Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shawn Hill"'
Autor:
Elizabeth M. Anderson, Francesco R. Simonetti, Robert J. Gorelick, Shawn Hill, Monica A. Gouzoulis, Jennifer Bell, Catherine Rehm, Liliana Pérez, Eli Boritz, Xiaolin Wu, Daria Wells, Stephen H. Hughes, Venigalla Rao, John M. Coffin, Mary F. Kearney, Frank Maldarelli
Publikováno v:
Viruses, Vol 12, Iss 2, p 136 (2020)
Combination antiretroviral therapy (cART) controls but does not eradicate HIV infection; HIV persistence is the principal obstacle to curing infections. The proportion of defective proviruses increases during cART, but the dynamics of this process ar
Externí odkaz:
https://doaj.org/article/98e69d565b514117a7bf0360817fab15
Autor:
Kristi Huik, Shawn Hill, Jomy George, Alice Pau, Safia Kuriakose, Camille M. Lange, Nicola Dee, Pamela Stoll, Muhammad Khan, Tauseef Rehman, Catherine A. Rehm, Robin Dewar, Zehava Grossman, Frank Maldarelli
Publikováno v:
AIDS (London, England). 36(13)
The integrase strand transfer inhibitor (INSTI) dolutegravir is commonly used in combination antiretroviral therapy regimens and retains strong potency even with primary resistance mutations to some other INSTIs. Acquisition of accessory mutations to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e481bd461076c86f3b0c39538ac34987
https://pubmed.ncbi.nlm.nih.gov/35848510
https://pubmed.ncbi.nlm.nih.gov/35848510
Publikováno v:
Policing: An International Journal. 44:786-799
PurposeThe purpose of this paper is to describe a theory-driven intervention called VOICES that was developed to improve police-community relations. The intervention was designed based on principles derived from social psychological theories of inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f61cb40295249b7e371b28fa4d720a11
https://doi.org/10.1108/pijpsm-09-2020-0154
https://doi.org/10.1108/pijpsm-09-2020-0154
Autor:
Stephen H. Hughes, Shawn Hill, Elizabeth M. Anderson, Francesco R. Simonetti, Eli Boritz, Mary F. Kearney, Frank Maldarelli, Daria Wells, Xiaolin Wu, Venigalla B. Rao, Catherine Rehm, Jennifer Bell, John M. Coffin, Robert J. Gorelick, Liliana Pérez, Monica A Gouzoulis
Publikováno v:
Viruses
Viruses, Vol 12, Iss 2, p 136 (2020)
Volume 12
Issue 2
Viruses, Vol 12, Iss 2, p 136 (2020)
Volume 12
Issue 2
Combination antiretroviral therapy (cART) controls but does not eradicate HIV infection
HIV persistence is the principal obstacle to curing infections. The proportion of defective proviruses increases during cART, but the dynamics of this proces
HIV persistence is the principal obstacle to curing infections. The proportion of defective proviruses increases during cART, but the dynamics of this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaeb622f59848253dc78b295e861ec1
https://pubmed.ncbi.nlm.nih.gov/31991737
https://pubmed.ncbi.nlm.nih.gov/31991737
Autor:
M. Gouzoulis, R. Yarchoan, Jennifer Bell, Frank Maldarelli, Stephen M. Hewitt, Sheila Kumar, Shawn Hill, P. Rote, D. E. Kleiner, Mary F. Kearney, Giorgio Bozzi, Robert J. Gorelick, Catherine Rehm, Francesco R. Simonetti, Junko Hattori, Thomas S. Uldrick, Wei Shao, Stephen A. Wank, Sarah A. Watters, C. Lange, Michael J. Bale, B. Fullmer, Elizabeth M. Anderson, Z. Grossman
Publikováno v:
Science Advances
Long-term persistence, not ongoing virus replication, is primarily responsible for maintaining HIV during antiretroviral therapy.
