Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shawn M. O'Hara"'
Development of Monoclonal Antibodies to the Malondialdehyde−Deoxyguanosine Adduct, Pyrimidopurinone1
Autor:
Norma H. Mahle, Naomi Eliezer, Lawrence J. Marnett, Cynthia L. Sevilla, Shawn M. O'Hara, Ryan J. Miller, Munetaka Nokubo, Adam Uzieblo, Carol A. Rouzer
Publikováno v:
Chemical Research in Toxicology. 10:172-180
Malondialdehyde (MDA), an endogenous product of lipid peroxidation and prostaglandin biosynthesis, is mutagenic in bacterial and mammalian cells and carcinogenic in rats. In order to determine whether MDA-modified bases are formed in nucleic acids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::927a2c12b0b173101a2b27396755fc5d
https://doi.org/10.1021/tx960120d
https://doi.org/10.1021/tx960120d
Autor:
Lawrence J. Marnett, Shawn M. O'Hara
Publikováno v:
Mutation research. 247(1)
The histidine auxotroph hisD3052 results from a single base-pair deletion (C:G) from the 298th codon (alanine) in the D gene of the histidine operon of S. typhimurium LT-2. Bacteria carrying this mutation revert to histidine prototrophy by frameshift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e34a1aa28706da2497609bd33d3760
https://pubmed.ncbi.nlm.nih.gov/2002804
https://pubmed.ncbi.nlm.nih.gov/2002804
Publikováno v:
Chemical Research in Toxicology. 1:53-59
Malondialdehyde and a series of acrolein derivatives substituted in the beta-position with good leaving groups react with guanine and guanine nucleosides to form two different types of adducts. The reaction with guanosine is typical. One adduct exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8e4f711c74cc9ce3822b420db81987
https://doi.org/10.1021/tx00001a010
https://doi.org/10.1021/tx00001a010
Autor:
A. F. M. Maqsudur. Rahman, Lawrence J. Marnett, Paul E. Weller, Ashis K. Basu, John P. Oliver, Shawn M. O'Hara
Publikováno v:
Journal of the American Chemical Society. 108:1348-1350
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375c735f09a6b71f79be10402332fe9a
https://doi.org/10.1021/ja00266a065
https://doi.org/10.1021/ja00266a065
Autor:
John P. Oliver, Abdul Rahman, Paul E. Weller, Lawrence J. Marnett, Ashis K. Basu, Shawn M. O'Hara
Publikováno v:
Chemischer Informationsdienst. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f955d366ae47c4ccc7bd6584f45d412b
https://doi.org/10.1002/chin.198629321
https://doi.org/10.1002/chin.198629321