Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shawn K. Pack"'
Autor:
Shawn K. Pack, David K. Leahy
Publikováno v:
Organic Process Research & Development. 17:1440-1444
A practical and scalable synthesis of phosphonooxymethyl prodrugs of HIV-1 attachment inhibitors is described. Starting from azaindoles 1 and 2, this two-step sequence features an efficient alkylation using chloromethyl phosphate 5 and an exceptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24435210c4dde2dd190e390e353cbbd5
https://doi.org/10.1021/op400225q
https://doi.org/10.1021/op400225q
Publikováno v:
Chemical Engineering Science. 66:88-102
A mechanistic approach to identify the driving force for crystallization and to determine the solubility of solids crystallized from solutions containing multiple conformers is presented. It is assumed that only one conformer, which is referred to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::964285d44c29fa344ff730db1138b8bd
https://doi.org/10.1016/j.ces.2010.10.023
https://doi.org/10.1016/j.ces.2010.10.023
Autor:
Gary A. Molander, Shawn K. Pack
Publikováno v:
Tetrahedron. 59:10581-10591
The scope of the lanthanide mediated, sequential hydroamination/C–C cyclization reaction was determined for the formation of tricyclic and tetracyclic aromatic nitrogen heterocycles. An array of ring sizes was explored to determine the diastereosel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf8b06455cf831195ad48913a3bd010c
https://doi.org/10.1016/j.tet.2003.08.071
https://doi.org/10.1016/j.tet.2003.08.071
Autor:
Bang-Chi Chen, Andrew Rusowicz, Ronald F Eiring, Francis J. Okuniewicz, Valerie Zannella, Kenneth J. Natalie, Shawn K. Pack, Ramesh N. Patel, Steven R. Schwarz, Kai S Tse, John J. Venit, Susan C Durand, John M. Wasylyk, Bruce T Lotz, Keith Ramig, Ronald L. Hanson, John C. Harris, William L. Parker, Shankar Swaminathan, Victor W. Rosso, David A. Lust, Mary Jo Donovan, Laszlo J. Szarka, Mark Liu, Laporte Thomas L, Michael A. Montana, Dana L Cazzulino, Venkata B. Nanduri, Peter J. Bernot, Jeffrey M. Howell
Publikováno v:
Enzyme and Microbial Technology. 26:348-358
Allysine ethylene acetal [(S)-2-amino-5-(1,3-dioxolan-2-yl)-pentanoic acid (2)] was prepared from the corresponding keto acid by reductive amination using phenylalanine dehydrogenase (PDH) from Thermoactinomyces intermedius ATCC 33205. Glutamate, ala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3a09021bd4305ecd5ef317f78de9a3
https://doi.org/10.1016/s0141-0229(99)00175-1
https://doi.org/10.1016/s0141-0229(99)00175-1
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8503ce5192760d43d295dd1aa8eadf1b
https://doi.org/10.1002/chin.199634084
https://doi.org/10.1002/chin.199634084
Publikováno v:
ChemInform. 32
A diastereoselective, lanthanocene-catalyzed, intramolecular hydroamination reaction was applied to the preparation of 2,6-disubstituted piperidines. Various metal/ligand arrays in the catalysts were examined using a model substrate to allow optimiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b23ee87556b0fcfe2bf5c7a3aab5f5
https://doi.org/10.1002/chin.200140216
https://doi.org/10.1002/chin.200140216
Publikováno v:
The Journal of Organic Chemistry. 61:2908-2910
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1db5f3bc1883995128c34e28b2657d
https://doi.org/10.1021/jo952098j
https://doi.org/10.1021/jo952098j
Autor:
Shawn K. Pack, Gary A. Molander
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a1bcd2b0eb44e5214b49ec067c8ead7
https://doi.org/10.1002/chin.200415137
https://doi.org/10.1002/chin.200415137