Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shawn M. Sprague"'
Autor:
Koichi Kawakami, Louis Saint-Amant, Kazutoyo Ogino, John Y. Kuwada, Kazuhide Asakawa, Yuriko Naganawa, Yu Kawakami, Hiromi Hirata, Weibin Zhou, Kenta Yamada, Sean E. Low, Hua Wen, Akira Muto, Shawn M. Sprague, Wilson W. Cui
Publikováno v:
Journal of Biological Chemistry. 287:1080-1089
In many tissues and organs, connexin proteins assemble between neighboring cells to form gap junctions. These gap junctions facilitate direct intercellular communication between adjoining cells, allowing for the transmission of both chemical and elec
Autor:
Jeremy W. Linsley, Louis Saint-Amant, Wilson W. Cui, Richard I. Hume, Eric J. Horstick, Kimberly Amburgey, Weibin Zhou, John Y. Kuwada, Hiromi Hirata, Sean E. Low, Shawn M. Sprague
Publikováno v:
The Journal of Neuroscience. 31:11633-11644
Mutations in the gene encoding TRPM7 (trpm7), a member of the Transient Receptor Potential (TRP) superfamily of cation channels that possesses an enzymatically active kinase at its C terminus, cause the touch-unresponsive zebrafish mutanttouchdown. W
Autor:
Qin Li, Louis Saint-Amant, Olivier Poudou, Richard I. Hume, Shawn M. Sprague, Wilson W. Cui, Weibin Zhou, John Y. Kuwada, Hiromi Hirata
Publikováno v:
Developmental Neurobiology. 68:45-61
The zebrafish ennui mutation was identified from a mutagenesis screen for defects in early behavior. Homozygous ennui embryos swam more slowly than wild-type siblings but normal swimming recovered during larval stages and homozygous mutants survived
Autor:
Cynthia M. Powell, Eric J. Horstick, Michael A. Hauser, Jeremy W. Linsley, John Y. Kuwada, Hiromi Hirata, Marcy C. Speer, Kristin K. McDonald, Wilson W. Cui, Akhila G. Satish, Allison E. Ashley-Koch, Weibin Zhou, James J. Dowling, Shawn M. Sprague, Demetra S. Stamm, Clara Franzini-Armstrong, Louis Saint-Amant
Publikováno v:
Nature communications
Excitation-contraction coupling, the process that regulates contractions by skeletal muscles, transduces changes in membrane voltage by activating release of Ca(2+) from internal stores to initiate muscle contraction. Defects in excitation-contractio
Autor:
Joel Ryan, Weibin Zhou, Hiromi Hirata, Wilson W. Cui, Richard I. Hume, Shawn M. Sprague, John Y. Kuwada, Louis Saint-Amant, Sean E. Low
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(28)
The process by which light touch in vertebrates is transformed into an electrical response in cutaneous mechanosensitive neurons is a largely unresolved question. To address this question we undertook a forward genetic screen in zebrafish (Danio reri
Autor:
Sean E. Low, Ingxin Choong, Weibin Zhou, Wilson W. Cui, Richard I. Hume, Shawn M. Sprague, Hiromi Hirata, John Y. Kuwada, Louis Saint-Amant
Publikováno v:
Developmental Neurobiology.
A screen for zebrafish motor mutants identified two noncomplementing alleles of a recessive mutation that were named non-active (nav(mi89) and nav(mi130)). nav embryos displayed diminished spontaneous and touch-evoked escape behaviors during the firs
Autor:
John Y. Kuwada, Wilson W. Cui, Takaki Watanabe, Louis Saint-Amant, Jun Hatakeyama, Hiromi Hirata, Weibin Zhou, Ayako Nagashima, Shawn M. Sprague
Publikováno v:
Development (Cambridge, England). 134(15)
Wild-type zebrafish embryos swim away in response to tactile stimulation. By contrast, relatively relaxed mutants swim slowly due to weak contractions of trunk muscles. Electrophysiological recordings from muscle showed that output from the CNS was n
Autor:
Louis Saint-Amant, Wilson W. Cui, John Y. Kuwada, Shawn M. Sprague, Weibin Zhou, Hiromi Hirata
Publikováno v:
Cell calcium. 39(3)
Contractions by skeletal muscle require proper excitation-contraction (EC) coupling, whereby depolarization of the muscle membrane leads to an increase in cytosolic Ca(2+) and contraction. Changes in membrane voltage are detected by dihydropyridine r