Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shawn M. Lyons"'
Autor:
Yuan Gao, Julian Kwan, Joseph Orofino, Giulia Burrone, Sahana Mitra, Ting-Yu Fan, Justin English, Ryan Hekman, Andrew Emili, Shawn M. Lyons, Maria Dafne Cardamone, Valentina Perissi
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107336- (2024)
G-Protein Pathway Suppressor 2 (GPS2) is an inhibitor of non-proteolytic K63 ubiquitination mediated by the E2 ubiquitin-conjugating enzyme Ubc13. Previous studies have associated GPS2-mediated restriction of ubiquitination with the regulation of ins
Externí odkaz:
https://doaj.org/article/13b49b296d094f39b10df53c79baaeb6
Autor:
Yasutoshi Akiyama, Shawn M. Lyons, Marta M. Fay, Yoshihisa Tomioka, Takaaki Abe, Paul J. Anderson, Pavel Ivanov
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Stress-induced tRNA cleavage has been implicated in various cellular processes, where tRNA fragments play diverse regulatory roles. Angiogenin (ANG), a member of the RNase A superfamily, induces cleavage of tRNAs resulting in the formation of tRNA-de
Externí odkaz:
https://doaj.org/article/5aeb2346071c4703bb21e9e8b55d3354
Autor:
Paulina Pietras, Anaïs Aulas, Marta M. Fay, Marta Leśniczak-Staszak, Mateusz Sowiński, Shawn M. Lyons, Witold Szaflarski, Pavel Ivanov
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 145, Iss , Pp 112382- (2022)
Platinum-based antineoplastic drugs, such as cisplatin, are commonly used to induce tumor cell death. Cisplatin is believed to induce apoptosis as a result of cisplatin-DNA adducts that inhibit DNA and RNA synthesis. Although idea that DNA damage und
Externí odkaz:
https://doaj.org/article/e1950fe9973046578127c4bb440eb387
Autor:
Nikita Fernandes, Luke Nero, Shawn M. Lyons, Pavel Ivanov, Telsa M. Mittelmeier, Timothy A. Bolger, J. Ross Buchan
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1895 (2021)
In the original article [...]
Externí odkaz:
https://doaj.org/article/08af0e10d83e40aa9dc04dbcd1844ac1
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
RNA G-quadruplexes (RG4) occur in vivo and have regulatory roles in mRNA metabolism. Here the authors show that the guanine residue stretches at the 5’ end of tRNA-derived stress-induced RNAs mediate the formation of tetramolecular RG4 structures,
Externí odkaz:
https://doaj.org/article/cba8c36886fd443aa55acf7c6f648780
Autor:
Marco Mineo, Franz Ricklefs, Arun K. Rooj, Shawn M. Lyons, Pavel Ivanov, Khairul I. Ansari, Ichiro Nakano, E. Antonio Chiocca, Jakub Godlewski, Agnieszka Bronisz
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2500-2509 (2016)
Long non-coding RNAs (lncRNAs) have an undefined role in the pathobiology of glioblastoma multiforme (GBM). These tumors are genetically and phenotypically heterogeneous with transcriptome subtype-specific GBM stem-like cells (GSCs) that adapt to the
Externí odkaz:
https://doaj.org/article/0acd0d2cd2a648f98bc5c0f9809c6463
Autor:
Nikita Fernandes, Luke Nero, Shawn M. Lyons, Pavel Ivanov, Telsa M. Mittelmeier, Timothy A. Bolger, J. Ross Buchan
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1367 (2020)
Stress granules (SGs) are hypothesized to facilitate TAR DNA-binding protein 43 (TDP-43) cytoplasmic mislocalization and aggregation, which may underly amyotrophic lateral sclerosis pathology. However, much data for this hypothesis is indirect. Addit
Externí odkaz:
https://doaj.org/article/319621e9c0384d4b93f98311a09bc493
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 783 (2020)
Ribosomes are perhaps the most critical macromolecular machine as they are tasked with carrying out protein synthesis in cells. They are incredibly complex structures composed of protein components and heavily chemically modified RNAs. The task of as
Externí odkaz:
https://doaj.org/article/99be4b09874444ba976f277633f1066c
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
The original version of this Article contained an error in the spelling of the author Steven M. Coyne, which was incorrectly given as Stephen M. Coyne. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3352bafb4a3145c8b3e2d24ebc7c2cb4
Publikováno v:
FEBS Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff5167187e21d1f08ef10c8f12b2b78
https://doi.org/10.1002/1873-3468.14639
https://doi.org/10.1002/1873-3468.14639