Zobrazeno 1 - 10
of 332
pro vyhledávání: '"Shawn G Kwatra"'
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 5, Pp n/a-n/a (2022)
Abstract Atopic dermatitis is a chronic inflammatory skin disease. Patients with atopic dermatitis experience inflammatory lesions associated with intense itch and pain, which lead to sleep disturbance and poor mental health and quality of life. We r
Externí odkaz:
https://doaj.org/article/247dbf3b87e346a88c1270664242f8de
Autor:
Kun-Hsing Yu, Shannon Wongvibulsin, William Murphy, Leyre Zubiri, Vartan Pahalyants, Mark Kalinich, Feicheng Wang, Vivek Naranbhai, Alexander Gusev, Chenyue Lu, Shawn G Kwatra, Yevgeniy R Semenov
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Immune-related adverse events (irAEs) are a serious side effect of immune checkpoint inhibitor (ICI) therapy for patients with advanced cancer. Currently, predisposing risk factors are undefined but understanding which patients are at incr
Externí odkaz:
https://doaj.org/article/a4140872710d449cbfe5498337fb0343
Autor:
James Meixiong, Chirag Vasavda, Dustin Green, Qin Zheng, Lijun Qi, Shawn G Kwatra, James P Hamilton, Solomon H Snyder, Xinzhong Dong
Publikováno v:
eLife, Vol 8 (2019)
Various pathologic conditions result in jaundice, a yellowing of the skin due to a buildup of bilirubin. Patients with jaundice commonly report experiencing an intense non-histaminergic itch. Despite this association, the pruritogenic capacity of bil
Externí odkaz:
https://doaj.org/article/196c58b6bcf145c68e4163a53c5f82d0
Autor:
Andrew F. Alexis, Melinda Gooderham, Shawn G. Kwatra, Ahmad Amin, Susan Taylor, Ramon Espaillat, Trisha Rettig, Tianshuang Wu, Linyu Shi, Mark I. Kaldas, Deanne M. Dilley, Ranjeeta Sinvhal, Chudy Nduaka, Benjamin Lockshin
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 10, Pp 2877-2887 (2024)
Abstract Introduction Historically, patients with skin of color are underdiagnosed with psoriasis and underrepresented in clinical trials. In this study, we assess the efficacy and safety of risankizumab in patients with moderate-to-severe plaque pso
Externí odkaz:
https://doaj.org/article/df8dd512e8ae4dd9b06c7159a85f4dee
Autor:
Gil Yosipovitch, MD, Brian S. Kim, MD, Shawn G. Kwatra, MD, Nicholas K. Mollanazar, MD, Sonja Ständer, MD, Takahiro Satoh, MD, PhD, Pedro Mendes-Bastos, MD, Tsen-Fang Tsai, MD, Elizabeth Laws, PhD, Michael C. Nivens, PhD, Jennifer Maloney, MD, Genming Shi, PhD, Ashish Bansal, MD, MBA, Ariane Dubost-Brama, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 163-174 (2024)
Background: Phase 3 PRIME/PRIME2 trials independently demonstrated efficacy and an acceptable safety profile of dupilumab adults with moderate-to-severe prurigo nodularis. Objective: To obtain a more precise estimate of onset and magnitude of treatme
Externí odkaz:
https://doaj.org/article/711afba8cadd4d1c95210d2031b7c4d3
Autor:
Jaya Manjunath, BS, Viviane Liao, BS, Anusha Kambala, BS, Aaron Bao, BA, Alexander L. Kollhoff, MD, Emily Z. Ma, BS, Brenda Umenita Imo, MS, Hannah Cornman, BS, Sriya V. Reddy, BS, Kevin K. Lee, BS, Weiying Lu, BS, Selina M. Yossef, BA, Madan M. Kwatra, PhD, Shawn G. Kwatra, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 97-102 (2024)
Background: Chronic pruritus (CP) is a poorly characterized condition associated with intense pruritus without a primary skin eruption. This condition tends to emerge more commonly in older adults, and there is limited research on triggering factors.
Externí odkaz:
https://doaj.org/article/4057541bba474abb8f97bd8604389b6b
More Time Spent with Clear Skin and No Itch with Upadacitinib versus Dupilumab for Atopic Dermatitis
Autor:
Andrew Blauvelt, Kilian Eyerich, Alan D. Irvine, Marjolein de Bruin-Weller, Shawn G. Kwatra, Melinda Gooderham, Brian Kim, Brian M. Calimlim, Wan-Ju Lee, Eliza M. Raymundo, Yingyi Liu, Sarah Ofori, Andrew M. Platt, Jonathan I. Silverberg
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 9, Pp 2621-2630 (2024)
Abstract Introduction Atopic dermatitis (AD), with its hallmark symptoms of pruritus and skin lesions, often impairs patients’ quality of life. We assessed time spent with clear/almost clear skin and no/minimal itch during upadacitinib treatment ve
Externí odkaz:
https://doaj.org/article/f20cd55b09a34e87a0a91cfbd7f735cf
Autor:
Jaya Manjunath, Varsha Parthasarathy, Marina Z. Joel, Junwen Deng, Emily Z. Ma, Kevin K. Lee, Thomas Pritchard, Shenghao Guo, Cissy Zhang, Madan M. Kwatra, Anne Le, Shawn G. Kwatra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic pruritus of unknown origin (CPUO) is characterized by chronic itch for 6 weeks or greater without an identifiable primary cause. Studies are needed to investigate circulating blood biomarkers to elucidate disease pathogenesis. The ob
Externí odkaz:
https://doaj.org/article/1acfa06fe5514aafb864c485e9168250
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 6, Pp 1371-1387 (2024)
Abstract Chronic spontaneous urticaria (CSU) is an unpredictable inflammatory skin condition characterized by the spontaneous onset of itchy wheals, angioedema, or both, which occurs for longer than 6 weeks overall. Despite the relatively straightfor
Externí odkaz:
https://doaj.org/article/b410a0b9609d4f62aa89a1de2dffb5c9
Autor:
Shawn G. Kwatra, Saakshi Khattri, Ahmad Z. Amin, Roberto Ranza, Blair Kaplan, Linyu Shi, Byron Padilla, Ahmed M. Soliman, Dennis McGonagle
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 6, Pp 1517-1530 (2024)
Abstract Introduction The presence (vs absence) of enthesitis/dactylitis is associated with greater psoriatic arthritis (PsA) activity and reduced health-related quality of life. Risankizumab, an interleukin 23 antagonist, demonstrated superior treat
Externí odkaz:
https://doaj.org/article/208376fab02442ef8617f079f73a4f2b