearing loss can lead to widespread plasticity within the central auditory pathway, which is thought to contribute to the pathophysiology of audiological conditions such as tinnitus and hyperacusis. Emerging evidence sugge
Externí odkaz:
https://doaj.org/article/9dcddd664e00451093076a703412871e
Autor:
Marta De Felice, Hanna J. Szkudlarek, Taygun C. Uzuneser, Mar Rodríguez-Ruiz, Mohammed H. Sarikahya, Mathusha Pusparajah, Juan Pablo Galindo Lazo, Shawn N. Whitehead, Ken K.-C. Yeung, Walter J. Rushlow, Steven R. Laviolette
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 6, Pp 100361- (2024)
Background: Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerability, including mood- and anxiety-related symptoms. The psychotropic effects of THC on affect and anxiogenic behavioral phen
Externí odkaz:
https://doaj.org/article/27928f2b63ef418698a78cd70f62b509
Autor:
Paulina M. Kowalewska, Justin E. Piazza, Stephanie L. Milkovich, Richard J. Sové, Lin Wang, Shawn N. Whitehead, Christopher G. Ellis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Sepsis is a dysregulated host inflammatory response to infection potentially leading to life-threatening organ dysfunction. The objectives of this study were to determine whether early microvascular dysfunction (MVD) in skeletal muscle can b
Externí odkaz:
https://doaj.org/article/2882ed0426464ea382735ea599cf8c8a
Autor:
Salonee V. Patel, Courtney M. DeCarlo, Shae A. Book, Ashley L. Schormans, Shawn N. Whitehead, Brian L. Allman, Sarah H. Hayes
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Hearing loss is a chronic health condition that affects millions of people worldwide. In addition to age-related hearing impairment, excessive noise exposure is a leading cause of hearing loss. Beyond the devastating effects of hearing impairment its
Externí odkaz:
https://doaj.org/article/04830ed465ad4c9f8e625668deb0e407
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Cognitive impairment involves complex interactions between multiple pathways and mechanisms, one of which being cardiac disorders. Atrial cardiopathy (AC) is a structural and functional disorder of the left atrium that may be a substrate for other ca
Externí odkaz:
https://doaj.org/article/d08c5ca34ae949bdafcc0f3a6badc5e0
Autor:
Nassir U. Al-Khishman, Qi Qi, Austyn D. Roseborough, Alexander Levit, Brian L. Allman, Udunna C. Anazodo, Matthew S. Fox, Shawn N. Whitehead, Jonathan D. Thiessen
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Accurate and sensitive imaging biomarkers are required to study the progression of white matter (WM) inflammation in neurodegenerative diseases. Radioligands targeting the translocator protein (TSPO) are considered sensitive indic
Externí odkaz:
https://doaj.org/article/473f864de7004a0b9389d7c350f32306
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 15 (2021)
Altered sensory information processing, and auditory processing, in particular, is a common impairment in individuals with autism spectrum disorder (ASD). One prominent hypothesis for the etiology of ASD is an imbalance between neuronal excitation an
Externí odkaz:
https://doaj.org/article/b932fb5049514f469e55e46b705cc914
Autor:
Nikita Ollen-Bittle, Austyn D. Roseborough, Wenxuan Wang, Jeng-liang D. Wu, Shawn N. Whitehead
Publikováno v:
Biology, Vol 11, Iss 8, p 1231 (2022)
Stoke is a prevalent and devastating neurologic condition with limited options for therapeutic management. Since brain tissue is rarely accessible clinically, peripheral biomarkers for the central nervous system’s (CNS’s) cellular response to str
Externí odkaz:
https://doaj.org/article/0423a9c0986a489588abd1c4504b0ccb
Autor:
Alexander Levit, Sonny Cheng, Olivia Hough, Qingfan Liu, Yuksel Agca, Cansu Agca, Vladimir Hachinski, Shawn N. Whitehead
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Hypertension is recognized as a risk factor for Alzheimer disease, but the causal link remains undetermined. Although astrocytes and microglia play an important role in maintaining the neurovascular unit, astrocytes and microglia have been understudi
Externí odkaz:
https://doaj.org/article/00c19104ec884a9099fd1f494c73d4f8