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pro vyhledávání: '"Shawn M. Egan"'
Autor:
Shawn M. Egan, Scott H. Olejniczak, Qing Xiang, Megan R. Radler, Gaspare La Rocca, Craig B. Thompson, Ralph Garippa
Publikováno v:
Molecular and Cellular Biology. 36:2360-2373
Cell growth and proliferation require the coordinated activation of many cellular processes, including cap-dependent mRNA translation. MicroRNAs oppose cap-dependent translation and set thresholds for expression of target proteins. Emerging data sugg
Autor:
G. Aaron Holling, Rachel L. Kandefer, Scott H. Olejniczak, Michael J. Nemeth, Seerat Elahi, Shawn M. Egan
Publikováno v:
Experimental Hematology. 64:45-58.e9
Recent biochemical characterization of Arsenic resistance protein 2 (Ars2) has established it as central to determining the fate of nascent RNA polymerase II (RNAPII) transcripts. Through interactions with the nuclear 5′-7-methylguanosine (7mG) cap
Publikováno v:
Oncotarget
// Shawn M. Egan 1 , Ellen Karasik 2 , Leigh Ellis 3 and Sandra O. Gollnick 4 1 Department of Immunology, Roswell Park Cancer Institute, Buffalo, New York 14263, USA 2 Department of Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffal
Autor:
Shawn M Egan, Sandra O Gollnick
Publikováno v:
The Journal of Immunology. 196:213.17-213.17
Prostate cancer (CaP) is a critical problem for the aging male population. CaP is managed using a combination of prostatectomy, androgen ablation, chemotherapy and radiation. Subsets of patients develop androgen-insensitive metastatic CaP for which t