Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shawn Jeffries"'
Autor:
Karen Rex, Shawn Jeffries, Matthew L Brown, Timothy Carlson, Angela Coxon, Flordeliza Fajardo, Brendon Frank, Darin Gustin, Alexander Kamb, Paul D Kassner, Shyun Li, Yihong Li, Kurt Morgenstern, Matthew Plant, Kim Quon, Astrid Ruefli-Brasse, Joanna Schmidt, Elissa Swearingen, Nigel Walker, Zhulun Wang, J E Vivienne Watson, Dineli Wickramasinghe, Mariwil Wong, Guifen Xu, Holger Wesche
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68328 (2013)
Sphingosine kinases (SPHKs) are enzymes that phosphorylate the lipid sphingosine, leading to the formation of sphingosine-1-phosphate (S1P). In addition to the well established role of extracellular S1P as a mitogen and potent chemoattractant, SPHK a
Externí odkaz:
https://doaj.org/article/dfda1f39979a456d9edd17f32579cba1
Autor:
Shweta Singh, Laura Serwer, Amy DuPage, Kristi Elkins, Niharika Chauhan, Matthew Ravn, Fritz Buchanan, Leyu Wang, Michael Krimm, Ken Wong, Jason Sagert, Kimberly Tipton, Stephen J. Moore, Yuanhui Huang, Andrew Jang, Eric Ureno, Adam Miller, Sarah Patrick, Shanti Duvur, Shouchun Liu, Olga Vasiljeva, Yingchun Li, Tracy Henriques, Ilaria Badagnani, Shawn Jeffries, Siew Schleyer, Rob Leanna, Claus Krebber, Sridhar Viswanathan, Luc Desnoyers, Jonathan Terrett, Marcia Belvin, Susan Morgan-Lappe, W. Michael Kavanaugh, Jennifer Richardson
Publikováno v:
Molecular Cancer Therapeutics. 21:1326-1336
Probody therapeutics (Pb-Txs) are conditionally activated antibody–drug conjugates (ADCs) designed to remain inactive until proteolytically activated in the tumor microenvironment, enabling safer targeting of antigens expressed in both tumor and no
Autor:
Jennifer Richardson, W. Michael Kavanaugh, Susan Morgan-Lappe, Marcia Belvin, Jonathan Terrett, Luc Desnoyers, Sridhar Viswanathan, Claus Krebber, Rob Leanna, Siew Schleyer, Shawn Jeffries, Ilaria Badagnani, Tracy Henriques, Yingchun Li, Olga Vasiljeva, Shouchun Liu, Shanti Duvur, Sarah Patrick, Adam Miller, Eric Ureno, Andrew Jang, Yuanhui Huang, Stephen J. Moore, Kimberly Tipton, Jason Sagert, Ken Wong, Michael Krimm, Leyu Wang, Fritz Buchanan, Matthew Ravn, Niharika Chauhan, Kristi Elkins, Amy DuPage, Laura Serwer, Shweta Singh
Supplementary Data from Nonclinical Efficacy and Safety of CX-2029, an Anti-CD71 Probody–Drug Conjugate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c4baf0734abf8c7e252b8e10c6fd0
https://doi.org/10.1158/1535-7163.22523304.v1
https://doi.org/10.1158/1535-7163.22523304.v1
Autor:
Anthony J. Capobianco, David J. Robbins, Wensi Tao, Shawn Jeffries, Bin Li, Zhiqiang Wang, Xiaoqing Han, Wen Zhou, Ke Jin
Identification of Maml1 acetylation sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061ca1713e08bd639f612b3f6f880f5e
https://doi.org/10.1158/0008-5472.22414884.v1
https://doi.org/10.1158/0008-5472.22414884.v1
Autor:
Anthony J. Capobianco, David J. Robbins, Wensi Tao, Shawn Jeffries, Bin Li, Zhiqiang Wang, Xiaoqing Han, Wen Zhou, Ke Jin
Although it has long been appreciated that p300 acts as a critical Notch coactivator, the mechanistic details of p300 in Notch-mediated transcription remain unclear. We previously demonstrated that PEAK1-related kinase activating pseudokinase 1 (NACK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc46c94db4f415d8bc1734990cfa47f8
https://doi.org/10.1158/0008-5472.c.6509103.v1
https://doi.org/10.1158/0008-5472.c.6509103.v1
Autor:
Anthony J. Capobianco, David J. Robbins, Wensi Tao, Shawn Jeffries, Bin Li, Zhiqiang Wang, Xiaoqing Han, Wen Zhou, Ke Jin
supplemental figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1592ae4d8d2a8797db52be4c718787
https://doi.org/10.1158/0008-5472.22414878.v1
https://doi.org/10.1158/0008-5472.22414878.v1
Autor:
Leah P. Cheatham, Misty Creel, Avani Shah, Will Hasenbein, Nyshetia White-Chapman, Shawn Jeffries, Debra Nelson-Gardell
Publikováno v:
Families in Society: The Journal of Contemporary Social Services. 100:52-67
Child welfare workers (CWWs) face challenges to engaging families, including initial parental resistance, service plan noncompliance and other barriers. Adopting a motivational interviewing (MI) framework may improve engagement and collaboration betw
Autor:
Christopher Conn, D. Ross Camidge, Yusuke Okuma, Tatiana Hernandez Guerrero, Satwant Lally, Melissa Lynne Johnson, Alona Zer, Xiaohua Xin, Julio Antonio Peguero, Lan Wang, Maria de Miguel, Edwin E. Jeng, Jair Bar, Shawn Jeffries, Daniel Morgensztern, Eric Scott Schaefer, Mor Moskovitz, Kiyotaka Yoh
Publikováno v:
Journal of Clinical Oncology. 39:TPS3142-TPS3142
TPS3142 Background: Protein tyrosine kinase 7 (PTK7) is a highly conserved receptor tyrosine kinase involved in the Wnt signaling pathway and is overexpressed in multiple cancer types, including non-small cell lung cancer (NSCLC). Cofetuzumab pelidot
Autor:
Shawn Jeffries, Ke Jin, Xiaoqing Han, David J. Robbins, Wensi Tao, Bin Li, Wen Zhou, Zhiqiang Wang, Anthony J. Capobianco
Publikováno v:
Cancer research. 77(16)
Although it has long been appreciated that p300 acts as a critical Notch coactivator, the mechanistic details of p300 in Notch-mediated transcription remain unclear. We previously demonstrated that PEAK1-related kinase activating pseudokinase 1 (NACK
Publikováno v:
Molecular and Cellular Biology. 22:3927-3941
Notch genes encode a family of transmembrane proteins that are involved in many cellular processes, such as differentiation, proliferation, and apoptosis. It is well established that all four Notch genes can act as oncogenes; however, the mechanism b