HIV persistence during combination antiretroviral therapy (cART) is the principal obstacle to cure. Mechanisms resp
HIV persistence during combination antiretroviral therapy (cART) is the principal obstacle to cure. Mechanisms resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ab96a62210d835be0d733b4e738581
http://europepmc.org/articles/PMC6760922
http://europepmc.org/articles/PMC6760922
Autor:
Shawn Hill, David Wells, Michael J. Bale, Mary F. Kearney, John W. Mellors, John M. Coffin, Stephen H. Hughes, Joseph J. Eron, Shuang Guo, Joann D. Kuruc, Francesco R. Simonetti, Brian T. Luke, Frank Maldarelli, Xiaolin Wu, Jonathan Spindler, Jennifer M. Zerbato
Publikováno v:
JCI insight. 4(12)
In HIV-infected individuals on long-term antiretroviral therapy (ART), more than 40% of the infected cells are in clones. Although most HIV proviruses present in individuals on long-term ART are defective, including those in clonally expanded cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478b5d35e92e579409912ccd952b1904
https://pubmed.ncbi.nlm.nih.gov/31217357
https://pubmed.ncbi.nlm.nih.gov/31217357
Autor:
Elias K. Halvas, Jonathan Spindler, John W. Mellors, Catherine Rehm, Michael Piatak, Sarah A. Watters, Michael A. Polis, Mary F. Kearney, Francesco R. Simonetti, Stephen H. Hughes, Thomas S. Uldrick, Elizabeth Fyne, Joseph A. Kovacs, Frank Maldarelli, Junko Hattori, John M. Coffin, Kerri J. Penrose, Brandon F. Keele, Guillaume Besson, Wei Shao, Robert J. Gorelick, Li Su, David Wells, Michele D. Sobolewski, Shawn Hill, Richard Kwan, Deborah Citrin, Zhiming Yang, Brian T. Luke, Elizabeth M. Anderson, Xiaolin Wu, Carter Van Waes
Publikováno v:
Proceedings of the National Academy of Sciences. 113:1883-1888
Significance Reservoirs of HIV-infected cells persist during antiretroviral therapy, and understanding persistence is essential to develop HIV curative strategies. During replication, HIV integrates into the host genome; most proviruses are not infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c2e8dcd73d7f79d82181ad0d05078b6
https://doi.org/10.1073/pnas.1522675113
https://doi.org/10.1073/pnas.1522675113
Autor:
Kathryn Hinchee-Rodriguez, Kamil Hercík, Judith G. Levin, Chang-Hyeock Byeon, Lisa M. Charlton, Gabriel Nam, Angela M. Gronenborn, Mithun Mitra, Gisela Heidecker, In-Ja L. Byeon, Jinwoo Ahn, Dustin Singer, Shawn Hill
Publikováno v:
Nucleic Acids Research
Human APOBEC3A (A3A) is a single-domain cytidine deaminase that converts deoxycytidine residues to deoxyuridine in single-stranded DNA (ssDNA). It inhibits a wide range of viruses and endogenous retroelements such as LINE-1, but it can also edit geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf9a9eb1a57d0f0a8d0454248d69c8d
https://doi.org/10.1093/nar/gkt945
https://doi.org/10.1093/nar/gkt945
Autor:
Sara Jones, Kei Sato, Frank Maldarelli, Eleanor Wilson, Wei-Shau Hu, Shawn Hill, Hibiki Doi, Taisuke Izumi, W. Gregory Alvord, Yoshio Koyanagi, Wei Shao, Ryan C. Burdick, Vinay K. Pathak, Belete Ayele Desimmie
Publikováno v:
Nucleic Acids Research
Although APOBEC3 cytidine deaminases A3G, A3F, A3D and A3H are packaged into virions and inhibit viral replication by inducing G-to-A hypermutation, it is not known whether they are copackaged and whether they can act additively or synergistically to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c2c7235dcb2783db64fa49e8b06692
https://pubmed.ncbi.nlm.nih.gov/27439715
https://pubmed.ncbi.nlm.nih.gov/27439715
Autor:
Sara Jones, Francesco R. Simonetti, Shawn Hill, Catherine Rehm, Rob Gorelick, Jennifer Bell, Elizabeth M. Anderson, Mary F. Kearney
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 77:56-56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dfbf0dfff6d8cc12f8b9892a1e3de90
https://doi.org/10.1097/01.qai.0000532505.40030.f8
https://doi.org/10.1097/01.qai.0000532505.40030.f8